NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
78 kgBSA = 1.68 m²175 mg/m²D = ? mg

A patient weighing 78 kg has a body surface area of 1.68 m². The prescription is 175 mg/m². Find the dose D in mg.

78 kgBSA = 1.68 m²175 mg/m²
D = mg
2.Dosage calculationsHard
00.10.20.30.40.50.60.70.80.911 mL

The prescription is 1200 micrograms. The ampoule contains 2 mg/mL. Draw up the dose in the 1 mL syringe: what volume V do you give?

1200 mcg2 mg/mL
V = mL
3.IV infusion ratesMedium
20 gtt/mL90 mL/h? gtt/min

An infusion is ordered at 90 mL/h, but no pump is available. It runs by gravity through a giving set of 20 gtt/mL. Find the drip rate R in drops per minute.

90 mL/h20 gtt/mL
R = gtt/min
4.IV infusion ratesHard
400 mg500 mL8 mL/h? mg/h

A bag contains 400 mg of a drug in 500 mL and runs at 8 mL/h. How many milligrams per hour D does the patient receive?

400 mg/500 mL8 mL/h
D = mg/h
5.Pediatric & critical-care dosingMedium
50 units250 mLregular insulin3 mL/h? units/h

Practice exercise (made-up values, not clinical guidance). An infusion of 50 units of regular insulin in 250 mL runs at 3 mL/h. How many units per hour D does the patient receive?

50 units/250 mL3 mL/h
D = units/h
6.Pediatric & critical-care dosingHard
400 mg250 mLdopamine24 mL/h55 kg? mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A dopamine infusion of 400 mg in 250 mL runs at 24 mL/h. The patient weighs 55 kg. What dose D in mcg/kg/min is the patient receiving? Round to one decimal place.

400 mg/250 mL24 mL/h55 kg
D = mcg/kg/min
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftsoup250 mLmilk100 mLice chips200 mLIV infusion75 mL/h × 8 hIV antibiotic2 × 100 mLurine200 mLurine250 mLurine250 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the fluid balance B = intake − output in mL (a negative answer means a net loss). Count ice chips as half their volume.

soup: 250 mLmilk: 100 mLice chips: 200 mLIV infusion: 75 mL/h × 8 hIV antibiotic: 2 × 100 mLurine: 200 mLurine: 250 mLurine: 250 mL
B = mL
8.IV fluids & fluid balanceHard
1000 mL60 mL/hstart 10:0014:30: ? mL

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag was started at 10:00 and runs by pump at 60 mL/h. How many mL V are left in the bag at 14:30?

1000 mL60 mL/h10:00 → 14:30
V = mL
9.Nursing math & unit conversionsMedium
1234567891011128:20 PM?08:2021:2019:2020:20

Practice exercise (made-up values, not clinical guidance). A dose is charted at 8:20 PM. Which entry is the same time on the 24-hour clock? Click it.

8:20 PM
  1. 108:20
  2. 221:20
  3. 319:20
  4. 420:20
10.Nursing math & unit conversionsHard
2 tbsp? mL2 fl oz? mL½ cup? mLΣ = ? mL

Practice exercise (made-up values, not clinical guidance). During a shift a patient takes 2 tbsp of liquid supplement, 2 fl oz of juice, ½ cup of tea. Using the equivalents given, find the total oral intake V in mL.

1 tbsp = 15 mL1 fl oz = 30 mL1 cup = 8 fl oz = 240 mL
V = mL

3Solutions

1.Dosage calculations

Answer: D = 294 mg

Body-surface-area dosing: many cytotoxic and some paediatric doses are prescribed per square metre of body surface area: dose (mg) = dose per m² × BSA (m²). The Mosteller formula estimates BSA = √(height (cm) × weight (kg)/3600).

Dose

D = 175·1.68 = 294 mg

Answer

D = 294 mg
2.Dosage calculations

Answer: V = 0.6 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Same units

2 mg/mL = 2000 mcg/mL

Volume

V = 1200/2000 = 0.6 mL

Answer

V = 0.6 mL
3.IV infusion rates

Answer: R = 30 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Millilitres per minute

90/60 = 1.5 mL/min

Drip rate

R = 1.5·20 = 30 gtt/min

Answer

R = 30 gtt/min
4.IV infusion rates

Answer: D = 6.4 mg/h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Concentration

400/500 = 0.8 mg/mL

Dose rate

D = 0.8·8 = 6.4 mg/h

Answer

D = 6.4 mg/h
5.Pediatric & critical-care dosing

Answer: D = 0.6 units/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

50/250 = 0.2 units/mL

Units per hour

D = 3·0.2 = 0.6 units/h

Answer

D = 0.6 units/h
6.Pediatric & critical-care dosing

Answer: D = 11.6 mcg/kg/min

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

400 000/250 = 1600 mcg/mL

Micrograms per minute

24·1600 = 38400 mcg/h
38400/60 = 640 mcg/min

Per kilogram

D = 640/55 = 11.64 ≈ 11.6 mcg/kg/min

Answer

D = 11.6 mcg/kg/min
7.IV fluids & fluid balance

Answer: B = 550 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total intake

oral: 250 + 100 = 350 mL
ice chips: 200/2 = 100 mL
IV infusion: 75·8 = 600 mL
IV antibiotic: 2·100 = 200 mL
total intake = 1250 mL

Total output

200 + 250 + 250 = 700 mL

Balance

B = 1250 − 700 = 550 mL

Answer

B = 550 mL

Positive: more fluid went in than came out.

8.IV fluids & fluid balance

Answer: V = 730 mL

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Elapsed time

10:00 → 14:30 = 4.5 h

Volume infused

60·4.5 = 270 mL

Volume left

V = 1000 − 270 = 730 mL

Answer

V = 730 mL
9.Nursing math & unit conversions

Answer: 20:20

24-hour clock: from 1 PM onwards add 12 to the hour (3:45 PM = 15:45). Midnight to 12:59 AM is 00:00–00:59, and 12:00–12:59 PM stays 12:00–12:59. Going back, subtract 12 from hours 13–23 and add PM; hours 00 become 12 AM. Count time across midnight in two parts: up to 24:00 (00:00), then from 00:00 on.

Convert the hour

8 PM → 8 + 12 = 20

Answer

20:20

Answer

20:20
10.Nursing math & unit conversions

Answer: V = 210 mL

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Each item in mL

2 tbsp = 2·15 = 30 mL
2 fl oz = 2·30 = 60 mL
½ cup = 0.5·240 = 120 mL

Add

V = 30 + 60 + 120 = 210 mL

Answer

V = 210 mL

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