NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
22 kg25 mg/kg/day2× per dayD = ? mg

A patient weighs 22 kg. The prescribed dose is 25 mg/kg per day, given in 2 equal doses. How many milligrams D are given per dose?

22 kg25 mg/kg/day2× per day
D = mg
2.Dosage calculationsHard
00.10.20.30.40.50.60.70.80.911 mL

The prescription is 610 units of a drug that comes as 1000 units/mL. Draw up the dose in the 1 mL syringe: what volume V do you give?

610 units1000 units/mL
V = mL
3.IV infusion ratesMedium
250 mL15 gtt/mL2 h? gtt/min

Infuse 250 mL over 2 hours with a giving set of 15 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.

250 mL2 h15 gtt/mL
R = gtt/min
4.IV infusion ratesHard
300 mL60 gtt/mL42 gtt/mint = ? h

A drip runs at 42 gtt/min through a set of 60 gtt/mL. There are 300 mL left in the bag. How many hours t until it is empty? Round to one decimal place.

42 gtt/min60 gtt/mL300 mL
t = h
5.Pediatric & critical-care dosingMedium
100 units100 mLregular insulin? mL/h99 kg0.1 units/kg/h

Practice exercise (made-up values, not clinical guidance). An infusion contains 100 units of regular insulin in 100 mL. The order is 0.1 units/kg/h for a patient who weighs 99 kg. Find the pump rate R in mL/h. Round to one decimal place.

100 units/100 mL0.1 units/kg/h99 kg
R = mL/h
6.Pediatric & critical-care dosingHard
800 mg500 mLdopamine18 mL/h77 kg? mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A dopamine infusion of 800 mg in 500 mL runs at 18 mL/h. The patient weighs 77 kg. What dose D in mcg/kg/min is the patient receiving? Round to one decimal place.

800 mg/500 mL18 mL/h77 kg
D = mcg/kg/min
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftwater200 mLmilk240 mLIV infusion75 mL/h × 8 hIV antibiotic2 × 50 mLurine200 mLurine175 mLurine150 mLurine300 mLwound drain120 mLvomit250 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The patient weighs 100 kg. Find the average urine output U in mL/kg/h. Round to two decimal places.

100 kg8 hurine: 200 mLurine: 175 mLurine: 150 mLurine: 300 mLwound drain: 120 mLvomit: 250 mL
U = mL/kg/h
8.IV fluids & fluid balanceHard
500 mL→ 150 mL/hstart 11:00ttotal​ = ? h75 mL/h × 2 h

Practice exercise (made-up values, not clinical guidance). A 500 mL infusion starts at 11:00 at 75 mL/h. After 2 hours the rate is changed to 150 mL/h and is not changed again. How many hours t after the start will the bag be empty? Round to one decimal place.

500 mL75 mL/h · 2 h150 mL/h
t = h
9.Nursing math & unit conversionsMedium
94969810010210410635363738394041°F°C105.5 °F? °C

Practice exercise (made-up values, not clinical guidance). A patient’s temperature is 105.5 °F. Convert it to degrees Celsius T with °C = (°F − 32) × 5/9. Round to one decimal place.

105.5 °F
T = °C
10.Nursing math & unit conversionsHard
00:0020:5008:55t = ?

Practice exercise (made-up values, not clinical guidance). An infusion starts at 20:50 and finishes at 08:55 the next morning (24-hour clock). How many minutes t did it run?

20:5008:55
t = min

3Solutions

1.Dosage calculations

Answer: D = 275 mg

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Total per day

25·22 = 550 mg

Per dose

D = 550/2 = 275 mg

Answer

D = 275 mg
2.Dosage calculations

Answer: V = 0.61 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Volume

V = 610/1000 = 0.61 mL

On the syringe

On this 1 mL syringe every small line is 0.01 mL.

Answer

V = 0.61 mL
3.IV infusion rates

Answer: R = 31 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

2·60 = 120 min

Drip rate

R = 250·15/120 = 31.25 ≈ 31 gtt/min

Answer

R = 31 gtt/min

At the bedside you round to the nearest whole drop: 31 gtt/min.

4.IV infusion rates

Answer: t = 7.1 h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

42·60/60 = 42 mL/h

Time left

t = 300/42 = 7.143 ≈ 7.1 h

Answer

t = 7.1 h
5.Pediatric & critical-care dosing

Answer: R = 9.9 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

0.1·99 = 9.9 units/h

Concentration

100/100 = 1 units/mL

Pump rate

R = 9.9/1 = 9.9 mL/h

Answer

R = 9.9 mL/h
6.Pediatric & critical-care dosing

Answer: D = 6.2 mcg/kg/min

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

800 000/500 = 1600 mcg/mL

Micrograms per minute

18·1600 = 28800 mcg/h
28800/60 = 480 mcg/min

Per kilogram

D = 480/77 = 6.234 ≈ 6.2 mcg/kg/min

Answer

D = 6.2 mcg/kg/min
7.IV fluids & fluid balance

Answer: U = 1.03 mL/kg/h

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total urine

200 + 175 + 150 + 300 = 825 mL

Per kilogram per hour

U = 825/(100·8) = 1.031 ≈ 1.03 mL/kg/h

Answer

U = 1.03 mL/kg/h
8.IV fluids & fluid balance

Answer: t = 4.3 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

First part

75·2 = 150 mL
500 − 150 = 350 mL left

Second part

350/150 = 2.333 h

Total time

t = 2 + 2.333 = 4.333 ≈ 4.3 h

Answer

t = 4.3 h

That is about 4 h 20 min, so the bag runs out at about 15:20.

9.Nursing math & unit conversions

Answer: T = 40.8 °C

Temperature: °C = (°F − 32) × 5/9 and °F = °C × 9/5 + 32. Subtract 32 before you multiply when going from °F, and add 32 after you multiply when going from °C. A quick check: 37 °C is 98.6 °F, and every 1 °C is 1.8 °F.

Subtract 32

105.5 − 32 = 73.5

Multiply by 5/9

T = 73.5·5/9 = 40.83 ≈ 40.8 °C

Answer

T = 40.8 °C
10.Nursing math & unit conversions

Answer: t = 725 min

24-hour clock: from 1 PM onwards add 12 to the hour (3:45 PM = 15:45). Midnight to 12:59 AM is 00:00–00:59, and 12:00–12:59 PM stays 12:00–12:59. Going back, subtract 12 from hours 13–23 and add PM; hours 00 become 12 AM. Count time across midnight in two parts: up to 24:00 (00:00), then from 00:00 on.

Before midnight

20:50 → 24:00 = 190 min

After midnight

00:00 → 08:55 = 535 min

Total

t = 190 + 535 = 725 min

Answer

t = 725 min

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