NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
1 g+ 9.6 mLV = ? mL

A vial contains 1 g of powder. The label says: add 9.6 mL of water for injection to give a total volume of 10 mL. The prescription is 100 mg. What volume V of the reconstituted solution do you give?

1 g+ 9.6 mL → 10 mL100 mg
V = mL
2.Dosage calculationsHard
00.10.20.30.40.50.60.70.80.911 mL

The prescription is 3900 units of a drug that comes as 10000 units/mL. Draw up the dose in the 1 mL syringe: what volume V do you give?

3900 units10000 units/mL
V = mL
3.IV infusion ratesMedium
1000 mL15 gtt/mL4 h? gtt/min

Infuse 1000 mL over 4 hours with a giving set of 15 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.

1000 mL4 h15 gtt/mL
R = gtt/min
4.IV infusion ratesHard
730 mLleft? mL/h3 h left

1500 mL was ordered over 8 hours. After 5 hours you find that 730 mL is still in the bag, and the order must still finish on time. By what percentage Δ must the original pump rate be increased?

1500 mL / 8 hafter 5 h: 730 mL
Δ = %
5.Pediatric & critical-care dosingMedium
heparin 5 000 units/mL70 units/kg · 70 kg → V = ? mL

Practice exercise (made-up values, not clinical guidance). A practice protocol calls for a heparin bolus of 70 units/kg for a patient who weighs 70 kg. The vial contains 5 000 units/mL. What volume V do you draw up? Round to two decimal places.

70 units/kg70 kg5 000 units/mL
V = mL
6.Pediatric & critical-care dosingHard
800 mg500 mLdopamine? mL/h78 kg5 mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A bag contains dopamine 800 mg in 500 mL. The order is 5 mcg/kg/min for a patient who weighs 78 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

800 mg/500 mL5 mcg/kg/min78 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput12-hour shiftwater350 mLjuice120 mLice chips100 mLIV infusion50 mL/h × 12 hIV antibiotic2 × 50 mLurine325 mLurine150 mLurine325 mLwound drain100 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the fluid balance B = intake − output in mL (a negative answer means a net loss). Count ice chips as half their volume.

water: 350 mLjuice: 120 mLice chips: 100 mLIV infusion: 50 mL/h × 12 hIV antibiotic: 2 × 50 mLurine: 325 mLurine: 150 mLurine: 325 mLwound drain: 100 mL
B = mL
8.IV fluids & fluid balanceHard
1000 mL100 mL infused120 mL/h13:00t = ? h

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag runs by pump at 120 mL/h. At 13:00, 100 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

1000 mL100 mL infused120 mL/h
t = h
9.Nursing math & unit conversionsMedium
9 lb 10 oz? kg1 lb = 16 oz1 kg = 2.2 lb

Practice exercise (made-up values, not clinical guidance). A newborn weighs 9 lb 10 oz. Using 1 lb = 16 oz and 1 kg = 2.2 lb, find the weight m in kilograms. Round to two decimal places.

9 lb 10 oz1 lb = 16 oz1 kg = 2.2 lb
m = kg
10.Nursing math & unit conversionsHard
4 tbsp? mL¼ cup? mL3 fl oz? mL½ tsp? mLΣ = ? mL

Practice exercise (made-up values, not clinical guidance). During a shift a patient takes 4 tbsp of liquid supplement, ¼ cup of tea, 3 fl oz of juice, ½ tsp of cough syrup. Using the equivalents given, find the total oral intake V in mL.

1 tbsp = 15 mL1 cup = 8 fl oz = 240 mL1 fl oz = 30 mL1 tsp = 5 mL
V = mL

3Solutions

1.Dosage calculations

Answer: V = 1 mL

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Concentration after mixing

1000 mg/10 mL = 100 mg/mL

Volume

V = 100/100 = 1 mL

Answer

V = 1 mL
2.Dosage calculations

Answer: V = 0.39 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Volume

V = 3900/10000 = 0.39 mL

On the syringe

On this 1 mL syringe every small line is 0.01 mL.

Answer

V = 0.39 mL
3.IV infusion rates

Answer: R = 63 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

4·60 = 240 min

Drip rate

R = 1000·15/240 = 62.5 ≈ 63 gtt/min

Answer

R = 63 gtt/min

At the bedside you round to the nearest whole drop: 63 gtt/min.

4.IV infusion rates

Answer: Δ = 29.78 %

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Original rate

1500/8 = 187.5 mL/h

New rate

R = 730/3 = 243.3 mL/h

Percentage change

Δ = (243.3 − 187.5)/187.5·100% = 29.78%

Answer

Δ = 29.78%

This is more than a 25% increase: most hospitals require you to contact the prescriber instead of catching up, and to assess the patient for fluid overload.

5.Pediatric & critical-care dosing

Answer: V = 0.98 mL

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units needed

70·70 = 4 900 units

Volume

V = 4900/5000 = 0.98 mL

Answer

V = 0.98 mL
6.Pediatric & critical-care dosing

Answer: R = 14.6 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

800 mg = 800 000 mcg
800 000/500 = 1600 mcg/mL

Dose per minute and per hour

5·78 = 390 mcg/min
390·60 = 23400 mcg/h

Pump rate

R = 23400/1600 = 14.63 ≈ 14.6 mL/h

Answer

R = 14.6 mL/h
7.IV fluids & fluid balance

Answer: B = 320 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total intake

oral: 350 + 120 = 470 mL
ice chips: 100/2 = 50 mL
IV infusion: 50·12 = 600 mL
IV antibiotic: 2·50 = 100 mL
total intake = 1220 mL

Total output

325 + 150 + 325 + 100 = 900 mL

Balance

B = 1220 − 900 = 320 mL

Answer

B = 320 mL

Positive: more fluid went in than came out.

8.IV fluids & fluid balance

Answer: t = 7.5 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

1000 − 100 = 900 mL

Time

t = 900/120 = 7.5 h

Answer

t = 7.5 h

That is about 7 h 30 min, so the bag runs out at about 20:30.

9.Nursing math & unit conversions

Answer: m = 4.38 kg

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Ounces to pounds

10 oz/16 = 0.625 lb
9 + 0.625 = 9.625 lb

Pounds to kilograms

m = 9.625/2.2 = 4.375 ≈ 4.38 kg

Answer

m = 4.38 kg
10.Nursing math & unit conversions

Answer: V = 212.5 mL

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Each item in mL

4 tbsp = 4·15 = 60 mL
¼ cup = 0.25·240 = 60 mL
3 fl oz = 3·30 = 90 mL
½ tsp = 0.5·5 = 2.5 mL

Add

V = 60 + 60 + 90 + 2.5 = 212.5 mL

Answer

V = 212.5 mL

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