NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
024681010 mL

A child weighing 30 kg is prescribed 5 mg/kg of a drug. The stock solution contains 25 mg/mL. Draw up the dose: what volume V do you give?

30 kg5 mg/kg25 mg/mL
V = mL
2.Dosage calculationsHard
00.10.20.30.40.50.60.70.80.911 mL

The prescription is 0.25 mg. The ampoule contains 500 micrograms per mL. Draw up the dose in the 1 mL syringe: what volume V do you give?

0.25 mg500 mcg/mL
V = mL
3.IV infusion ratesMedium
500 mL20 gtt/mL12 h? gtt/min

Infuse 500 mL over 12 hours with a giving set of 20 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.

500 mL12 h20 gtt/mL
R = gtt/min
4.IV infusion ratesHard
1000 mg250 mL60 gtt/mL240 mg/h? gtt/min

1000 mg of a drug is diluted in 250 mL and given by gravity through a set of 60 gtt/mL. The order is 240 mg per hour. Find the drip rate R in drops per minute.

1000 mg/250 mL240 mg/h60 gtt/mL
R = gtt/min
5.Pediatric & critical-care dosingMedium
25 000 units250 mLheparin? mL/h97 kg15 units/kg/h

Practice exercise (made-up values, not clinical guidance). A bag contains 25 000 units of heparin in 250 mL. The order is 15 units/kg/h for a patient who weighs 97 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

25 000 units/250 mL15 units/kg/h97 kg
R = mL/h
6.Pediatric & critical-care dosingHard
800 mg500 mLdopamine23 mL/h68 kg? mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A dopamine infusion of 800 mg in 500 mL runs at 23 mL/h. The patient weighs 68 kg. What dose D in mcg/kg/min is the patient receiving? Round to one decimal place.

800 mg/500 mL23 mL/h68 kg
D = mcg/kg/min
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftjelly120 mLmilk240 mLwater250 mLice chips200 mLIV infusion60 mL/h × 8 hIV antibiotic1 × 50 mLurine250 mLurine275 mLurine175 mLurine150 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the total intake I in mL. Count ice chips as half their volume.

jelly: 120 mLmilk: 240 mLwater: 250 mLice chips: 200 mLIV infusion: 60 mL/h × 8 hIV antibiotic: 1 × 50 mL
I = mL
8.IV fluids & fluid balanceHard
500 mL100 mL/hstart 12:3014:30: ? mL

Practice exercise (made-up values, not clinical guidance). A 500 mL bag was started at 12:30 and runs by pump at 100 mL/h. How many mL V are left in the bag at 14:30?

500 mL100 mL/h12:30 → 14:30
V = mL
9.Nursing math & unit conversionsMedium
94969810010210410635363738394041°F°C? °F35.7 °C

Practice exercise (made-up values, not clinical guidance). A patient’s temperature is 35.7 °C. Convert it to degrees Fahrenheit T with °F = °C × 9/5 + 32. Round to one decimal place.

35.7 °C
T = °F
10.Nursing math & unit conversionsHard
3 mcg/kg/min? mg/h89 kg1 h = 60 min1 mg = 1000 mcg

Practice exercise (made-up values, not clinical guidance). An order reads 3 mcg/kg/min for a patient who weighs 89 kg. Express the dose rate D in mg/h. Round to two decimal places.

3 mcg/kg/min89 kg
D = mg/h

3Solutions

1.Dosage calculations

Answer: V = 6 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Dose from body weight

D = 5·30 = 150 mg

Volume

V = 150/25 = 6 mL

On the syringe

On this 10 mL syringe every small line is 0.2 mL.

Answer

V = 6 mL
2.Dosage calculations

Answer: V = 0.5 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Same units

0.25 mg = 250 mcg

Volume

V = 250/500 = 0.5 mL

Answer

V = 0.5 mL
3.IV infusion rates

Answer: R = 14 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

12·60 = 720 min

Drip rate

R = 500·20/720 = 13.89 ≈ 14 gtt/min

Answer

R = 14 gtt/min

At the bedside you round to the nearest whole drop: 14 gtt/min.

4.IV infusion rates

Answer: R = 60 gtt/min

Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).

Concentration

1000/250 = 4 mg/mL

Volume per hour

240/4 = 60 mL/h

Drip rate

R = 60·60/60 = 60 gtt/min

Answer

R = 60 gtt/min
5.Pediatric & critical-care dosing

Answer: R = 14.6 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

15·97 = 1 455 units/h

Concentration

25 000/250 = 100 units/mL

Pump rate

R = 1455/100 = 14.55 ≈ 14.6 mL/h

Answer

R = 14.6 mL/h
6.Pediatric & critical-care dosing

Answer: D = 9 mcg/kg/min

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

800 000/500 = 1600 mcg/mL

Micrograms per minute

23·1600 = 36800 mcg/h
36800/60 = 613.3 mcg/min

Per kilogram

D = 613.3/68 = 9.02 ≈ 9 mcg/kg/min

Answer

D = 9 mcg/kg/min
7.IV fluids & fluid balance

Answer: I = 1240 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Add the intake

oral: 120 + 240 + 250 = 610 mL
ice chips: 200/2 = 100 mL
IV infusion: 60·8 = 480 mL
IV antibiotic: 1·50 = 50 mL
I = 1240 mL

Answer

I = 1240 mL
8.IV fluids & fluid balance

Answer: V = 300 mL

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Elapsed time

12:30 → 14:30 = 2 h

Volume infused

100·2 = 200 mL

Volume left

V = 500 − 200 = 300 mL

Answer

V = 300 mL
9.Nursing math & unit conversions

Answer: T = 96.3 °F

Temperature: °C = (°F − 32) × 5/9 and °F = °C × 9/5 + 32. Subtract 32 before you multiply when going from °F, and add 32 after you multiply when going from °C. A quick check: 37 °C is 98.6 °F, and every 1 °C is 1.8 °F.

Multiply by 9/5

35.7·9/5 = 64.26

Add 32

T = 64.26 + 32 = 96.26 ≈ 96.3 °F

Answer

T = 96.3 °F
10.Nursing math & unit conversions

Answer: D = 16.02 mg/h

Dimensional analysis: write the given quantity, then multiply by conversion factors written as fractions (for example 60 min/1 h or 1 mg/1000 mcg) so that each unwanted unit appears once on top and once underneath and cancels. When only the wanted unit is left, calculate. Use the equivalents the question gives and round only the final answer.

Set up the chain

D = 3 mcg/kg/min × 89 kg × (60 min/1 h) × (1 mg/1000 mcg)

Calculate

D = 3·89·60/1000 = 16.02 mg/h

Answer

D = 16.02 mg/h

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