NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
30 kg25 mg/kgD = ? mg

A patient weighs 30 kg and is prescribed 25 mg/kg as a single dose. Find the dose D in mg.

30 kg25 mg/kg
D = mg
2.Dosage calculationsHard
200 mg/5 mLV = ? mL

A child weighing 18 kg is prescribed 12.5 mg/kg per dose of an oral suspension that contains 200 mg in 5 mL. What volume V do you give? Round to one decimal place.

18 kg12.5 mg/kg200 mg/5 mL
V = mL
3.IV infusion ratesMedium
1500 mL20 gtt/mL8 h? gtt/min

Infuse 1500 mL over 8 hours with a giving set of 20 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.

1500 mL8 h20 gtt/mL
R = gtt/min
4.IV infusion ratesHard
1000 mg250 mL15 gtt/mL160 mg/h? gtt/min

1000 mg of a drug is diluted in 250 mL and given by gravity through a set of 15 gtt/mL. The order is 160 mg per hour. Find the drip rate R in drops per minute.

1000 mg/250 mL160 mg/h15 gtt/mL
R = gtt/min
5.Pediatric & critical-care dosingMedium
25 000 units500 mLheparin? mL/h98 kg15 units/kg/h

Practice exercise (made-up values, not clinical guidance). A bag contains 25 000 units of heparin in 500 mL. The order is 15 units/kg/h for a patient who weighs 98 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

25 000 units/500 mL15 units/kg/h98 kg
R = mL/h
6.Pediatric & critical-care dosingHard
25 mg250 mLnitroglycerin? mL/h72 kg20 mcg/min

Practice exercise (made-up values, not clinical guidance). A patient who weighs 72 kg has an order for nitroglycerin at 20 mcg/min. The bag contains 25 mg in 250 mL. Find the pump rate R in mL/h. Round to one decimal place.

25 mg/250 mL20 mcg/min72 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput12-hour shiftsoup200 mLjelly120 mLjuice200 mLIV infusion75 mL/h × 12 hIV antibiotic2 × 100 mLurine175 mLurine350 mLwound drain50 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The patient weighs 90 kg. Find the average urine output U in mL/kg/h. Round to two decimal places.

90 kg12 hurine: 175 mLurine: 350 mLwound drain: 50 mL
U = mL/kg/h
8.IV fluids & fluid balanceHard
1000 mL80 mL/hstart 10:1516:45: ? mL

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag was started at 10:15 and runs by pump at 80 mL/h. How many mL V are left in the bag at 16:45?

1000 mL80 mL/h10:15 → 16:45
V = mL
9.Nursing math & unit conversionsMedium
5 ft 1 in1 ft = 12 in1 in = 2.54 cmh = ? cm

Practice exercise (made-up values, not clinical guidance). A patient is 5 ft 1 in tall. Using 1 ft = 12 in and 1 in = 2.54 cm, find the height h in centimetres, to the nearest whole centimetre.

5 ft 1 in1 ft = 12 in1 in = 2.54 cm
h = cm
10.Nursing math & unit conversionsHard
10 mg/h? mcg/min1 mg = 1000 mcg1 h = 60 min

Practice exercise (made-up values, not clinical guidance). An infusion delivers 10 mg/h. Express this dose rate D in mcg/min. Round to one decimal place.

10 mg/h1 mg = 1000 mcg1 h = 60 min
D = mcg/min

3Solutions

1.Dosage calculations

Answer: D = 750 mg

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Dose

25·30 = 750 mg

Answer

D = 750 mg
2.Dosage calculations

Answer: V = 5.6 mL

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Dose from weight

12.5·18 = 225 mg

Volume

V = (225/200)·5 = 5.625 ≈ 5.6 mL

Answer

V = 5.6 mL
3.IV infusion rates

Answer: R = 63 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

8·60 = 480 min

Drip rate

R = 1500·20/480 = 62.5 ≈ 63 gtt/min

Answer

R = 63 gtt/min

At the bedside you round to the nearest whole drop: 63 gtt/min.

4.IV infusion rates

Answer: R = 10 gtt/min

Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).

Concentration

1000/250 = 4 mg/mL

Volume per hour

160/4 = 40 mL/h

Drip rate

R = 40·15/60 = 10 gtt/min

Answer

R = 10 gtt/min
5.Pediatric & critical-care dosing

Answer: R = 29.4 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

15·98 = 1 470 units/h

Concentration

25 000/500 = 50 units/mL

Pump rate

R = 1470/50 = 29.4 mL/h

Answer

R = 29.4 mL/h
6.Pediatric & critical-care dosing

Answer: R = 12 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

25 000/250 = 100 mcg/mL

Dose per hour

The order is per minute for the whole patient, so the weight is not needed.

20·60 = 1200 mcg/h

Pump rate

R = 1200/100 = 12 mL/h

Answer

R = 12 mL/h
7.IV fluids & fluid balance

Answer: U = 0.49 mL/kg/h

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total urine

175 + 350 = 525 mL

Per kilogram per hour

U = 525/(90·12) = 0.4861 ≈ 0.49 mL/kg/h

Answer

U = 0.49 mL/kg/h
8.IV fluids & fluid balance

Answer: V = 480 mL

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Elapsed time

10:15 → 16:45 = 6.5 h

Volume infused

80·6.5 = 520 mL

Volume left

V = 1000 − 520 = 480 mL

Answer

V = 480 mL
9.Nursing math & unit conversions

Answer: h = 155 cm

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Height in inches

5·12 + 1 = 61 in

Inches to centimetres

h = 61·2.54 = 154.9 ≈ 155 cm

Answer

h = 155 cm
10.Nursing math & unit conversions

Answer: D = 166.7 mcg/min

Dimensional analysis: write the given quantity, then multiply by conversion factors written as fractions (for example 60 min/1 h or 1 mg/1000 mcg) so that each unwanted unit appears once on top and once underneath and cancels. When only the wanted unit is left, calculate. Use the equivalents the question gives and round only the final answer.

Set up the chain

D = 10 mg/h × (1000 mcg/1 mg) × (1 h/60 min)

Calculate

D = 10000/60 = 166.7 mcg/min

Answer

D = 166.7 mcg/min

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