NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
024681010 mL

A child weighing 19 kg is prescribed 5 mg/kg of a drug. The stock solution contains 25 mg/mL. Draw up the dose: what volume V do you give?

19 kg5 mg/kg25 mg/mL
V = mL
2.Dosage calculationsHard
00.10.20.30.40.50.60.70.80.911 mL

The prescription is 285 micrograms. The ampoule contains 0.5 mg/mL. Draw up the dose in the 1 mL syringe: what volume V do you give?

285 mcg0.5 mg/mL
V = mL
3.IV infusion ratesMedium
V = ?20 gtt/mL30 gtt/min8 h

A drip runs at 30 gtt/min through a set of 20 gtt/mL. How many millilitres V does the patient receive in 8 hours?

30 gtt/min20 gtt/mL8 h
V = mL
4.IV infusion ratesHard
1000 mg500 mL60 gtt/mL150 mg/h? gtt/min

1000 mg of a drug is diluted in 500 mL and given by gravity through a set of 60 gtt/mL. The order is 150 mg per hour. Find the drip rate R in drops per minute.

1000 mg/500 mL150 mg/h60 gtt/mL
R = gtt/min
5.Pediatric & critical-care dosingMedium
20 000 units500 mLheparin? mL/h89 kg18 units/kg/h

Practice exercise (made-up values, not clinical guidance). A bag contains 20 000 units of heparin in 500 mL. The order is 18 units/kg/h for a patient who weighs 89 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

20 000 units/500 mL18 units/kg/h89 kg
R = mL/h
6.Pediatric & critical-care dosingHard
500 mg250 mLdobutamine23 mL/h88 kg? mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A dobutamine infusion of 500 mg in 250 mL runs at 23 mL/h. The patient weighs 88 kg. What dose D in mcg/kg/min is the patient receiving? Round to one decimal place.

500 mg/250 mL23 mL/h88 kg
D = mcg/kg/min
7.IV fluids & fluid balanceMedium
IntakeOutput12-hour shiftjuice120 mLjelly120 mLIV infusion60 mL/h × 12 hIV antibiotic1 × 100 mLurine300 mLurine475 mLurine225 mLvomit150 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the fluid balance B = intake − output in mL (a negative answer means a net loss).

juice: 120 mLjelly: 120 mLIV infusion: 60 mL/h × 12 hIV antibiotic: 1 × 100 mLurine: 300 mLurine: 475 mLurine: 225 mLvomit: 150 mL
B = mL
8.IV fluids & fluid balanceHard
1000 mL80 mL/hstart 07:3011:30: ? mL

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag was started at 07:30 and runs by pump at 80 mL/h. How many mL V are left in the bag at 11:30?

1000 mL80 mL/h07:30 → 11:30
V = mL
9.Nursing math & unit conversionsMedium
94969810010210410635363738394041°F°C102.4 °F? °C

Practice exercise (made-up values, not clinical guidance). A patient’s temperature is 102.4 °F. Convert it to degrees Celsius T with °C = (°F − 32) × 5/9. Round to one decimal place.

102.4 °F
T = °C
10.Nursing math & unit conversionsHard
2 cups? mL½ tbsp? mL½ fl oz? mL1 tsp? mLΣ = ? mL

Practice exercise (made-up values, not clinical guidance). During a shift a patient takes 2 cups of tea, ½ tbsp of liquid supplement, ½ fl oz of juice, 1 tsp of cough syrup. Using the equivalents given, find the total oral intake V in mL.

1 cup = 8 fl oz = 240 mL1 tbsp = 15 mL1 fl oz = 30 mL1 tsp = 5 mL
V = mL

3Solutions

1.Dosage calculations

Answer: V = 3.8 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Dose from body weight

D = 5·19 = 95 mg

Volume

V = 95/25 = 3.8 mL

On the syringe

On this 10 mL syringe every small line is 0.2 mL.

Answer

V = 3.8 mL
2.Dosage calculations

Answer: V = 0.57 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Same units

0.5 mg/mL = 500 mcg/mL

Volume

V = 285/500 = 0.57 mL

Answer

V = 0.57 mL
3.IV infusion rates

Answer: V = 720 mL

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

30·60/20 = 90 mL/h

Volume

V = 90·8 = 720 mL

Answer

V = 720 mL
4.IV infusion rates

Answer: R = 75 gtt/min

Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).

Concentration

1000/500 = 2 mg/mL

Volume per hour

150/2 = 75 mL/h

Drip rate

R = 75·60/60 = 75 gtt/min

Answer

R = 75 gtt/min
5.Pediatric & critical-care dosing

Answer: R = 40.1 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

18·89 = 1 602 units/h

Concentration

20 000/500 = 40 units/mL

Pump rate

R = 1602/40 = 40.05 ≈ 40.1 mL/h

Answer

R = 40.1 mL/h
6.Pediatric & critical-care dosing

Answer: D = 8.7 mcg/kg/min

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

500 000/250 = 2000 mcg/mL

Micrograms per minute

23·2000 = 46000 mcg/h
46000/60 = 766.7 mcg/min

Per kilogram

D = 766.7/88 = 8.712 ≈ 8.7 mcg/kg/min

Answer

D = 8.7 mcg/kg/min
7.IV fluids & fluid balance

Answer: B = −90 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total intake

oral: 120 + 120 = 240 mL
IV infusion: 60·12 = 720 mL
IV antibiotic: 1·100 = 100 mL
total intake = 1060 mL

Total output

300 + 475 + 225 + 150 = 1150 mL

Balance

B = 1060 − 1150 = −90 mL

Answer

B = −90 mL

Negative: the patient lost more fluid than went in.

8.IV fluids & fluid balance

Answer: V = 680 mL

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Elapsed time

07:30 → 11:30 = 4 h

Volume infused

80·4 = 320 mL

Volume left

V = 1000 − 320 = 680 mL

Answer

V = 680 mL
9.Nursing math & unit conversions

Answer: T = 39.1 °C

Temperature: °C = (°F − 32) × 5/9 and °F = °C × 9/5 + 32. Subtract 32 before you multiply when going from °F, and add 32 after you multiply when going from °C. A quick check: 37 °C is 98.6 °F, and every 1 °C is 1.8 °F.

Subtract 32

102.4 − 32 = 70.4

Multiply by 5/9

T = 70.4·5/9 = 39.11 ≈ 39.1 °C

Answer

T = 39.1 °C
10.Nursing math & unit conversions

Answer: V = 507.5 mL

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Each item in mL

2 cups = 2·240 = 480 mL
½ tbsp = 0.5·15 = 7.5 mL
½ fl oz = 0.5·30 = 15 mL
1 tsp = 1·5 = 5 mL

Add

V = 480 + 7.5 + 15 + 5 = 507.5 mL

Answer

V = 507.5 mL

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