NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
12 kg30 mg/kgD = ? mg

A patient weighs 12 kg and is prescribed 30 mg/kg as a single dose. Find the dose D in mg.

12 kg30 mg/kg
D = mg
2.Dosage calculationsHard
40 mg/1 mLV = ? mL

A patient weighs 149.6 lb. The prescription is 10 mg/kg as a single dose, and the stock contains 40 mg in 1 mL. Using 1 kg = 2.2 lb, what volume V do you give?

149.6 lb10 mg/kg40 mg/1 mL1 kg = 2.2 lb
V = mL
3.IV infusion ratesMedium
220 mLleft? mL/h4 h left

500 mL was ordered over 10 hours. After 6 hours you find that 220 mL is still in the bag, and the order must still finish on time. To what rate R in mL/h must the pump be reset?

500 mL / 10 hafter 6 h: 220 mL
R = mL/h
4.IV infusion ratesHard
500 mg500 mL20 gtt/mL75 mg/h? gtt/min

500 mg of a drug is diluted in 500 mL and given by gravity through a set of 20 gtt/mL. The order is 75 mg per hour. Find the drip rate R in drops per minute.

500 mg/500 mL75 mg/h20 gtt/mL
R = gtt/min
5.Pediatric & critical-care dosingMedium
250 units250 mLregular insulin? mL/h96 kg0.05 units/kg/h

Practice exercise (made-up values, not clinical guidance). An infusion contains 250 units of regular insulin in 250 mL. The order is 0.05 units/kg/h for a patient who weighs 96 kg. Find the pump rate R in mL/h. Round to one decimal place.

250 units/250 mL0.05 units/kg/h96 kg
R = mL/h
6.Pediatric & critical-care dosingHard
50 mg250 mLnitroglycerin? mL/h97 kg20 mcg/min

Practice exercise (made-up values, not clinical guidance). A patient who weighs 97 kg has an order for nitroglycerin at 20 mcg/min. The bag contains 50 mg in 250 mL. Find the pump rate R in mL/h. Round to one decimal place.

50 mg/250 mL20 mcg/min97 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftjuice200 mLsoup250 mLtea150 mLice chips240 mLIV infusion60 mL/h × 8 hIV antibiotic1 × 100 mLurine450 mLurine350 mLurine300 mLwound drain80 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The patient weighs 58 kg. Find the average urine output U in mL/kg/h. Round to two decimal places.

58 kg8 hurine: 450 mLurine: 350 mLurine: 300 mLwound drain: 80 mL
U = mL/kg/h
8.IV fluids & fluid balanceHard
1000 mL80 mL/hstart 11:1517:45: ? mL

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag was started at 11:15 and runs by pump at 80 mL/h. How many mL V are left in the bag at 17:45?

1000 mL80 mL/h11:15 → 17:45
V = mL
9.Nursing math & unit conversionsMedium
12345678910111208:30?7:30 AM10:30 AM8:30 PM8:30 AM

Practice exercise (made-up values, not clinical guidance). A dose is charted at 08:30 (24-hour clock). Which entry is the same time on the 12-hour clock? Click it.

08:30
  1. 17:30 AM
  2. 210:30 AM
  3. 38:30 PM
  4. 48:30 AM
10.Nursing math & unit conversionsHard
3 tsp? mL¼ cup? mL2 tbsp? mLΣ = ? mL

Practice exercise (made-up values, not clinical guidance). During a shift a patient takes 3 tsp of cough syrup, ¼ cup of tea, 2 tbsp of liquid supplement. Using the equivalents given, find the total oral intake V in mL.

1 tsp = 5 mL1 cup = 8 fl oz = 240 mL1 tbsp = 15 mL
V = mL

3Solutions

1.Dosage calculations

Answer: D = 360 mg

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Dose

30·12 = 360 mg

Answer

D = 360 mg
2.Dosage calculations

Answer: V = 17 mL

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Weight in kg

149.6/2.2 = 68 kg

Dose

10·68 = 680 mg

Volume

V = (680/40)·1 = 17 mL

Answer

V = 17 mL
3.IV infusion rates

Answer: R = 55 mL/h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Original rate

500/10 = 50 mL/h

New rate

R = 220/4 = 55 mL/h

Answer

R = 55 mL/h

Many hospitals allow such an adjustment up to 25% without a new order; check local policy.

4.IV infusion rates

Answer: R = 25 gtt/min

Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).

Concentration

500/500 = 1 mg/mL

Volume per hour

75/1 = 75 mL/h

Drip rate

R = 75·20/60 = 25 gtt/min

Answer

R = 25 gtt/min
5.Pediatric & critical-care dosing

Answer: R = 4.8 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

0.05·96 = 4.8 units/h

Concentration

250/250 = 1 units/mL

Pump rate

R = 4.8/1 = 4.8 mL/h

Answer

R = 4.8 mL/h
6.Pediatric & critical-care dosing

Answer: R = 6 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

50 000/250 = 200 mcg/mL

Dose per hour

The order is per minute for the whole patient, so the weight is not needed.

20·60 = 1200 mcg/h

Pump rate

R = 1200/200 = 6 mL/h

Answer

R = 6 mL/h
7.IV fluids & fluid balance

Answer: U = 2.37 mL/kg/h

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total urine

450 + 350 + 300 = 1100 mL

Per kilogram per hour

U = 1100/(58·8) = 2.371 ≈ 2.37 mL/kg/h

Answer

U = 2.37 mL/kg/h
8.IV fluids & fluid balance

Answer: V = 480 mL

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Elapsed time

11:15 → 17:45 = 6.5 h

Volume infused

80·6.5 = 520 mL

Volume left

V = 1000 − 520 = 480 mL

Answer

V = 480 mL
9.Nursing math & unit conversions

Answer: 8:30 AM

24-hour clock: from 1 PM onwards add 12 to the hour (3:45 PM = 15:45). Midnight to 12:59 AM is 00:00–00:59, and 12:00–12:59 PM stays 12:00–12:59. Going back, subtract 12 from hours 13–23 and add PM; hours 00 become 12 AM. Count time across midnight in two parts: up to 24:00 (00:00), then from 00:00 on.

Convert the hour

08 → 8 AM

Answer

8:30 AM

Answer

8:30 AM
10.Nursing math & unit conversions

Answer: V = 105 mL

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Each item in mL

3 tsp = 3·5 = 15 mL
¼ cup = 0.25·240 = 60 mL
2 tbsp = 2·15 = 30 mL

Add

V = 15 + 60 + 30 = 105 mL

Answer

V = 105 mL

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