NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
12 kg30 mg/kgD = ? mg

A patient weighs 12 kg and is prescribed 30 mg/kg as a single dose. Find the dose D in mg.

12 kg30 mg/kg
D = mg
2.Dosage calculationsHard
40 mg/1 mLV = ? mL

A patient weighs 134.2 lb. The prescription is 5 mg/kg as a single dose, and the stock contains 40 mg in 1 mL. Using 1 kg = 2.2 lb, what volume V do you give? Round to one decimal place.

134.2 lb5 mg/kg40 mg/1 mL1 kg = 2.2 lb
V = mL
3.IV infusion ratesMedium
60 gtt/mL80 mL/h? gtt/min

An infusion is ordered at 80 mL/h, but no pump is available. It runs by gravity through a giving set of 60 gtt/mL. Find the drip rate R in drops per minute.

80 mL/h60 gtt/mL
R = gtt/min
4.IV infusion ratesHard
750 mL15 gtt/mL32 gtt/mint = ? h

A drip runs at 32 gtt/min through a set of 15 gtt/mL. There are 750 mL left in the bag. How many hours t until it is empty? Round to one decimal place.

32 gtt/min15 gtt/mL750 mL
t = h
5.Pediatric & critical-care dosingMedium
12 500 units250 mLheparin? mL/h60 kg16 units/kg/h

Practice exercise (made-up values, not clinical guidance). A bag contains 12 500 units of heparin in 250 mL. The order is 16 units/kg/h for a patient who weighs 60 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

12 500 units/250 mL16 units/kg/h60 kg
R = mL/h
6.Pediatric & critical-care dosingHard
400 mg250 mLdopamine33 mL/h94 kg? mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A dopamine infusion of 400 mg in 250 mL runs at 33 mL/h. The patient weighs 94 kg. What dose D in mcg/kg/min is the patient receiving? Round to one decimal place.

400 mg/250 mL33 mL/h94 kg
D = mcg/kg/min
7.IV fluids & fluid balanceMedium
IntakeOutput12-hour shiftjelly100 mLmilk240 mLtea200 mLIV infusion50 mL/h × 12 hIV antibiotic1 × 50 mLurine400 mLurine200 mLurine350 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The patient weighs 93 kg. Find the average urine output U in mL/kg/h. Round to two decimal places.

93 kg12 hurine: 400 mLurine: 200 mLurine: 350 mL
U = mL/kg/h
8.IV fluids & fluid balanceHard
500 mL150 mL infused60 mL/h07:00t = ? h

Practice exercise (made-up values, not clinical guidance). A 500 mL bag runs by pump at 60 mL/h. At 07:00, 150 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

500 mL150 mL infused60 mL/h
t = h
9.Nursing math & unit conversionsMedium
94969810010210410635363738394041°F°C? °F38 °C

Practice exercise (made-up values, not clinical guidance). A patient’s temperature is 38 °C. Convert it to degrees Fahrenheit T with °F = °C × 9/5 + 32. Round to one decimal place.

38 °C
T = °F
10.Nursing math & unit conversionsHard
00:0020:2506:50t = ?

Practice exercise (made-up values, not clinical guidance). An infusion starts at 20:25 and finishes at 06:50 the next morning (24-hour clock). How many hours t did it run? Give the answer in hours as a decimal, rounded to two decimal places.

20:2506:50
t = h

3Solutions

1.Dosage calculations

Answer: D = 360 mg

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Dose

30·12 = 360 mg

Answer

D = 360 mg
2.Dosage calculations

Answer: V = 7.6 mL

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Weight in kg

134.2/2.2 = 61 kg

Dose

5·61 = 305 mg

Volume

V = (305/40)·1 = 7.625 ≈ 7.6 mL

Answer

V = 7.6 mL
3.IV infusion rates

Answer: R = 80 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Millilitres per minute

80/60 = 1.333 mL/min

Drip rate

R = 1.333·60 = 80 gtt/min

Answer

R = 80 gtt/min

With a microdrip set (60 gtt/mL), gtt/min equals mL/h.

4.IV infusion rates

Answer: t = 5.9 h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

32·60/15 = 128 mL/h

Time left

t = 750/128 = 5.859 ≈ 5.9 h

Answer

t = 5.9 h
5.Pediatric & critical-care dosing

Answer: R = 19.2 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

16·60 = 960 units/h

Concentration

12 500/250 = 50 units/mL

Pump rate

R = 960/50 = 19.2 mL/h

Answer

R = 19.2 mL/h
6.Pediatric & critical-care dosing

Answer: D = 9.4 mcg/kg/min

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

400 000/250 = 1600 mcg/mL

Micrograms per minute

33·1600 = 52800 mcg/h
52800/60 = 880 mcg/min

Per kilogram

D = 880/94 = 9.362 ≈ 9.4 mcg/kg/min

Answer

D = 9.4 mcg/kg/min
7.IV fluids & fluid balance

Answer: U = 0.85 mL/kg/h

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total urine

400 + 200 + 350 = 950 mL

Per kilogram per hour

U = 950/(93·12) = 0.8513 ≈ 0.85 mL/kg/h

Answer

U = 0.85 mL/kg/h
8.IV fluids & fluid balance

Answer: t = 5.8 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

500 − 150 = 350 mL

Time

t = 350/60 = 5.833 ≈ 5.8 h

Answer

t = 5.8 h

That is about 5 h 50 min, so the bag runs out at about 12:50.

9.Nursing math & unit conversions

Answer: T = 100.4 °F

Temperature: °C = (°F − 32) × 5/9 and °F = °C × 9/5 + 32. Subtract 32 before you multiply when going from °F, and add 32 after you multiply when going from °C. A quick check: 37 °C is 98.6 °F, and every 1 °C is 1.8 °F.

Multiply by 9/5

38·9/5 = 68.4

Add 32

T = 68.4 + 32 = 100.4 °F

Answer

T = 100.4 °F
10.Nursing math & unit conversions

Answer: t = 10.42 h

24-hour clock: from 1 PM onwards add 12 to the hour (3:45 PM = 15:45). Midnight to 12:59 AM is 00:00–00:59, and 12:00–12:59 PM stays 12:00–12:59. Going back, subtract 12 from hours 13–23 and add PM; hours 00 become 12 AM. Count time across midnight in two parts: up to 24:00 (00:00), then from 00:00 on.

Before midnight

20:25 → 24:00 = 215 min

After midnight

00:00 → 06:50 = 410 min

Total

215 + 410 = 625 min
t = 625/60 = 10.42 h

Answer

t = 10.42 h

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