NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
024681010 mL

A child weighing 20 kg is prescribed 7.5 mg/kg of a drug. The stock solution contains 50 mg/mL. Draw up the dose: what volume V do you give?

20 kg7.5 mg/kg50 mg/mL
V = mL
2.Dosage calculationsHard
125 mg/5 mLV = ? mL

A child weighing 10 kg is prescribed 5 mg/kg per dose of an oral suspension that contains 125 mg in 5 mL. What volume V do you give?

10 kg5 mg/kg125 mg/5 mL
V = mL
3.IV infusion ratesMedium
V = ?20 gtt/mL30 gtt/min12 h

A drip runs at 30 gtt/min through a set of 20 gtt/mL. How many millilitres V does the patient receive in 12 hours?

30 gtt/min20 gtt/mL12 h
V = mL
4.IV infusion ratesHard
100 mg100 mL15 mL/h? mg/h

A bag contains 100 mg of a drug in 100 mL and runs at 15 mL/h. How many milligrams per hour D does the patient receive?

100 mg/100 mL15 mL/h
D = mg/h
5.Pediatric & critical-care dosingMedium
25 000 units250 mLheparin? mL/h70 kg18 units/kg/h

Practice exercise (made-up values, not clinical guidance). A bag contains 25 000 units of heparin in 250 mL. The order is 18 units/kg/h for a patient who weighs 70 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

25 000 units/250 mL18 units/kg/h70 kg
R = mL/h
6.Pediatric & critical-care dosingHard
800 mg500 mLdopamine27 mL/h79 kg? mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A dopamine infusion of 800 mg in 500 mL runs at 27 mL/h. The patient weighs 79 kg. What dose D in mcg/kg/min is the patient receiving? Round to one decimal place.

800 mg/500 mL27 mL/h79 kg
D = mcg/kg/min
7.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftjuice200 mLjelly100 mLwater350 mLice chips120 mLIV infusion125 mL/h × 8 hIV antibiotic1 × 100 mLurine350 mLurine325 mLurine375 mLwound drain80 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The patient weighs 62 kg. Find the average urine output U in mL/kg/h. Round to two decimal places.

62 kg8 hurine: 350 mLurine: 325 mLurine: 375 mLwound drain: 80 mL
U = mL/kg/h
8.IV fluids & fluid balanceHard
1000 mL650 mL infused120 mL/h10:00t = ? h

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag runs by pump at 120 mL/h. At 10:00, 650 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

1000 mL650 mL infused120 mL/h
t = h
9.Nursing math & unit conversionsMedium
0.43599 mL? mLround to 0.01 mL

Practice exercise (made-up values, not clinical guidance). A dose calculation for a small injection gives 0.43599 mL. The rule in this exercise is that volumes below 1 mL are rounded to the nearest hundredth of a mL. What value x do you record?

0.43599 mL
x = mL
10.Nursing math & unit conversionsHard
2 tsp · 2/day · 7 d? mL1 tsp = 5 mL

Practice exercise (made-up values, not clinical guidance). A prescription reads 2 tsp of an oral suspension every 12 hours for 7 days. Using 1 tsp = 5 mL, how many mL V are needed for the whole course?

2 tspevery 12 hours7 days1 tsp = 5 mL
V = mL

3Solutions

1.Dosage calculations

Answer: V = 3 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Dose from body weight

D = 7.5·20 = 150 mg

Volume

V = 150/50 = 3 mL

On the syringe

On this 10 mL syringe every small line is 0.2 mL.

Answer

V = 3 mL
2.Dosage calculations

Answer: V = 2 mL

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Dose from weight

5·10 = 50 mg

Volume

V = (50/125)·5 = 2 mL

Answer

V = 2 mL
3.IV infusion rates

Answer: V = 1080 mL

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

30·60/20 = 90 mL/h

Volume

V = 90·12 = 1080 mL

Answer

V = 1080 mL
4.IV infusion rates

Answer: D = 15 mg/h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Concentration

100/100 = 1 mg/mL

Dose rate

D = 1·15 = 15 mg/h

Answer

D = 15 mg/h
5.Pediatric & critical-care dosing

Answer: R = 12.6 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Units per hour

18·70 = 1 260 units/h

Concentration

25 000/250 = 100 units/mL

Pump rate

R = 1260/100 = 12.6 mL/h

Answer

R = 12.6 mL/h
6.Pediatric & critical-care dosing

Answer: D = 9.1 mcg/kg/min

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

800 000/500 = 1600 mcg/mL

Micrograms per minute

27·1600 = 43200 mcg/h
43200/60 = 720 mcg/min

Per kilogram

D = 720/79 = 9.114 ≈ 9.1 mcg/kg/min

Answer

D = 9.1 mcg/kg/min
7.IV fluids & fluid balance

Answer: U = 2.12 mL/kg/h

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total urine

350 + 325 + 375 = 1050 mL

Per kilogram per hour

U = 1050/(62·8) = 2.117 ≈ 2.12 mL/kg/h

Answer

U = 2.12 mL/kg/h
8.IV fluids & fluid balance

Answer: t = 2.9 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

1000 − 650 = 350 mL

Time

t = 350/120 = 2.917 ≈ 2.9 h

Answer

t = 2.9 h

That is about 2 h 55 min, so the bag runs out at about 12:55.

9.Nursing math & unit conversions

Answer: x = 0.44 mL

Rounding: look at the digit just after the place you round to: 5 or more rounds up, 4 or less leaves the digit as it is. Round only the final answer, never the steps. Typical exam rules: volumes of 1 mL or more to the nearest tenth, volumes below 1 mL to the nearest hundredth, drip rates to whole drops and weights to one decimal place; always follow the rule the question states.

Digit in the hundredths place

0.43599 → 3

Only the next digit decides

0.43599 → 5
5 is 5 or more, so round 3 up.
The digits after it (99) are ignored: round once, never step by step.

Round

x = 0.44 mL

Answer

x = 0.44 mL
10.Nursing math & unit conversions

Answer: V = 140 mL

Dimensional analysis: write the given quantity, then multiply by conversion factors written as fractions (for example 60 min/1 h or 1 mg/1000 mcg) so that each unwanted unit appears once on top and once underneath and cancels. When only the wanted unit is left, calculate. Use the equivalents the question gives and round only the final answer.

Volume per dose

2 tsp = 2·5 = 10 mL

Whole course

V = 10 mL × 2/day × 7 = 140 mL

Answer

V = 140 mL

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