NCLEX-style dosage calculations: cram pack

Formula sheets, the key method steps for every topic and 10 practice problems, with full solutions at the back.

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1Formulas and methods

Dosage calculations

Dose from strength
volume = dose / strength
Weight-based dose
dose = mg/kg × body weight
Tablets
number = dose / tablet strength
Units
1 g = 1000 mg, 1 mg = 1000 mcg

Method

  1. Convert the ordered dose and the stock strength to the same unit.
  2. Use desired over have times quantity: (D/H) × Q.
  3. For weight-based doses, multiply by the weight in kg first, then divide the daily dose by the number of doses.
  4. Estimate first and check that the answer is reasonable.

IV infusion rates

Pump rate
mL/h = volume (mL)/time (h)
Drip rate
drops/min = volume (mL) × drop factor / time (min)
Infusion time
time (h) = volume (mL)/rate (mL/h)

Method

  1. Pump rate in mL/h: volume divided by time in hours.
  2. Drip rate in drops/min: volume × drop factor divided by time in minutes.
  3. For time remaining: volume left divided by the rate.
  4. Round as the question or the equipment requires.

Pediatric & critical-care dosing

Daily dose
mg/day = mg/kg/day × weight (kg)
Doses per day
number = 24 h / dosing interval (h)
Pounds to kilograms
kg = lb / 2.2
Infusion concentration
units/mL = units in bag / bag volume
Pump rate
mL/h = dose per hour / concentration
Titrated drip
mL/h = mcg/kg/min × kg × 60 / (mcg/mL)
Dose from pump rate
mcg/kg/min = mL/h × (mcg/mL) / (60 × kg)
Units
1 mg = 1000 mcg

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

Nursing math & unit conversions

Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
Temperature
°C = (°F − 32)·5/9, °F = °C·9/5 + 32
24-hour clock
PM hours 1–11: add 12; 12 AM = 00:xx; 12 PM = 12:xx
Dose rate
mcg/min × 60/1000 = mg/h
Laboratory factors
glucose 1 mmol/L = 18 mg/dL; creatinine 1 mg/dL = 88.4 µmol/L; Hb 1 g/dL = 10 g/L

Method

  1. Write the given quantity with its unit and the unit you want.
  2. Pick the equivalent: 1000 between kg, g, mg and mcg or L and mL; 1 kg = 2.2 lb; 1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 240 mL.
  3. Write it as a fraction so that the unwanted unit cancels; for a rate, use one fraction per unit that changes.
  4. Check the direction: a smaller unit gives a bigger number.
  5. Round only the final answer, to the precision the question names.

2Practice problems

1.Dosage calculationsMedium
024681010 mL

A child weighing 27 kg is prescribed 2 mg/kg of a drug. The stock solution contains 10 mg/mL. Draw up the dose: what volume V do you give?

27 kg2 mg/kg10 mg/mL
V = mL
2.Dosage calculationsHard
20k units1000 mL? mL/h1200 units/h

An infusion contains 20000 units of a drug in 1000 mL. The prescription is 1200 units per hour. At what rate R do you set the pump, in mL/h?

20000 units/1000 mL1200 units/h
R = mL/h
3.IV infusion ratesMedium
250 mL20 gtt/mL5 h? gtt/min

Infuse 250 mL over 5 hours with a giving set of 20 gtt/mL. Find the drip rate R in drops per minute. Round to the nearest whole number.

250 mL5 h20 gtt/mL
R = gtt/min
4.IV infusion ratesHard
900 mL20 gtt/mL42 gtt/mint = ? h

A drip runs at 42 gtt/min through a set of 20 gtt/mL. There are 900 mL left in the bag. How many hours t until it is empty? Round to one decimal place.

42 gtt/min20 gtt/mL900 mL
t = h
5.Pediatric & critical-care dosingMedium
50 units50 mLregular insulin? mL/h6 units/h

Practice exercise (made-up values, not clinical guidance). An infusion contains 50 units of regular insulin in 50 mL. The order is 6 units/h. Find the pump rate R in mL/h. Round to one decimal place.

50 units/50 mL6 units/h
R = mL/h
6.Pediatric & critical-care dosingHard
400 mg250 mLdopamine? mL/h62 kg12 mcg/kg/min

Practice exercise (made-up values, not clinical guidance). A bag contains dopamine 400 mg in 250 mL. The order is 12 mcg/kg/min for a patient who weighs 62 kg. At what rate R do you set the pump, in mL/h? Round to one decimal place.

400 mg/250 mL12 mcg/kg/min62 kg
R = mL/h
7.IV fluids & fluid balanceMedium
IntakeOutput12-hour shiftwater350 mLtea150 mLice chips100 mLIV infusion125 mL/h × 12 hIV antibiotic1 × 100 mLurine375 mLurine350 mLurine350 mLurine400 mLwound drain80 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The patient weighs 48 kg. Find the average urine output U in mL/kg/h. Round to two decimal places.

48 kg12 hurine: 375 mLurine: 350 mLurine: 350 mLurine: 400 mLwound drain: 80 mL
U = mL/kg/h
8.IV fluids & fluid balanceHard
1000 mL150 mL infused150 mL/h09:30t = ? h

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag runs by pump at 150 mL/h. At 09:30, 150 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

1000 mL150 mL infused150 mL/h
t = h
9.Nursing math & unit conversionsMedium
94969810010210410635363738394041°F°C102.9 °F? °C

Practice exercise (made-up values, not clinical guidance). A patient’s temperature is 102.9 °F. Convert it to degrees Celsius T with °C = (°F − 32) × 5/9. Round to one decimal place.

102.9 °F
T = °C
10.Nursing math & unit conversionsHard
1 tbsp? mL8 fl oz? mL2 tsp? mL½ cup? mLΣ = ? mL

Practice exercise (made-up values, not clinical guidance). During a shift a patient takes 1 tbsp of liquid supplement, 8 fl oz of juice, 2 tsp of cough syrup, ½ cup of tea. Using the equivalents given, find the total oral intake V in mL.

1 tbsp = 15 mL1 fl oz = 30 mL1 tsp = 5 mL1 cup = 8 fl oz = 240 mL
V = mL

3Solutions

1.Dosage calculations

Answer: V = 5.4 mL

Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.

Dose from body weight

D = 2·27 = 54 mg

Volume

V = 54/10 = 5.4 mL

On the syringe

On this 10 mL syringe every small line is 0.2 mL.

Answer

V = 5.4 mL
2.Dosage calculations

Answer: R = 60 mL/h

Dose calculation: the amount to give equals what is prescribed divided by what you have, times the quantity it comes in: amount = (desired dose/stock strength) × stock volume. Always keep the units the same (convert g to mg, mg to mcg first) and check that the answer is sensible.

Concentration

20000/1000 = 20 units/mL

Pump rate

R = 1200/20 = 60 mL/h

Answer

R = 60 mL/h
3.IV infusion rates

Answer: R = 17 gtt/min

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Time in minutes

5·60 = 300 min

Drip rate

R = 250·20/300 = 16.67 ≈ 17 gtt/min

Answer

R = 17 gtt/min

At the bedside you round to the nearest whole drop: 17 gtt/min.

4.IV infusion rates

Answer: t = 7.1 h

Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.

Rate in mL/h

42·60/20 = 126 mL/h

Time left

t = 900/126 = 7.143 ≈ 7.1 h

Answer

t = 7.1 h
5.Pediatric & critical-care dosing

Answer: R = 6 mL/h

Heparin and insulin infusions: concentration = units in the bag/bag volume (units/mL). Pump rate (mL/h) = units per hour/concentration, and units per hour = mL/h × concentration. For a weight-based order, units/h = units/kg/h × weight first. A bolus volume = units needed/vial strength. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

50/50 = 1 units/mL

Pump rate

R = 6/1 = 6 mL/h

Answer

R = 6 mL/h
6.Pediatric & critical-care dosing

Answer: R = 27.9 mL/h

Titrated drips: first find the concentration in mcg/mL (mg × 1000/mL). For a weight-based order, mcg/min = mcg/kg/min × weight. Then mL/h = mcg/min × 60/concentration. Working backwards, mcg/kg/min = mL/h × concentration/(60 × weight). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Concentration

400 mg = 400 000 mcg
400 000/250 = 1600 mcg/mL

Dose per minute and per hour

12·62 = 744 mcg/min
744·60 = 44640 mcg/h

Pump rate

R = 44640/1600 = 27.9 mL/h

Answer

R = 27.9 mL/h
7.IV fluids & fluid balance

Answer: U = 2.56 mL/kg/h

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total urine

375 + 350 + 350 + 400 = 1475 mL

Per kilogram per hour

U = 1475/(48·12) = 2.561 ≈ 2.56 mL/kg/h

Answer

U = 2.56 mL/kg/h
8.IV fluids & fluid balance

Answer: t = 5.7 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

1000 − 150 = 850 mL

Time

t = 850/150 = 5.667 ≈ 5.7 h

Answer

t = 5.7 h

That is about 5 h 40 min, so the bag runs out at about 15:10.

9.Nursing math & unit conversions

Answer: T = 39.4 °C

Temperature: °C = (°F − 32) × 5/9 and °F = °C × 9/5 + 32. Subtract 32 before you multiply when going from °F, and add 32 after you multiply when going from °C. A quick check: 37 °C is 98.6 °F, and every 1 °C is 1.8 °F.

Subtract 32

102.9 − 32 = 70.9

Multiply by 5/9

T = 70.9·5/9 = 39.39 ≈ 39.4 °C

Answer

T = 39.4 °C
10.Nursing math & unit conversions

Answer: V = 385 mL

Household measures and weight: nursing exams use rounded equivalents: 1 teaspoon (tsp) = 5 mL, 1 tablespoon (tbsp) = 15 mL = 3 tsp, 1 fluid ounce (fl oz) = 30 mL = 2 tbsp, and 1 cup = 8 fl oz = 240 mL. For weight, 1 kg = 2.2 lb and 1 lb = 16 oz; for length, 1 inch = 2.54 cm. Set the conversion up so that the unit you do not want cancels out.

Each item in mL

1 tbsp = 1·15 = 15 mL
8 fl oz = 8·30 = 240 mL
2 tsp = 2·5 = 10 mL
½ cup = 0.5·240 = 120 mL

Add

V = 15 + 240 + 10 + 120 = 385 mL

Answer

V = 385 mL

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