Keep sterile items sterile: if in doubt, it is not sterile; replace, never wipe.
Prevent harm in the environment: fall measures, restraints only as a last resort, RACE and PASS for fire.
Check the rights of medication administration, two identifiers and extra safeguards for high-alert drugs; report errors and near misses.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
Lab values & electrolytes
Method
Compare the value with the laboratory’s own reference range, then with the patient’s baseline and trend.
Check the sample: hemolysis, a delay, or blood drawn near an IV can give false results.
Link the value to its typical signs and to the drugs and conditions that cause it.
Look for interactions: low potassium or magnesium increases digoxin toxicity; dehydration raises lithium.
Act on the patient: assess, hold a drug if the level is unsafe, read back critical values and inform the prescriber.
Med-surg: cardiovascular & respiratory
Method
Name the problem: pump failure, blocked artery, rhythm, clot, airway narrowing, infection or a device problem.
Check the danger signs first: hypoxia, hypotension, chest pain, new confusion, a cold pulseless limb.
Match the oxygen to the patient: 94–98% for most, 88–92% for those at risk of CO₂ retention.
Link each drug to its test and its risk: warfarin and INR, heparin and aPTT and platelets, diuretics and potassium.
Choose the safe first action, then escalate and reassess.
Med-surg: neuro, endocrine & renal
Method
Check the glucose in every patient with new confusion, weakness or a seizure.
Use the level of consciousness as the earliest warning of brain trouble; pupils and Cushing’s triad come late.
For diabetes emergencies, separate DKA (ketones, acidosis) from HHS (very high osmolality, dehydration); give fluids first.
For sodium and water, decide whether ADH is in excess (SIADH) or missing (DI), and correct chronic changes slowly.
For kidney problems, sort the cause into pre-renal, intrinsic or post-renal, and watch potassium and fluid.
Med-surg: GI, perioperative & oncology
Method
Ask what could be hidden: internal bleeding, infection without fever, hypoventilation behind a normal SpO₂.
Use the timing after surgery to narrow the complications: bleeding in hours, chest problems in days, wound and leak problems later.
For pain, assess, treat with multimodal analgesia, reassess, and monitor sedation with every opioid.
For cancer patients, treat any illness during the nadir as neutropenic sepsis and know the oncological emergencies.
For burns, count only partial- and full-thickness areas, start the Parkland clock at the time of the burn and titrate to urine output.
Maternity & obstetric nursing
Method
Place the woman in time: weeks of pregnancy, stage of labour or day after birth, and decide what is normal at that point.
Look for the patient in danger: the mother, the fetus or the newborn, or more than one of them.
Link the finding to its cause: VEAL CHOP for decelerations, the four Ts for bleeding, BUBBLE-HE after birth.
Choose the action that improves blood flow and oxygen first (side-lying, stopping oxytocin, fundal massage), then escalate.
Pediatric nursing
Method
Note the child’s age first: it sets the normal vital signs, the milestones and the right pain scale.
Assess airway, breathing and circulation, remembering that children compensate and then deteriorate fast.
Match the action to the development stage and involve the family.
Check that the answer is safe for a child: weight-based, no aspirin in viral illness, no codeine under 12.
Mental health nursing
Method
Decide whether there is an immediate risk: suicide, violence, a drug emergency or a physical illness.
Act on safety first: observe, remove means, de-escalate, stop a harmful drug, get help.
Choose the therapeutic response: acknowledge feelings, present reality, avoid false reassurance and “why” questions.
Respect rights: the least restrictive option, consent and confidentiality with its limits.
Nursing math & unit conversions
Metric steps
1 kg = 1000 g, 1 g = 1000 mg, 1 mg = 1000 mcg, 1 L = 1000 mL
Weight and length
1 kg = 2.2 lb, 1 lb = 16 oz, 1 in = 2.54 cm, 1 ft = 12 in
Household measures
1 tsp = 5 mL, 1 tbsp = 15 mL, 1 fl oz = 30 mL, 1 cup = 8 fl oz = 240 mL
falls 25, diagnosis 15, aid 15/30, IV 20, gait 10/20, mental status 15
NEWS2 risk
0–4 low; single 3 low–medium; 5–6 medium; ≥ 7 high
Mean arterial pressure
MAP = (SBP + 2·DBP)/3 = DBP + PP/3
Pulse pressure and shock index
PP = SBP − DBP, SI = HR/SBP
Body mass index
BMI = kg/m² = 703·lb/in²
Method
Find the score sheet that the question uses and its range (GCS 3–15, APGAR 0–10, Braden 6–23, Morse 0–125).
Score every item separately, matching the description to its level.
Add the item scores and check that the total lies inside the range.
Apply the cut-offs: for NEWS2 also look for any single parameter scoring 3.
For derived values use MAP = (SBP + 2·DBP)/3, PP = SBP − DBP, SI = HR/SBP and BMI = kg/m².
2Practice problems
1.Nursing fundamentalsMedium
A patient with a leg injury is climbing stairs with crutches. Which leg should go up first?
AThe unaffected leg
BThe crutches always go first
CBoth legs together
DThe injured leg
2.Nursing fundamentalsHard
A urine culture reports a mixed growth of several organisms. What is the most likely explanation?
AThe laboratory used the wrong test
BThe patient has several serious infections at once
CThe sample was contaminated during collection
DThe patient is resistant to all antibiotics
3.Infection control & patient safetyMedium
A family member tells the nurse, “My father is not himself. Something is wrong.” The hospital has a family-activated rapid response system. What is correct?
AThe family must wait for the next scheduled ward round to raise the concern with a doctor
BThe family should call emergency services from outside the hospital
CThe family can call the rapid response team if they are worried and staff have not responded
DOnly doctors may call the rapid response team
4.Infection control & patient safetyHard
A patient’s WBC is 4,000/mm3, with 30% neutrophils and 5% bands. What is the absolute neutrophil count (ANC)?
A3,500/mm3
B1,400/mm3
C1,200/mm3
D140/mm3
5.Prioritization & delegationMedium
A nurse asks a nursing assistant to use a mechanical lift. The assistant says they have never been trained to use it. Which right of delegation would be violated if the nurse insisted?
ARight person
BRight task
CRight supervision and evaluation
DRight directions and communication
6.Prioritization & delegationHard
A patient with diabetes takes propranolol. Which sign of hypoglycemia is most likely to still appear?
ATachycardia
BTremor
CPalpitations
DSweating
7.Clinical nursingMedium
The WHO analgesic ladder recommends:
AGiving analgesia only when pain becomes severe
BStarting all patients on strong opioids
CMoving from non-opioids to weak and then strong opioids as pain increases
DUsing only non-drug methods for cancer pain
8.Clinical nursingHard
A patient took a large paracetamol (acetaminophen) overdose six hours ago and says they feel well. Why is treatment still urgent?
AParacetamol damage only shows up in the kidneys, many weeks later
BPatients who feel well after six hours never need any treatment at all
CLiver damage develops later, and the antidote works best when given early
A patient with an upper gastrointestinal bleed has a BUN of 48 mg/dL (urea 17 mmol/L) and a normal creatinine. What is the most likely explanation?
AThe liver has stopped making urea because of the bleeding
BDigested blood adds protein, which the liver turns into urea
CSkeletal muscle is breaking down because of the blood loss
DThe kidneys have suddenly lost most of their function
10.Lab values & electrolytesHard
Which patient's result should the nurse act on first?
AHemoglobin 9.6 g/dL (96 g/L) in a patient with stable chronic kidney disease
BFerritin 15 ng/mL in a well patient with known iron-deficiency anemia on oral iron
CPlatelets 140 × 10³/µL in a patient with mild chronic liver disease
DHemoglobin 6.4 g/dL (64 g/L) with new chest pain and a pulse of 124/min
11.PharmacologyMedium
Combining an SSRI with which drug most increases the risk of serotonin syndrome?
AA monoamine oxidase inhibitor
BOmeprazole
CParacetamol
DAmoxicillin
12.PharmacologyHard
A patient who has had several courses of bleomycin develops a dry cough and worsening breathlessness. What should the nurse suspect?
AAsthma caused by anxiety
BA normal effect that will pass in a day
CHeart failure from bleomycin
DPulmonary fibrosis from bleomycin
13.Med-surg: cardiovascular & respiratoryMedium
Which investigation is most often used to confirm a pulmonary embolism?
ASputum culture
BAbdominal ultrasound
CPeak flow measurement
DCT pulmonary angiography
14.Med-surg: cardiovascular & respiratoryHard
After four days of antibiotics for pneumonia, a patient still has fever and pleuritic pain. There is dullness and reduced breath sounds at the right base. What complication should be suspected?
AA parapneumonic effusion or empyema
BAsthma triggered by the infection
CNormal recovery from pneumonia
DAn allergic reaction to the antibiotic
15.Med-surg: neuro, endocrine & renalMedium
A patient has acute glomerulonephritis with oedema and high blood pressure. Which nursing care is most appropriate?
AGive large amounts of IV fluid
BCheck the weight once a week
CMonitor BP, fluid balance and daily weight
DEncourage a high-salt diet to balance the fluids
16.Med-surg: neuro, endocrine & renalHard
An 89-year-old with stage 5 CKD and severe heart failure, who has capacity, decides not to start dialysis. What is the nurse's best response?
ARespect the decision and support symptom-focused care
BAsk the family to change the patient's mind
CStop all care, because nothing more can be done
DTell the patient they must start dialysis by law
17.Med-surg: GI, perioperative & oncologyMedium
Which area is used as a quick estimate of 1% of body surface area for small or scattered burns?
AThe examiner's palm including the fingers
BThe patient's hand and forearm
CThe patient's thumbnail
DThe patient's palm including the fingers
18.Med-surg: GI, perioperative & oncologyHard
After forearm fracture surgery, a patient has severe pain not eased by opioids, made worse by passively moving the fingers. What should the nurse do?
AReassure the patient that this pain is expected
BRaise the arm as high as possible and give a further dose of opioid
CApply ice and a tighter bandage to reduce the swelling
DLoosen any tight dressing, keep the arm at heart level and escalate
19.Maternity & obstetric nursingMedium
A woman at 37 weeks had a placental abruption. Which laboratory finding suggests she is developing disseminated intravascular coagulation (DIC)?
AA high fibrinogen level and high platelets
BA raised haemoglobin level
CA low white cell count only
DA low fibrinogen level and low platelets
20.Maternity & obstetric nursingHard
After the membranes rupture, the nurse sees the umbilical cord protruding from the vagina. What is the first action?
ACover the cord with a dry towel, keep her lying flat and wait for the doctor
BAsk the woman to push with the next contraction
CCall for help and lift the presenting part off the cord with a gloved hand
DGently push the cord back into the vagina
21.Pediatric nursingMedium
Using the 100–50–20 rule, what is the daily maintenance fluid requirement for a 15 kg child?
A1000 mL per day
B1500 mL per day
C1250 mL per day
D750 mL per day
22.Pediatric nursingHard
After hypospadias repair, a toddler has a urinary catheter. Which nursing action has priority?
ALimit fluids for the first days so that less urine passes over the repair
BKeep the catheter draining freely and check for kinks or blockage
CRemove the dressing on the first day to check the wound
DClamp the catheter for a few hours to train the bladder
23.Mental health nursingMedium
An 84-year-old asks for an over-the-counter sleep aid containing diphenhydramine. What is the main concern?
AIts anticholinergic effects can cause confusion, urine retention and falls
BIt has no effects at all in people over 80, so it will not help her sleep
CIt raises blood pressure to dangerous levels in older adults
DIt is a strong opioid that causes severe dependence
24.Mental health nursingHard
A patient says, "My boss didn't say hello this morning, so she must think I'm useless." Which cognitive distortion is shown, and what is a helpful nursing response?
AMind reading; ask what other reasons there might be for the boss's behaviour
BPersonalisation; advise the patient to ask for a new manager
CAll-or-nothing thinking; agree that the boss is being unfair
DCatastrophising; tell the patient that she will definitely not be fired
25.Nursing math & unit conversionsMedium
Practice exercise (made-up values, not clinical guidance). A dose is charted at 10:30 AM. Which entry is the same time on the 24-hour clock? Click it.
10:30 AM
122:30
211:30
309:30
410:30
26.Nursing math & unit conversionsHard
Practice exercise (made-up values, not clinical guidance). An infusion starts at 20:25 and finishes at 01:05 the next morning (24-hour clock). How many hours t did it run? Give the answer in hours as a decimal, rounded to two decimal places.
20:2501:05
t = h
27.Dosage calculationsMedium
A child weighing 8 kg is prescribed 10 mg/kg of a drug. The stock solution contains 25 mg/mL. Draw up the dose: what volume V do you give?
8 kg10 mg/kg25 mg/mL
V = mL
28.Dosage calculationsHard
A patient is 188 cm tall and weighs 57 kg. The prescription is 100 mg/m². Using the Mosteller formula BSA = √(height (cm) × weight (kg)/3600), find the dose D in mg.
188 cm57 kg100 mg/m²
D = mg
29.IV infusion ratesMedium
An infusion is ordered at 100 mL/h, but no pump is available. It runs by gravity through a giving set of 60 gtt/mL. Find the drip rate R in drops per minute.
100 mL/h60 gtt/mL
R = gtt/min
30.IV infusion ratesHard
An infusion of 100 mg in 250 mL runs at 12 mL/h. How many micrograms per minute D does the patient receive?
100 mg/250 mL12 mL/h
D = mcg/min
31.IV fluids & fluid balanceMedium
Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The patient weighs 68 kg. Find the average urine output U in mL/kg/h. Round to two decimal places.
Practice exercise (made-up values, not clinical guidance). A 1000 mL bag was started at 12:45 and runs by pump at 150 mL/h. How many mL V are left in the bag at 17:15?
1000 mL150 mL/h12:45 → 17:15
V = mL
33.Clinical assessment scoresMedium
Practice exercise (made-up values, not clinical guidance). Use the NEWS2 chart (SpO₂ scale 1) for these observations: respiration rate 23/min, SpO₂ 91% on supplemental oxygen, blood pressure 78/46 mmHg, pulse 88/min, alert, temperature 37.9 °C. What is the NEWS2 total score?
RR 23SpO₂ 91%O₂SBP 78HR 88AT 37.9 °C
NEWS2 =
34.Clinical assessment scoresHard
Practice exercise (made-up values, not clinical guidance). The team aims for a mean arterial pressure of at least 60 mmHg. A patient’s systolic pressure is 92 mmHg. Using MAP = (SBP + 2·DBP)/3, what is the lowest diastolic pressure DBP that still gives a MAP of 60 mmHg?
MAP 60 mmHgSBP 92 mmHg
DBP = mmHg
3Solutions
1.Nursing fundamentals
Answer: A · The unaffected leg
Why this is the answer
Going up, the strong leg steps first and lifts the body, followed by the crutches and the injured leg. Going down, the crutches and injured leg go first.
Answer
A · The unaffected leg
2.Nursing fundamentals
Answer: C · The sample was contaminated during collection
Why this is the answer
A mixed growth usually means skin or perineal bacteria contaminated the sample. A clean-catch midstream sample, or a sample from the catheter sampling port, gives a more reliable result.
Answer
C · The sample was contaminated during collection
3.Infection control & patient safety
Answer: C · The family can call the rapid response team if they are worried and staff have not responded
Why this is the answer
Family-activated rapid response systems allow patients and families to call for help directly when they notice a worrying change. The nurse should also take the concern seriously and assess the patient.
Answer
C · The family can call the rapid response team if they are worried and staff have not responded
4.Infection control & patient safety
Answer: B · 1,400/mm3
Why this is the answer
ANC = 4,000 × (0.30 + 0.05) = 1,400/mm3. This is below normal (neutropenia), so the patient has a raised risk of infection.
Answer
B · 1,400/mm3
5.Prioritization & delegation
Answer: A · Right person
Why this is the answer
Right person means the delegate has the training and competence for the task. Using a lift is normally a delegable task, but not to someone who has not been trained. The nurse should arrange training or do the task with help.
Answer
A · Right person
6.Prioritization & delegation
Answer: D · Sweating
Why this is the answer
Beta-blockers can hide tachycardia, palpitations and tremor during hypoglycemia. Sweating is mainly cholinergic, so it usually remains, and patients are taught to check glucose when they sweat.
Answer
D · Sweating
7.Clinical nursing
Answer: C · Moving from non-opioids to weak and then strong opioids as pain increases
Why this is the answer
The ladder moves from non-opioids (such as paracetamol) to weak opioids and then strong opioids, with adjuvants at any step. Regular dosing is preferred for persistent pain.
Answer
C · Moving from non-opioids to weak and then strong opioids as pain increases
8.Clinical nursing
Answer: C · Liver damage develops later, and the antidote works best when given early
Why this is the answer
Paracetamol overdose may cause few early symptoms, but liver failure can develop over days. Acetylcysteine is most effective when started early, guided by timed paracetamol levels.
Answer
C · Liver damage develops later, and the antidote works best when given early
9.Lab values & electrolytes
Answer: B · Digested blood adds protein, which the liver turns into urea
Why this is the answer
Blood in the upper gut is digested, and the absorbed protein is converted to urea, so the BUN rises out of proportion to the creatinine. Reduced kidney blood flow from volume loss can add to the rise.Checked against:BUN - blood test · MedlinePlus (NIH) (2025)
Answer
B · Digested blood adds protein, which the liver turns into urea
10.Lab values & electrolytes
Answer: D · Hemoglobin 6.4 g/dL (64 g/L) with new chest pain and a pulse of 124/min
Why this is the answer
Severe anemia with chest pain and tachycardia suggests the heart is not receiving enough oxygen, which needs urgent action, often including transfusion. The other results are mildly abnormal but expected or stable.Checked against:Anemia · StatPearls (NCBI Bookshelf) (2026)
Answer
D · Hemoglobin 6.4 g/dL (64 g/L) with new chest pain and a pulse of 124/min
11.Pharmacology
Answer: A · A monoamine oxidase inhibitor
Why this is the answer
SSRIs block serotonin reuptake and MAO inhibitors block its breakdown. Together they can cause serotonin syndrome with agitation, hyperthermia, tremor and clonus.
Answer
A · A monoamine oxidase inhibitor
12.Pharmacology
Answer: D · Pulmonary fibrosis from bleomycin
Why this is the answer
Bleomycin can cause pneumonitis and pulmonary fibrosis, especially at higher cumulative doses. New respiratory symptoms are reported, and lung function may be monitored.
Answer
D · Pulmonary fibrosis from bleomycin
13.Med-surg: cardiovascular & respiratory
Answer: D · CT pulmonary angiography
Why this is the answer
CT pulmonary angiography (CTPA) shows filling defects in the pulmonary arteries. It uses iodinated contrast, so renal function and contrast allergy are checked. A ventilation–perfusion (V/Q) scan is an alternative, for example in pregnancy or renal impairment.
Answer
D · CT pulmonary angiography
14.Med-surg: cardiovascular & respiratory
Answer: A · A parapneumonic effusion or empyema
Why this is the answer
Persistent fever and signs of pleural fluid suggest a parapneumonic effusion, which may become infected (empyema). Ultrasound and diagnostic pleural aspiration are needed, and an infected collection usually needs a chest drain in addition to antibiotics.
Answer
A · A parapneumonic effusion or empyema
15.Med-surg: neuro, endocrine & renal
Answer: C · Monitor BP, fluid balance and daily weight
Why this is the answer
In acute glomerulonephritis, salt and water retention cause oedema and hypertension. Close monitoring of BP, input and output and daily weights is needed, often with salt and fluid restriction and antihypertensives.
Answer
C · Monitor BP, fluid balance and daily weight
16.Med-surg: neuro, endocrine & renal
Answer: A · Respect the decision and support symptom-focused care
Why this is the answer
A competent patient can refuse dialysis. The nurse makes sure the choice is informed, respects it and supports conservative kidney management, with symptom control, advance care planning and palliative care input.
Answer
A · Respect the decision and support symptom-focused care
17.Med-surg: GI, perioperative & oncology
Answer: D · The patient's palm including the fingers
Why this is the answer
The patient's palm with the fingers together is about 1% of their total body surface area. It is useful for small or patchy burns. Simple erythema (superficial burns) is not included in the total.
Answer
D · The patient's palm including the fingers
18.Med-surg: GI, perioperative & oncology
Answer: D · Loosen any tight dressing, keep the arm at heart level and escalate
Why this is the answer
These are early signs of compartment syndrome, where raised pressure in a muscle compartment reduces blood flow. Constrictive dressings are released, the limb is kept at heart level and urgent surgical review is needed, as fasciotomy may be required.
Answer
D · Loosen any tight dressing, keep the arm at heart level and escalate
19.Maternity & obstetric nursing
Answer: D · A low fibrinogen level and low platelets
Why this is the answer
In DIC, widespread clotting consumes fibrinogen and platelets, leading to bleeding. Fibrinogen is normally raised in pregnancy, so a low level is especially concerning.
Answer
D · A low fibrinogen level and low platelets
20.Maternity & obstetric nursing
Answer: C · Call for help and lift the presenting part off the cord with a gloved hand
Why this is the answer
Relieve the pressure on the cord by keeping the presenting part off it, call for urgent help and use a knee–chest or head-down position. Do not try to replace the cord; if it is outside, it can be covered with warm, moist saline gauze. Birth is usually expedited.
Answer
C · Call for help and lift the presenting part off the cord with a gloved hand
21.Pediatric nursing
Answer: C · 1250 mL per day
Why this is the answer
First 10 kg: 10 × 100 = 1000 mL. Next 5 kg: 5 × 50 = 250 mL. Total = 1250 mL per day, or about 52 mL per hour.
Answer
C · 1250 mL per day
22.Pediatric nursing
Answer: B · Keep the catheter draining freely and check for kinks or blockage
Why this is the answer
After repair, the catheter or stent protects the new urethra while it heals. It must drain freely; blockage causes bladder spasm and pressure on the repair. Fluids are encouraged, and the dressing is managed as the surgeon directs.
Answer
B · Keep the catheter draining freely and check for kinks or blockage
23.Mental health nursing
Answer: A · Its anticholinergic effects can cause confusion, urine retention and falls
Why this is the answer
Diphenhydramine is strongly anticholinergic and sedating. In older adults, it can cause delirium, constipation, urinary retention and falls, and is generally avoided.
Answer
A · Its anticholinergic effects can cause confusion, urine retention and falls
24.Mental health nursing
Answer: A · Mind reading; ask what other reasons there might be for the boss's behaviour
Why this is the answer
Mind reading is assuming others' thoughts without evidence. Exploring alternative explanations, such as the boss being busy, helps the patient test the thought and reduce distress.
Answer
A · Mind reading; ask what other reasons there might be for the boss's behaviour
25.Nursing math & unit conversions
Answer: 10:30
24-hour clock: from 1 PM onwards add 12 to the hour (3:45 PM = 15:45). Midnight to 12:59 AM is 00:00–00:59, and 12:00–12:59 PM stays 12:00–12:59. Going back, subtract 12 from hours 13–23 and add PM; hours 00 become 12 AM. Count time across midnight in two parts: up to 24:00 (00:00), then from 00:00 on.
Convert the hour
10 AM → 10
Answer
10:30
Answer
10:30
26.Nursing math & unit conversions
Answer: t = 4.67 h
24-hour clock: from 1 PM onwards add 12 to the hour (3:45 PM = 15:45). Midnight to 12:59 AM is 00:00–00:59, and 12:00–12:59 PM stays 12:00–12:59. Going back, subtract 12 from hours 13–23 and add PM; hours 00 become 12 AM. Count time across midnight in two parts: up to 24:00 (00:00), then from 00:00 on.
Before midnight
20:25 → 24:00 = 215 min
After midnight
00:00 → 01:05 = 65 min
Total
215 + 65 = 280 min
t = 280/60 = 4.667 ≈ 4.67 h
Answer
t = 4.67 h
27.Dosage calculations
Answer: V = 3.2 mL
Drawing up a dose: volume = (prescribed dose/stock strength) × stock volume. Convert to the same units first, then check that the volume fits the syringe and lands on one of its graduations.
Dose from body weight
D = 10·8 = 80 mg
Volume
V = 80/25 = 3.2 mL
On the syringe
On this 10 mL syringe every small line is 0.2 mL.
Answer
V = 3.2 mL
28.Dosage calculations
Answer: D = 172.5 mg
Body-surface-area dosing: many cytotoxic and some paediatric doses are prescribed per square metre of body surface area: dose (mg) = dose per m² × BSA (m²). The Mosteller formula estimates BSA = √(height (cm) × weight (kg)/3600).
Body surface area
BSA = √(188·57/3600) = √2.977 = 1.725 m²
Dose
D = 100·1.725 = 172.5 mg
Answer
D = 172.5 mg
29.IV infusion rates
Answer: R = 100 gtt/min
Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.
Millilitres per minute
100/60 = 1.667 mL/min
Drip rate
R = 1.667·60 = 100 gtt/min
Answer
R = 100 gtt/min
With a microdrip set (60 gtt/mL), gtt/min equals mL/h.
30.IV infusion rates
Answer: D = 80 mcg/min
Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).
Concentration
100000 mcg/250 mL = 400 mcg/mL
Dose per hour
12·400 = 4800 mcg/h
Dose per minute
D = 4800/60 = 80 mcg/min
Answer
D = 80 mcg/min
31.IV fluids & fluid balance
Answer: U = 1.32 mL/kg/h
Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.
Total urine
225 + 475 + 375 = 1075 mL
Per kilogram per hour
U = 1075/(68·12) = 1.317 ≈ 1.32 mL/kg/h
Answer
U = 1.32 mL/kg/h
32.IV fluids & fluid balance
Answer: V = 325 mL
Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.
Elapsed time
12:45 → 17:15 = 4.5 h
Volume infused
150·4.5 = 675 mL
Volume left
V = 1000 − 675 = 325 mL
Answer
V = 325 mL
33.Clinical assessment scores
Answer: NEWS2 = 10
NEWS2 (National Early Warning Score 2, Royal College of Physicians 2017): score each of the seven parameters with the chart (respiration rate, SpO₂ on scale 1, air or supplemental oxygen, systolic blood pressure, pulse, consciousness on the ACVPU scale and temperature) and add the scores. Clinical risk: 0–4 low; a score of 3 in any single parameter low–medium; 5–6 medium; 7 or more high. A total of 5 or more needs an urgent response.
Score each parameter
RR 23/min → 2
SpO₂ 91% → 3
on oxygen → 2
SBP 78 mmHg → 3
HR 88/min → 0
alert (A) → 0
T 37.9 °C → 0
Add
NEWS2 = 2 + 3 + 2 + 3 + 0 + 0 + 0 = 10
Answer
NEWS2 = 10
34.Clinical assessment scores
Answer: DBP = 44 mmHg
Blood pressure values: pulse pressure PP = SBP − DBP. Mean arterial pressure MAP ≈ (SBP + 2·DBP)/3 = DBP + PP/3, an estimate based on the heart spending about two thirds of each beat in diastole at a normal heart rate (less accurate when the heart rate is fast); a MAP of at least about 65 mmHg is a common target for organ perfusion. The shock index SI = heart rate/SBP is normally about 0.5–0.7; a value above about 1 is a warning sign of shock.
Rearrange
DBP = (3·MAP − SBP)/2
Substitute
DBP = (3·60 − 92)/2 = 88/2 = 44 mmHg
Answer
DBP = 44 mmHg
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