Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
Infection control & patient safety
Method
Start with standard precautions for every patient: hand hygiene, PPE for the expected exposure, safe sharps.
Keep sterile items sterile: if in doubt, it is not sterile; replace, never wipe.
Prevent harm in the environment: fall measures, restraints only as a last resort, RACE and PASS for fire.
Check the rights of medication administration, two identifiers and extra safeguards for high-alert drugs; report errors and near misses.
Lab values & electrolytes
Method
Compare the value with the laboratory’s own reference range, then with the patient’s baseline and trend.
Check the sample: hemolysis, a delay, or blood drawn near an IV can give false results.
Link the value to its typical signs and to the drugs and conditions that cause it.
Look for interactions: low potassium or magnesium increases digoxin toxicity; dehydration raises lithium.
Act on the patient: assess, hold a drug if the level is unsafe, read back critical values and inform the prescriber.
2Practice problems
1.Nursing fundamentalsMedium
A patient with right-sided weakness is moving from bed to chair. Where should the chair be placed?
AOn the patient's right side, close to the bed
BAcross the room so the patient can practise walking
COn the patient's left side, close to the bed
DAt the foot of the bed facing away
2.Nursing fundamentalsHard
A urine culture reports a mixed growth of several organisms. What is the most likely explanation?
AThe patient is resistant to all antibiotics
BThe patient has several serious infections at once
CThe laboratory used the wrong test
DThe sample was contaminated during collection
3.Clinical nursingMedium
In suspected sepsis, what should ideally be collected before the first dose of antibiotics, as long as it does not delay treatment?
AA fasting cholesterol level
BBlood cultures
CA stool sample for occult blood
DA 24-hour urine collection
4.Clinical nursingHard
During a blood transfusion, an older patient with heart failure becomes breathless with a rising blood pressure, raised JVP and crackles in the lungs. What is the most likely cause?
ATransfusion-related acute lung injury with hypotension
BAnaphylaxis
CA febrile non-haemolytic reaction
DTransfusion-associated circulatory overload
5.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.25, PaCO₂ 57 mmHg (7.6 kPa) and HCO₃⁻ 24 mmol/L. The primary disorder is respiratory acidosis. How far is it compensated? Click your answer.
pH 7.25PaCO₂ 57 mmHg (7.6 kPa)HCO₃⁻ 24 mmol/L
1uncompensated
2partially compensated
3fully compensated
6.Arterial blood gas interpretationHard
A practice gas shows pH 7.28, PaCO₂ 24 mmHg (3.2 kPa) and HCO₃⁻ 11 mmol/L, with Na⁺ 139 and Cl⁻ 99 mmol/L. Use the anion gap and the delta ratio to click the best interpretation.
Practice exercise (made-up values, not clinical guidance). A practice patient is assessed with the Braden scale: sensory perception: no impairment; moisture: very moist; activity: walks frequently; mobility: no limitation; nutrition: adequate; friction and shear: no apparent problem. Find the Braden total B.
6–23
B =
8.Clinical assessment scoresHard
Practice exercise (made-up values, not clinical guidance). A practice patient is assessed with the Braden scale: sensory perception: slightly limited; moisture: very moist; activity: walks frequently; mobility: no limitation; nutrition: excellent; friction and shear: no apparent problem. Use the bands 19–23 not at risk, 15–18 mild, 13–14 moderate, 10–12 high and 9 or below very high. Click the risk level.
Practice exercise (made-up values, not clinical guidance). A 54 kg patient needs 1.5 g of protein per kg a day. The tube feed contains 55 g of protein per litre and runs at 40 mL/h for 20 hours a day. A protein powder supplies 6 g of protein per scoop. How many scoops n a day are needed to cover the shortfall? Round up to a whole scoop.
Practice exercise (made-up values, not clinical guidance). Over 24 hours a patient receives 1200 mL of parenteral nutrition with final concentrations of 20% dextrose and 4% amino acids, plus 500 mL of 10% lipid emulsion (1.1 kcal/mL). Find the non-protein energy NPC in kcal per day. Round to the nearest whole number.
1200 mLdextrose 20%amino acids 4%lipid 500 mL · 1.1 kcal/mL
NPC = kcal/day
11.ECG rhythm strip interpretationMedium
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Bazett’s formula QTc = QT/√RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
12.ECG rhythm strip interpretationHard
This patient has a pacemaker. Interpret the lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1paced rhythm, failure to capture
2idioventricular rhythm
3dual-chamber (AV) paced rhythm
4second-degree AV block type II
13.Prioritization & delegationMedium
A malnourished patient admitted with alcohol use disorder needs IV glucose. Which vitamin is given before or with it?
AThiamine (vitamin B1)
BVitamin C (ascorbic acid)
CVitamin K (phytonadione)
DVitamin D (calciferol)
14.Prioritization & delegationHard
A patient is admitted with inhalational anthrax. Which precautions are needed?
AAirborne precautions in a negative-pressure room for the whole of the hospital stay
BFull contact and droplet precautions for all staff and visitors on the unit
CDroplet precautions with a surgical mask for everyone who enters
DStandard precautions, because it does not usually spread from person to person
15.Infection control & patient safetyMedium
In a hospital fire, which means of moving patients is usually avoided?
AElevators (lifts)
BWheeling beds through fire doors
CStairs
DMoving horizontally to another area on the same floor behind fire doors
16.Infection control & patient safetyHard
A chemical cloud has been released near the hospital, and authorities order “shelter in place”. What should staff do?
AKeep everyone inside, close windows and doors and shut off outside air intake
BOpen the windows to let fresh air into the wards and dilute the chemical
CSend all visitors home through the main entrance
DEvacuate all patients into the car park at once
17.Lab values & electrolytesMedium
A patient had a total thyroidectomy yesterday. Which laboratory value is most important to monitor in the first days after surgery?
ASerum glucose
BSerum calcium
CSerum sodium
DSerum potassium
18.Lab values & electrolytesHard
At the start of a shift, the nurse reviews four new results. Which patient needs attention first?
APotassium 5.2 mEq/L in a patient with stable chronic kidney disease
BSodium 119 mEq/L in a patient with new confusion and vomiting
CHemoglobin 11.0 g/dL (110 g/L) in a patient with rheumatoid arthritis
DGlucose 180 mg/dL (10 mmol/L) after a meal in a patient with diabetes
3Solutions
1.Nursing fundamentals
Answer: C · On the patient's left side, close to the bed
Why this is the answer
Placing the chair on the strong side lets the patient pivot and bear weight on the stronger leg, making the transfer safer.
Answer
C · On the patient's left side, close to the bed
2.Nursing fundamentals
Answer: D · The sample was contaminated during collection
Why this is the answer
A mixed growth usually means skin or perineal bacteria contaminated the sample. A clean-catch midstream sample, or a sample from the catheter sampling port, gives a more reliable result.
Answer
D · The sample was contaminated during collection
3.Clinical nursing
Answer: B · Blood cultures
Why this is the answer
Blood cultures taken before antibiotics are more likely to grow the organism, which allows targeted treatment later. Antibiotics should still be given promptly and must not be delayed.
Answer
B · Blood cultures
4.Clinical nursing
Answer: D · Transfusion-associated circulatory overload
Why this is the answer
TACO causes pulmonary oedema with hypertension and raised venous pressure, especially in older people and those with heart or kidney disease. TRALI usually presents with hypotension and no fluid overload signs.
Answer
D · Transfusion-associated circulatory overload
5.Arterial blood gas interpretation
Answer: uncompensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.25: acidaemia (below 7.35)
PaCO₂ 57 mmHg: high (35–45)
HCO₃⁻ 24 mmol/L: normal (22–26)
Compensation
uncompensated
Answer
uncompensated
6.Arterial blood gas interpretation
Answer: pure high-gap acidosis
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 139 − (99 + 11) = 29
Delta ratio
(29 − 12)/(24 − 11) = 1.308
pure high-gap acidosis
Answer
pure high-gap acidosis
7.Clinical assessment scores
Answer: B = 20
Braden scale: six subscales for pressure-injury risk. Sensory perception, moisture, activity, mobility and nutrition score 1 to 4, from the worst level (1) to no problem (4); friction and shear scores 1 to 3. The total runs from 6 to 23, and a lower total means a higher risk. Common bands: 19–23 not at risk, 15–18 mild risk, 13–14 moderate risk, 10–12 high risk and 9 or below very high risk.
Score each subscale
sensory perception: no impairment → 4
moisture: very moist → 2
activity: walks frequently → 4
mobility: no limitation → 4
nutrition: adequate → 3
friction and shear: no apparent problem → 3
Add
Braden total = 4 + 2 + 4 + 4 + 3 + 3 = 20
Answer
B = 20
8.Clinical assessment scores
Answer: not at risk
Braden scale: six subscales for pressure-injury risk. Sensory perception, moisture, activity, mobility and nutrition score 1 to 4, from the worst level (1) to no problem (4); friction and shear scores 1 to 3. The total runs from 6 to 23, and a lower total means a higher risk. Common bands: 19–23 not at risk, 15–18 mild risk, 13–14 moderate risk, 10–12 high risk and 9 or below very high risk.
Score each subscale
sensory perception: slightly limited → 3
moisture: very moist → 2
activity: walks frequently → 4
mobility: no limitation → 4
nutrition: excellent → 4
friction and shear: no apparent problem → 3
Add
Braden total = 3 + 2 + 4 + 4 + 4 + 3 = 20
Risk level
20 → not at risk
Answer
not at risk
9.Enteral & parenteral nutrition calculations
Answer: n = 7
Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.
Protein needed
1.5·54 = 81 g/day
Protein from the feed
40·20 = 800 mL = 0.8 L
0.8·55 = 44 g/day
Shortfall
ΔP = 81 − 44 = 37 g
Scoops
37/6 = 6.167 → n = 7
Answer
n = 7
10.Enteral & parenteral nutrition calculations
Answer: NPC = 1366 kcal/day
Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.
Grams of dextrose and amino acids
dextrose: 20·1200/100 = 240 g
amino acids: 4·1200/100 = 48 g
Kilocalories per component
dextrose: 240·3.4 = 816 kcal
amino acids: 48·4 = 192 kcal
lipid: 500·1.1 = 550 kcal
Non-protein energy
NPC = 816 + 550 = 1366 kcal/day
Answer
NPC = 1366 kcal/day
11.ECG rhythm strip interpretation
Answer: QTc = 0.482 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 10.5 × 0.04 = 0.42 s
RR = 19 × 0.04 = 0.76 s
Bazett’s formula
QTc = 0.42/√0.76 = 0.42/0.8718 = 0.482 s
Answer
QTc = 0.482 s
Above the usual limits for both men (about 0.45 s) and women (about 0.46 s): prolonged. (482 ms)
12.ECG rhythm strip interpretation
Answer: paced rhythm, failure to capture
Paced rhythms: a pacemaker impulse shows as a narrow vertical pacing spike. After a ventricular spike the QRS is wide (0.12 s or more), because the impulse spreads from the lead through the muscle instead of the conduction system; with right-ventricular pacing it is often mostly negative in lead II. A spike before each P wave means atrial pacing, and a dual-chamber (AV) pacemaker shows an atrial spike and a P wave, then, after the programmed AV delay, a ventricular spike and a wide QRS. Capture means every spike is followed by a depolarisation. Failure to capture is a spike without a P wave or QRS after it; failure to sense (spikes that ignore the patient’s own beats) and failure to pace (no spike when one is due) are the other classic malfunctions.
Five steps
1. Rate: 5 QRS complexes in 6 s, × 10 = 50 per minute.
2. Rhythm: the pacing spikes are regular (every 0.96 s), but the R–R is not, because a QRS is missing after some spikes.
3. P waves: none visible.
4. PR interval: not measurable.
5. QRS: 0.16 s and wide after the captured spikes; one spike is not followed by a QRS (no capture).
Interpretation
paced rhythm, failure to capture
Answer
paced rhythm, failure to capture
Failure to capture: the pacemaker fires but the heart does not respond. Textbooks treat it as urgent to report, because the patient may depend on the pacemaker.
13.Prioritization & delegation
Answer: A · Thiamine (vitamin B1)
Why this is the answer
Thiamine deficiency is common in heavy alcohol use, and giving glucose without thiamine can trigger Wernicke encephalopathy. Thiamine is given before or with glucose.
Answer
A · Thiamine (vitamin B1)
14.Prioritization & delegation
Answer: D · Standard precautions, because it does not usually spread from person to person
Why this is the answer
Inhalational anthrax is not spread from person to person, so standard precautions are used. Contact precautions may be added for skin (cutaneous) anthrax with draining lesions.
Answer
D · Standard precautions, because it does not usually spread from person to person
15.Infection control & patient safety
Answer: A · Elevators (lifts)
Why this is the answer
Elevators are not used during a fire unless the fire service directs it, because they can stop or fill with smoke. Patients are usually moved horizontally behind fire doors first, then downstairs if needed.
Answer
A · Elevators (lifts)
16.Infection control & patient safety
Answer: A · Keep everyone inside, close windows and doors and shut off outside air intake
Why this is the answer
Sheltering in place keeps people inside, away from the hazard. Windows and doors are closed and ventilation systems that bring in outside air are shut off until the all-clear.
Answer
A · Keep everyone inside, close windows and doors and shut off outside air intake
17.Lab values & electrolytes
Answer: B · Serum calcium
Why this is the answer
The parathyroid glands can be injured or removed during thyroidectomy, so parathyroid hormone falls and hypocalcemia can follow. The nurse monitors calcium and checks for tingling around the mouth, muscle cramps and Chvostek or Trousseau signs.Checked against:Hypoparathyroidism · MedlinePlus (NIH) (2026)
Answer
B · Serum calcium
18.Lab values & electrolytes
Answer: B · Sodium 119 mEq/L in a patient with new confusion and vomiting
Why this is the answer
Severe hyponatremia with confusion and vomiting suggests cerebral edema and can progress to seizures and coma. The other results are mildly abnormal and expected for those conditions, so they are less urgent.Checked against:Low blood sodium - Medical Encyclopedia · MedlinePlus (NIH) (2025); Sodium Blood Test · MedlinePlus (NIH) (2024)
Answer
B · Sodium 119 mEq/L in a patient with new confusion and vomiting