Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
Infection control & patient safety
Method
Start with standard precautions for every patient: hand hygiene, PPE for the expected exposure, safe sharps.
Keep sterile items sterile: if in doubt, it is not sterile; replace, never wipe.
Prevent harm in the environment: fall measures, restraints only as a last resort, RACE and PASS for fire.
Check the rights of medication administration, two identifiers and extra safeguards for high-alert drugs; report errors and near misses.
Lab values & electrolytes
Method
Compare the value with the laboratory’s own reference range, then with the patient’s baseline and trend.
Check the sample: hemolysis, a delay, or blood drawn near an IV can give false results.
Link the value to its typical signs and to the drugs and conditions that cause it.
Look for interactions: low potassium or magnesium increases digoxin toxicity; dehydration raises lithium.
Act on the patient: assess, hold a drug if the level is unsafe, read back critical values and inform the prescriber.
2Practice problems
1.Nursing fundamentalsMedium
Why should a tourniquet not be left on for a long time before taking blood?
AIt can change the results, for example by concentrating the blood
BIt makes the blood turn blue in the tube
CIt stops the needle from entering the vein because the vein is too hard
DIt makes the patient's arm grow stronger
2.Nursing fundamentalsHard
An AED is about to deliver a shock. What must the rescuer do?
ARemove the pads and place them again
BHold the patient's hand to reassure them
CMake sure no one is touching the patient
DKeep doing chest compressions during the shock
3.Clinical nursingMedium
When giving insulin, which statement is correct?
AInsulin should be shaken hard before use
BAlways inject into the same spot for consistent absorption
CRapid-acting insulin is given only at bedtime
DRotate injection sites to avoid lipohypertrophy
4.Clinical nursingHard
A patient with a central venous catheter needs the line removed. Which position reduces the risk of air embolism during removal of a neck or chest line?
ALying on the right side with the legs raised
BLying flat or slightly head-down, holding the breath or breathing out
CSitting fully upright and taking a deep breath in as the line comes out
DStanding up and walking
5.Arterial blood gas interpretationMedium
A practice gas shows PaCO₂ 55 mmHg (7.3 kPa). Use the rule that in acute respiratory acidosis HCO₃⁻ rises by 1 mmol/L for every 10 mmHg that PaCO₂ is above 40, starting from HCO₃⁻ 24 mmol/L, to find the expected HCO₃⁻.
A practice gas shows a metabolic alkalosis with HCO₃⁻ 35 mmol/L. Use expected PaCO₂ = 0.7·HCO₃⁻ + 21 to find the expected PaCO₂.
HCO₃⁻ 35 mmol/L
PaCO₂ = mmHg
7.Clinical assessment scoresMedium
Practice exercise (made-up values, not clinical guidance). A practice chart records GCS 10, with E3 and V3. What motor score M was recorded, and which response does it describe? Give the number.
GCS 10E3V3
M =
8.Clinical assessment scoresHard
Practice exercise (made-up values, not clinical guidance). An adult weighs 78 kg and is 170 cm tall. Calculate the BMI and click the WHO weight category.
Practice exercise (made-up values, not clinical guidance). A woman is 162 cm tall and weighs 78 kg. Find the actual weight as a percentage of the ideal body weight, %IBW, using the Devine formula (1 in = 2.54 cm). Round to the nearest whole number.
Practice exercise (made-up values, not clinical guidance). A 59 kg adult receives 1500 mL of parenteral nutrition containing 10% dextrose, infused over 12 hours. Find the glucose infusion rate GIR in mg/kg/min. Round to two decimal places.
59 kg1500 mLdextrose 10%12 h
GIR = mg/kg/min
11.ECG rhythm strip interpretationMedium
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Fridericia’s formula QTc = QT/∛RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
12.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1third-degree (complete) AV block
2junctional rhythm
3sinus bradycardia
4asystole
13.Prioritization & delegationMedium
A patient has a sudden nosebleed, is alert and is breathing normally. What does the nurse do first?
ATilt the head back and apply ice to the back of the neck
BSit the patient up, lean them forward and pinch the soft part of the nose
CAsk the patient to blow the nose hard to clear the clots
DLie the patient flat on their back with a pillow under the knees
14.Prioritization & delegationHard
Which patient finding after a total knee replacement needs the nurse’s action first?
ASudden calf pain and swelling in the operated leg, with new breathlessness
BPain of 4/10 when the physiotherapist bends the knee during the morning session
CAsks for an ice pack to help with swelling around the knee
DA small amount of dried blood on the dressing
15.Infection control & patient safetyMedium
An older adult has trouble getting in and out of the bath. Which measures make bathing safer?
AA loose rug beside the tub to stand on
BBath oil to help the person slide in and out
CLocking the bathroom door for privacy
DA shower chair, grab bars and a non-slip mat
16.Infection control & patient safetyHard
A confused patient keeps pulling at a nasogastric tube. Which approach should be tried first?
ALess restrictive measures, such as reorientation and a sitter
BRemoving the tube without consulting the team
CWrist restraints straight away to protect the tube
DA sedative so that the patient sleeps quietly through the night
17.Lab values & electrolytesMedium
When should the nurse check the glucose before giving a mealtime dose of rapid-acting insulin (such as lispro)?
AOnly once a day, then giving the same dose before every meal
BJust before the meal, giving insulin when the food is ready
CAt bedtime only, then giving the mealtime insulin overnight
DTwo hours after the meal, then giving the insulin dose
18.Lab values & electrolytesHard
A patient on a stable dose of levothyroxine now has a TSH of 9.8 mIU/L. She recently started taking her calcium and iron supplements with her morning levothyroxine. What is the most likely explanation?
AThe supplements are reducing levothyroxine absorption
BThe TSH is low, showing that the dose is now too high
CThe supplements are causing an overactive thyroid gland
DThe result is normal for a person on levothyroxine therapy
3Solutions
1.Nursing fundamentals
Answer: A · It can change the results, for example by concentrating the blood
Why this is the answer
Prolonged tourniquet time causes fluid to leave the vessel and can alter results such as potassium and protein. It is applied only as long as needed.
Answer
A · It can change the results, for example by concentrating the blood
2.Nursing fundamentals
Answer: C · Make sure no one is touching the patient
Why this is the answer
Before the shock the rescuer shouts a warning and checks that everyone is clear. Compressions restart straight after the shock as the AED instructs.
Answer
C · Make sure no one is touching the patient
3.Clinical nursing
Answer: D · Rotate injection sites to avoid lipohypertrophy
Why this is the answer
Rotating sites prevents fatty lumps that make absorption unpredictable. Cloudy insulins are mixed by gentle rolling, not shaking.
Answer
D · Rotate injection sites to avoid lipohypertrophy
4.Clinical nursing
Answer: B · Lying flat or slightly head-down, holding the breath or breathing out
Why this is the answer
A flat or head-down position and a Valsalva manoeuvre or breath-hold raise central venous pressure, reducing the risk of air being drawn in. An occlusive dressing is then applied.
Answer
B · Lying flat or slightly head-down, holding the breath or breathing out
5.Arterial blood gas interpretation
Answer: HCO₃⁻ = 25.5 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Change in PaCO₂
|55 − 40| = 15 mmHg → 1.5 × 10 mmHg
Expected HCO₃⁻
HCO₃⁻ = 24 + 1·1.5 = 25.5 mmol/L
Answer
HCO₃⁻ = 25.5 mmol/L
6.Arterial blood gas interpretation
Answer: PaCO₂ = 45.5 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
0.7·35 + 21 = 45.5 mmHg
Answer
PaCO₂ = 45.5 mmHg
The rise has a limit: PaCO₂ rarely goes above about 55 mmHg from compensation alone.
7.Clinical assessment scores
Answer: M = 4
Glasgow Coma Scale: add the best response in three areas. Eye opening E: 4 spontaneous, 3 to sound or speech, 2 to pressure, 1 none. Verbal V: 5 oriented, 4 confused, 3 inappropriate words, 2 incomprehensible sounds, 1 none. Motor M: 6 obeys commands, 5 localises, 4 normal flexion (withdraws), 3 abnormal flexion, 2 extension, 1 none. The total runs from 3 to 15. After a head injury, 13–15 is usually called mild, 9–12 moderate and 3–8 severe.
Motor score
M = 10 − 3 − 3 = 4
M4: withdraws the limb from pressure (normal flexion)
Answer
M = 4
8.Clinical assessment scores
Answer: overweight
Body mass index: BMI = weight (kg)/height (m)², with the height converted to metres first. With pounds and inches, BMI = 703 × weight (lb)/height (in)². WHO adult categories: below 18.5 underweight, 18.5–24.9 healthy weight, 25.0–29.9 overweight, 30.0–34.9 obesity class I, 35.0–39.9 obesity class II and 40 or more obesity class III.
BMI
BMI = 78/1.7² = 26.99
Category
overweight
Answer
overweight
9.Enteral & parenteral nutrition calculations
Answer: %IBW = 144 %
Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.
Ideal body weight (Devine)
162 cm/2.54 = 63.78 in
IBW = 45.5 + 2.3·(63.78 − 60) = 54.19 kg
Percentage of ideal body weight
%IBW = 78/54.19·100 = 143.9 ≈ 144%
Answer
%IBW = 144%
10.Enteral & parenteral nutrition calculations
Answer: GIR = 3.53 mg/kg/min
Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.
Dextrose in the bag
10·1500/100 = 150 g = 150 000 mg
Minutes of infusion
12·60 = 720 min
Glucose infusion rate
GIR = 150 000/(59·720) = 3.531 ≈ 3.53 mg/kg/min
Answer
GIR = 3.53 mg/kg/min
11.ECG rhythm strip interpretation
Answer: QTc = 0.446 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 10 × 0.04 = 0.40 s
RR = 18 × 0.04 = 0.72 s
Fridericia’s formula
QTc = 0.40/∛0.72 = 0.40/0.8963 = 0.446 s
Answer
QTc = 0.446 s
Within the usual limits (about 0.45 s for men, 0.46 s for women). (446 ms)
12.ECG rhythm strip interpretation
Answer: asystole
Ventricular rhythms: ventricular tachycardia is a run of three or more wide (0.12 s or more) complexes in a row at more than 100/min, usually 150–250/min, regular, without related P waves. Ventricular fibrillation is a chaotic, irregular waveform with no identifiable P waves, QRS complexes or T waves and no countable rate. Asystole is an almost flat line with no ventricular activity; a flat line is always confirmed by checking the patient, the leads and the gain and a second lead. In resuscitation guidelines VF and pulseless VT are the shockable rhythms and asystole is not.
Five steps
1. Rate: no countable ventricular rate.
2. Rhythm: none; an almost flat line.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: no QRS complexes.
Interpretation
asystole
Answer
asystole
A flat line is always checked: look at the patient, the leads and the gain, and view a second lead, because a loose electrode or fine VF can look like asystole.
13.Prioritization & delegation
Answer: B · Sit the patient up, lean them forward and pinch the soft part of the nose
Why this is the answer
Leaning forward keeps blood out of the airway and stomach, and firm pressure on the soft part of the nose usually stops the bleeding. Tilting the head back or lying flat lets blood run into the throat.
Answer
B · Sit the patient up, lean them forward and pinch the soft part of the nose
14.Prioritization & delegation
Answer: A · Sudden calf pain and swelling in the operated leg, with new breathlessness
Why this is the answer
Calf pain and swelling suggest deep vein thrombosis, and new breathlessness raises concern for a pulmonary embolism. This needs immediate assessment and escalation; the other findings are expected.
Answer
A · Sudden calf pain and swelling in the operated leg, with new breathlessness
15.Infection control & patient safety
Answer: D · A shower chair, grab bars and a non-slip mat
Why this is the answer
Shower chairs, grab bars and non-slip surfaces reduce slips and falls. Bath oils make surfaces slippery, and a locked door delays help if the person falls.
Answer
D · A shower chair, grab bars and a non-slip mat
16.Infection control & patient safety
Answer: A · Less restrictive measures, such as reorientation and a sitter
Why this is the answer
Less restrictive measures are tried first: reorientation, checking for causes such as pain, securing the tube out of sight and having someone stay with the patient. Restraints or sedatives are used only if these fail and the patient is at risk, with an order.
Answer
A · Less restrictive measures, such as reorientation and a sitter
17.Lab values & electrolytes
Answer: B · Just before the meal, giving insulin when the food is ready
Why this is the answer
Rapid-acting insulin starts working within about 15 minutes, so glucose is checked before the meal and the insulin is given when the meal is available, usually within 15 minutes of eating. Giving it without food can cause hypoglycemia.
Answer
B · Just before the meal, giving insulin when the food is ready
18.Lab values & electrolytes
Answer: A · The supplements are reducing levothyroxine absorption
Why this is the answer
Calcium, iron and antacids bind levothyroxine in the gut and reduce absorption, so the TSH rises. Levothyroxine is taken on an empty stomach, usually 30–60 minutes before breakfast, separated from these supplements by about 4 hours.
Answer
A · The supplements are reducing levothyroxine absorption