Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
Infection control & patient safety
Method
Start with standard precautions for every patient: hand hygiene, PPE for the expected exposure, safe sharps.
Keep sterile items sterile: if in doubt, it is not sterile; replace, never wipe.
Prevent harm in the environment: fall measures, restraints only as a last resort, RACE and PASS for fire.
Check the rights of medication administration, two identifiers and extra safeguards for high-alert drugs; report errors and near misses.
Lab values & electrolytes
Method
Compare the value with the laboratory’s own reference range, then with the patient’s baseline and trend.
Check the sample: hemolysis, a delay, or blood drawn near an IV can give false results.
Link the value to its typical signs and to the drugs and conditions that cause it.
Look for interactions: low potassium or magnesium increases digoxin toxicity; dehydration raises lithium.
Act on the patient: assess, hold a drug if the level is unsafe, read back critical values and inform the prescriber.
2Practice problems
1.Nursing fundamentalsMedium
Which measure is appropriate for a patient with a fever who feels hot and uncomfortable?
ARestricting fluids so the patient sweats less during the fever
BAn ice bath until the patient shivers
CLight bedclothes, plenty of fluids and a prescribed antipyretic
DExtra blankets to make the patient sweat it out
2.Nursing fundamentalsHard
A patient asks for a same-sex nurse for intimate care because of their religious beliefs. What should the nurse do?
AAgree, but only if the patient has a written note from a religious leader
BArrange it where possible and record the preference in the care plan
CRefuse, as all nurses are equally qualified
DTell the patient they must accept whoever is on duty
3.Clinical nursingMedium
Which adverse effects should be monitored for in a patient receiving IV gentamicin?
AConstipation and urinary retention
BHair loss and weight gain
CHyperglycaemia and tremor
DKidney damage and hearing loss
4.Clinical nursingHard
A patient with a tracheostomy suddenly cannot breathe and the tube appears blocked. What is the first action?
ARemove the inner tube (cannula) and check whether it is blocked
BGive oxygen through the mouth only
CDeflate the cuff and leave the patient
DWait for the doctor before doing anything
5.Arterial blood gas interpretationMedium
Practice values: Na⁺ 133 mmol/L, glucose 15.8 mmol/L and urea 6.6 mmol/L. Calculate the serum osmolality Osm = 2·Na⁺ + glucose + urea to the nearest whole number.
Na⁺ 133 mmol/Lglucose 15.8 mmol/Lurea 6.6 mmol/L
Osm = mOsm/kg
6.Arterial blood gas interpretationHard
At sea level, a practice gas taken on 35% oxygen shows PaO₂ 76 mmHg (10.1 kPa) and PaCO₂ 45 mmHg (6.0 kPa). Use PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 to find the A–a gradient.
Practice exercise (made-up values, not clinical guidance). A practice patient is assessed with the Braden scale: sensory perception: no impairment; moisture: rarely moist; activity: bedfast; mobility: slightly limited; nutrition: probably inadequate; friction and shear: problem. Find the Braden total B.
6–23
B =
8.Clinical assessment scoresHard
Practice exercise (made-up values, not clinical guidance). Use the NEWS2 chart (SpO₂ scale 1) for these observations: respiration rate 16/min, SpO₂ 97% on supplemental oxygen, blood pressure 90/54 mmHg, pulse 64/min, alert, temperature 35.8 °C. Which clinical risk group does the patient fall into? Click it.
Practice exercise (made-up values, not clinical guidance). A 79 kg patient has a fluid goal of 30 mL/kg/day and receives all fluid through a feeding tube. The formula is 70% free water and runs at 80 mL/h for 18 hours a day. The rest of the fluid is given as water flushes every 4 hours. What volume V is each flush? Round to the nearest whole number.
Practice exercise (made-up values, not clinical guidance). Over 24 hours a patient receives 1200 mL of parenteral nutrition with final concentrations of 10% dextrose and 4.25% amino acids, plus 100 mL of 20% lipid emulsion (2 kcal/mL). Find the non-protein kilocalorie to nitrogen ratio NPC : N (the number x in x : 1). Round to the nearest whole number.
1200 mLdextrose 10%amino acids 4.25%lipid 100 mL · 2 kcal/mL
NPC : N =
11.ECG rhythm strip interpretationMedium
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Fridericia’s formula QTc = QT/∛RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
12.ECG rhythm strip interpretationHard
This patient has a pacemaker. Interpret the lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1dual-chamber (AV) paced rhythm
2idioventricular rhythm
3sinus rhythm with wide QRS
4paced rhythm, failure to capture
13.Prioritization & delegationMedium
A nurse teaches a patient about sublingual nitroglycerin tablets. Which statement shows a need for further teaching?
A“I will swallow the tablet with a glass of water.”
B“I will keep the tablets in their original dark container.”
C“I may get a headache after taking a tablet.”
D“I will sit down before I take a tablet.”
14.Prioritization & delegationHard
Which patient needs the nurse’s attention first?
AA patient with known migraines who has a headache like their usual ones
BA patient with long-standing hypertension whose blood pressure is 158/94 mmHg and who has no symptoms
CA patient who says this is “the worst headache of my life” that started suddenly, with a blood pressure of 170/100 mmHg
DA patient with chronic back pain asking for a heat pack
15.Infection control & patient safetyMedium
Which type of white blood cell is most often raised in viral infections?
ABasophils
BEosinophils
CLymphocytes
DNeutrophils
16.Infection control & patient safetyHard
A flexible bronchoscope contacts mucous membranes but does not enter sterile tissue. Which level of processing is required at a minimum between patients?
AHigh-level disinfection
BLow-level disinfection
CWiping with an alcohol wipe
DCleaning with soap and water only
17.Lab values & electrolytesMedium
A stool test for Clostridioides difficile is ordered. Which sample is appropriate?
AA formed, hard stool sample
BAny stool after a laxative dose
CA rectal swab from a patient with constipation
DAn unformed (liquid or soft) stool
18.Lab values & electrolytesHard
A patient on long-term amiodarone has fatigue and weight gain. TSH is 11 mIU/L and the free T4 is low. What is the most likely explanation?
ASecondary hypothyroidism from pituitary failure
BAmiodarone-induced hypothyroidism
CAmiodarone-induced hyperthyroidism
DA normal response to amiodarone needing no action
3Solutions
1.Nursing fundamentals
Answer: C · Light bedclothes, plenty of fluids and a prescribed antipyretic
Why this is the answer
Light clothing, fluids and antipyretics such as paracetamol (acetaminophen) increase comfort and replace fluid lost through sweating. Very cold sponging causes shivering, which produces heat.
Answer
C · Light bedclothes, plenty of fluids and a prescribed antipyretic
2.Nursing fundamentals
Answer: B · Arrange it where possible and record the preference in the care plan
Why this is the answer
Respecting such preferences supports dignity and trust. The nurse arranges it whenever possible, records it and explains if it cannot be met in an emergency.
Answer
B · Arrange it where possible and record the preference in the care plan
3.Clinical nursing
Answer: D · Kidney damage and hearing loss
Why this is the answer
Gentamicin is nephrotoxic and ototoxic. Blood levels and renal function are monitored, and any tinnitus, dizziness or hearing change is reported.
Answer
D · Kidney damage and hearing loss
4.Clinical nursing
Answer: A · Remove the inner tube (cannula) and check whether it is blocked
Why this is the answer
Following emergency algorithms, remove the inner cannula first, attempt suction and call for help. If that fails, further steps include cuff deflation and changing the tube.
Answer
A · Remove the inner tube (cannula) and check whether it is blocked
5.Arterial blood gas interpretation
Answer: Osm = 288 mOsm/kg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Calculated osmolality
Osm = 2·133 + 15.8 + 6.6 = 288.4 ≈ 288 mOsm/kg
Answer
Osm = 288 mOsm/kg
6.Arterial blood gas interpretation
Answer: A–a gradient = 117.3 mmHg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Braden scale: six subscales for pressure-injury risk. Sensory perception, moisture, activity, mobility and nutrition score 1 to 4, from the worst level (1) to no problem (4); friction and shear scores 1 to 3. The total runs from 6 to 23, and a lower total means a higher risk. Common bands: 19–23 not at risk, 15–18 mild risk, 13–14 moderate risk, 10–12 high risk and 9 or below very high risk.
Score each subscale
sensory perception: no impairment → 4
moisture: rarely moist → 4
activity: bedfast → 1
mobility: slightly limited → 3
nutrition: probably inadequate → 2
friction and shear: problem → 1
Add
Braden total = 4 + 4 + 1 + 3 + 2 + 1 = 15
Answer
B = 15
8.Clinical assessment scores
Answer: medium
NEWS2 (National Early Warning Score 2, Royal College of Physicians 2017): score each of the seven parameters with the chart (respiration rate, SpO₂ on scale 1, air or supplemental oxygen, systolic blood pressure, pulse, consciousness on the ACVPU scale and temperature) and add the scores. Clinical risk: 0–4 low; a score of 3 in any single parameter low–medium; 5–6 medium; 7 or more high. A total of 5 or more needs an urgent response.
Score each parameter
RR 16/min → 0
SpO₂ 97% → 0
on oxygen → 2
SBP 90 mmHg → 3
HR 64/min → 0
alert (A) → 0
T 35.8 °C → 1
Total and red scores
NEWS2 = 0 + 0 + 2 + 3 + 0 + 0 + 1 = 6
At least one parameter scores 3.
Risk group
medium
Answer
medium
A total of 5 or more calls for an urgent clinical response.
9.Enteral & parenteral nutrition calculations
Answer: V = 227 mL
Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.
Fluid goal
30·79 = 2370 mL/day
Free water from the formula
80·18 = 1440 mL
1440·0.7 = 1008 mL
Water still needed
2370 − 1008 = 1362 mL/day
Volume per flush
24/4 = 6 flushes
V = 1362/6 = 227 mL
Answer
V = 227 mL
10.Enteral & parenteral nutrition calculations
Answer: NPC : N = 75
Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.
Grams of dextrose and amino acids
dextrose: 10·1200/100 = 120 g
amino acids: 4.25·1200/100 = 51 g
Kilocalories per component
dextrose: 120·3.4 = 408 kcal
amino acids: 51·4 = 204 kcal
lipid: 100·2 = 200 kcal
Non-protein kcal and nitrogen
NPC = 408 + 200 = 608 kcal
N = 51/6.25 = 8.16 g
Ratio
NPC : N = 608/8.16 = 74.51 ≈ 75 : 1
Answer
NPC : N = 75
Ratios of about 150 : 1 are typical for stable patients; lower ratios give relatively more protein.
11.ECG rhythm strip interpretation
Answer: QTc = 0.424 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 11 × 0.04 = 0.44 s
RR = 28 × 0.04 = 1.12 s
Fridericia’s formula
QTc = 0.44/∛1.12 = 0.44/1.038 = 0.424 s
Answer
QTc = 0.424 s
Within the usual limits (about 0.45 s for men, 0.46 s for women). (424 ms)
12.ECG rhythm strip interpretation
Answer: dual-chamber (AV) paced rhythm
Paced rhythms: a pacemaker impulse shows as a narrow vertical pacing spike. After a ventricular spike the QRS is wide (0.12 s or more), because the impulse spreads from the lead through the muscle instead of the conduction system; with right-ventricular pacing it is often mostly negative in lead II. A spike before each P wave means atrial pacing, and a dual-chamber (AV) pacemaker shows an atrial spike and a P wave, then, after the programmed AV delay, a ventricular spike and a wide QRS. Capture means every spike is followed by a depolarisation. Failure to capture is a spike without a P wave or QRS after it; failure to sense (spikes that ignore the patient’s own beats) and failure to pace (no spike when one is due) are the other classic malfunctions.
Five steps
1. Rate: R–R = 22 small boxes, 1500 ÷ 22 ≈ 68 per minute.
2. Rhythm: regular, every R–R is 0.88 s.
3. P waves: each P wave follows its own pacing spike (atrial pacing).
4. AV interval: the second spike comes 0.20 s after the first one (the programmed AV delay).
5. QRS: 0.16 s, wide, right after the second spike (ventricular pacing).
Interpretation
dual-chamber (AV) paced rhythm
Answer
dual-chamber (AV) paced rhythm
The paced QRS is wide by nature; do not call it a bundle branch block or a ventricular rhythm.
13.Prioritization & delegation
Answer: A · “I will swallow the tablet with a glass of water.”
Why this is the answer
Sublingual tablets dissolve under the tongue and are absorbed quickly there. Sitting down reduces falls from low blood pressure, the tablets are protected from light and moisture, and headache is a common side effect.
Answer
A · “I will swallow the tablet with a glass of water.”
14.Prioritization & delegation
Answer: C · A patient who says this is “the worst headache of my life” that started suddenly, with a blood pressure of 170/100 mmHg
Why this is the answer
A sudden, severe “thunderclap” headache can mean a bleed in the brain, such as a subarachnoid hemorrhage, and is an emergency. The other patients have known, stable problems that match their history.
Answer
C · A patient who says this is “the worst headache of my life” that started suddenly, with a blood pressure of 170/100 mmHg
15.Infection control & patient safety
Answer: C · Lymphocytes
Why this is the answer
Lymphocytes increase in many viral infections. Neutrophils rise mainly with bacterial infections, and eosinophils with allergies and parasites.
Answer
C · Lymphocytes
16.Infection control & patient safety
Answer: A · High-level disinfection
Why this is the answer
Items that touch mucous membranes or non-intact skin are semi-critical and need at least high-level disinfection after thorough cleaning. Inadequate reprocessing of endoscopes has caused outbreaks.
Answer
A · High-level disinfection
17.Lab values & electrolytes
Answer: D · An unformed (liquid or soft) stool
Why this is the answer
C. difficile testing is done on unformed stool from patients with diarrhea, because many people carry the organism without disease. Testing formed stool, or stool after laxatives, can lead to misdiagnosis.Checked against:C. diff Testing · MedlinePlus (NIH) (2026)
Answer
D · An unformed (liquid or soft) stool
18.Lab values & electrolytes
Answer: B · Amiodarone-induced hypothyroidism
Why this is the answer
Amiodarone is rich in iodine and can cause either hypothyroidism or hyperthyroidism. A high TSH with a low free T4 shows primary hypothyroidism, so thyroid function is monitored before and during therapy; liver tests are monitored too.Checked against:Hypothyroidism · MedlinePlus (NIH) (2024)