Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
falls 25, diagnosis 15, aid 15/30, IV 20, gait 10/20, mental status 15
NEWS2 risk
0–4 low; single 3 low–medium; 5–6 medium; ≥ 7 high
Mean arterial pressure
MAP = (SBP + 2·DBP)/3 = DBP + PP/3
Pulse pressure and shock index
PP = SBP − DBP, SI = HR/SBP
Body mass index
BMI = kg/m² = 703·lb/in²
Method
Find the score sheet that the question uses and its range (GCS 3–15, APGAR 0–10, Braden 6–23, Morse 0–125).
Score every item separately, matching the description to its level.
Add the item scores and check that the total lies inside the range.
Apply the cut-offs: for NEWS2 also look for any single parameter scoring 3.
For derived values use MAP = (SBP + 2·DBP)/3, PP = SBP − DBP, SI = HR/SBP and BMI = kg/m².
Med-surg: cardiovascular & respiratory
Method
Name the problem: pump failure, blocked artery, rhythm, clot, airway narrowing, infection or a device problem.
Check the danger signs first: hypoxia, hypotension, chest pain, new confusion, a cold pulseless limb.
Match the oxygen to the patient: 94–98% for most, 88–92% for those at risk of CO₂ retention.
Link each drug to its test and its risk: warfarin and INR, heparin and aPTT and platelets, diuretics and potassium.
Choose the safe first action, then escalate and reassess.
2Practice problems
1.Oxygen therapy & respiratory calculationsMedium
Practice exercise (made-up values, not clinical guidance). A size E oxygen cylinder (factor 0.28 L/psi) reads 900 psi and runs at 6 L/min. Keeping a safe residual of 200 psi, how many minutes t will it last? Round down to a whole minute.
900 psif = 0.28 L/psi6 L/min200 psi
t = min
2.Oxygen therapy & respiratory calculationsHard
Practice exercise (made-up values, not clinical guidance). A ventilated woman is 162 cm tall and weighs 81 kg. Lung-protective ventilation is set at 4 mL per kg of predicted body weight. Using PBW = 45.5 + 0.91 × (height cm − 152.4) kg, find the tidal volume VT to the nearest mL.
162 cm81 kg4 mL/kg
VT = mL
3.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.64, PaCO₂ 23 mmHg (3.1 kPa) and HCO₃⁻ 24 mmol/L. The primary disorder is respiratory alkalosis. How far is it compensated? Click your answer.
pH 7.64PaCO₂ 23 mmHg (3.1 kPa)HCO₃⁻ 24 mmol/L
1uncompensated
2partially compensated
3fully compensated
4.Arterial blood gas interpretationHard
At sea level, a practice gas taken on 24% oxygen shows PaO₂ 60 mmHg (8.0 kPa) and PaCO₂ 47 mmHg (6.3 kPa). Use PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 to find the A–a gradient.
Practice exercise (made-up values, not clinical guidance). A practice patient is assessed with the Braden scale: sensory perception: slightly limited; moisture: constantly moist; activity: bedfast; mobility: very limited; nutrition: very poor; friction and shear: no apparent problem. Find the Braden total B.
6–23
B =
6.Clinical assessment scoresHard
Practice exercise (made-up values, not clinical guidance). An adult weighs 126 kg and is 175 cm tall. Calculate the BMI and click the WHO weight category.
126 kg175 cm
1underweight
2healthy weight
3overweight
4obesity class I
5obesity class II
6obesity class III
7.Med-surg: cardiovascular & respiratoryMedium
A patient has pneumonia in the right lung only. In which side-lying position will oxygenation usually be best?
AFlat on the back with no pillows
BLying on the left side, with the healthy lung down
CLying on the right side, with the affected lung down
DProne with the head down
8.Med-surg: cardiovascular & respiratoryHard
A patient with obstructive sleep apnoea who uses CPAP at home is having surgery. Which plan is safest after the operation?
ANurse the patient lying flat on their back to keep the airway open
BUse their CPAP machine and monitor closely, using opioids with caution
CGive extra opioids so the patient sleeps through the night
DLeave the CPAP machine at home, as it is not needed while in hospital
3Solutions
1.Oxygen therapy & respiratory calculations
Answer: t = 32 min
Cylinder duration: usable litres = (gauge pressure − safe residual) × cylinder factor, with the safe residual usually 200 psi. Cylinder factors in L/psi: D 0.16, E 0.28, H (and K) 3.14. Duration (min) = usable litres/flow (L/min). Round a duration down, never up, so the cylinder is changed in time. In bar-based systems, the gas volume is the water capacity (L) × the pressure (bar).
Usable litres
(900 − 200)·0.28 = 196 L
Duration
196/6 = 32.67 min → t = 32 min
Answer
t = 32 min
2.Oxygen therapy & respiratory calculations
Answer: VT = 217 mL
Ventilation: minute ventilation V̇E = tidal volume × respiratory rate (normal adult about 5–8 L/min). Alveolar ventilation V̇A = (tidal volume − dead space) × rate, because the air in the airways (about 150 mL in an adult) takes no part in gas exchange. Lung-protective ventilation uses about 6 mL per kg of predicted body weight (PBW): men 50 + 0.91 × (height in cm − 152.4) kg, women 45.5 + 0.91 × (height in cm − 152.4) kg (with inches: 2.3 per inch above 60 in).
Predicted body weight
PBW = 45.5 + 0.91·(162 − 152.4) = 54.24 kg
Tidal volume
VT = 4·54.24 = 216.9 ≈ 217 mL
Answer
VT = 217 mL
3.Arterial blood gas interpretation
Answer: uncompensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.64: alkalaemia (above 7.45)
PaCO₂ 23 mmHg: low (35–45)
HCO₃⁻ 24 mmol/L: normal (22–26)
Compensation
uncompensated
Answer
uncompensated
4.Arterial blood gas interpretation
Answer: A–a gradient = 52.37 mmHg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Braden scale: six subscales for pressure-injury risk. Sensory perception, moisture, activity, mobility and nutrition score 1 to 4, from the worst level (1) to no problem (4); friction and shear scores 1 to 3. The total runs from 6 to 23, and a lower total means a higher risk. Common bands: 19–23 not at risk, 15–18 mild risk, 13–14 moderate risk, 10–12 high risk and 9 or below very high risk.
Score each subscale
sensory perception: slightly limited → 3
moisture: constantly moist → 1
activity: bedfast → 1
mobility: very limited → 2
nutrition: very poor → 1
friction and shear: no apparent problem → 3
Add
Braden total = 3 + 1 + 1 + 2 + 1 + 3 = 11
Answer
B = 11
6.Clinical assessment scores
Answer: obesity class III
Body mass index: BMI = weight (kg)/height (m)², with the height converted to metres first. With pounds and inches, BMI = 703 × weight (lb)/height (in)². WHO adult categories: below 18.5 underweight, 18.5–24.9 healthy weight, 25.0–29.9 overweight, 30.0–34.9 obesity class I, 35.0–39.9 obesity class II and 40 or more obesity class III.
BMI
BMI = 126/1.75² = 41.14
Category
obesity class III
Answer
obesity class III
7.Med-surg: cardiovascular & respiratory
Answer: B · Lying on the left side, with the healthy lung down
Why this is the answer
Blood flow goes preferentially to the dependent lung. Placing the healthy lung down matches more blood to the well-ventilated lung, improving oxygenation ("good lung down"). Exceptions include a lung abscess or bleeding, when the affected lung is placed down to protect the healthy one.
Answer
B · Lying on the left side, with the healthy lung down
8.Med-surg: cardiovascular & respiratory
Answer: B · Use their CPAP machine and monitor closely, using opioids with caution
Why this is the answer
Sedatives and opioids worsen airway collapse in OSA. Patients should bring and use their CPAP after surgery, be monitored with pulse oximetry, have opioid-sparing analgesia where possible and be nursed semi-upright or on their side.
Answer
B · Use their CPAP machine and monitor closely, using opioids with caution