Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
falls 25, diagnosis 15, aid 15/30, IV 20, gait 10/20, mental status 15
NEWS2 risk
0–4 low; single 3 low–medium; 5–6 medium; ≥ 7 high
Mean arterial pressure
MAP = (SBP + 2·DBP)/3 = DBP + PP/3
Pulse pressure and shock index
PP = SBP − DBP, SI = HR/SBP
Body mass index
BMI = kg/m² = 703·lb/in²
Method
Find the score sheet that the question uses and its range (GCS 3–15, APGAR 0–10, Braden 6–23, Morse 0–125).
Score every item separately, matching the description to its level.
Add the item scores and check that the total lies inside the range.
Apply the cut-offs: for NEWS2 also look for any single parameter scoring 3.
For derived values use MAP = (SBP + 2·DBP)/3, PP = SBP − DBP, SI = HR/SBP and BMI = kg/m².
Med-surg: cardiovascular & respiratory
Method
Name the problem: pump failure, blocked artery, rhythm, clot, airway narrowing, infection or a device problem.
Check the danger signs first: hypoxia, hypotension, chest pain, new confusion, a cold pulseless limb.
Match the oxygen to the patient: 94–98% for most, 88–92% for those at risk of CO₂ retention.
Link each drug to its test and its risk: warfarin and INR, heparin and aPTT and platelets, diuretics and potassium.
Choose the safe first action, then escalate and reassess.
2Practice problems
1.Oxygen therapy & respiratory calculationsMedium
Practice exercise (made-up values, not clinical guidance). A size H oxygen cylinder (factor 3.14 L/psi) reads 1950 psi and runs at 10 L/min. Keeping a safe residual of 200 psi, how many minutes t will it last? Round down to a whole minute.
1950 psif = 3.14 L/psi10 L/min200 psi
t = min
2.Oxygen therapy & respiratory calculationsHard
Practice exercise (made-up values, not clinical guidance). A transfer will take 90 minutes. The size E cylinder (factor 0.28 L/psi) reads 2200 psi. Keeping a safe residual of 200 psi, what is the highest whole-number flow Q in L/min that lasts the whole transfer?
90 min2200 psif = 0.28 L/psi200 psi
Q = L/min
3.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.44, PaCO₂ 20 mmHg (2.7 kPa) and HCO₃⁻ 13 mmol/L. The primary disorder is respiratory alkalosis. How far is it compensated? Click your answer.
pH 7.44PaCO₂ 20 mmHg (2.7 kPa)HCO₃⁻ 13 mmol/L
1uncompensated
2partially compensated
3fully compensated
4.Arterial blood gas interpretationHard
A practice gas shows a metabolic alkalosis with HCO₃⁻ 32 mmol/L. Use expected PaCO₂ = 0.7·HCO₃⁻ + 21 to find the expected PaCO₂.
HCO₃⁻ 32 mmol/L
PaCO₂ = mmHg
5.Clinical assessment scoresMedium
Practice exercise (made-up values, not clinical guidance). A practice chart records GCS 13, with E4 and V4. What motor score M was recorded, and which response does it describe? Give the number.
GCS 13E4V4
M =
6.Clinical assessment scoresHard
Practice exercise (made-up values, not clinical guidance). Use the NEWS2 chart (SpO₂ scale 1) for these observations: respiration rate 12/min, SpO₂ 92% on supplemental oxygen, blood pressure 136/82 mmHg, pulse 130/min, alert, temperature 37.4 °C. Which clinical risk group does the patient fall into? Click it.
RR 12SpO₂ 92%O₂SBP 136HR 130AT 37.4 °C
1low
2low–medium
3medium
4high
7.Med-surg: cardiovascular & respiratoryMedium
A patient with asthma uses their reliever inhaler more than three times a week. What does this suggest?
AThe reliever no longer works and should be stopped
BAsthma is well controlled with the current plan
CAsthma control is poor and treatment needs review
DThe preventer inhaler is no longer needed
8.Med-surg: cardiovascular & respiratoryHard
A patient is going home after a spontaneous pneumothorax treated with a chest drain. Which advice is correct?
AExpect it never to happen again, so no follow-up is needed
BTake up scuba diving to strengthen the lungs
CFly home as soon as possible so they can recover in comfort there
DStop smoking and do not fly until a doctor confirms full resolution
3Solutions
1.Oxygen therapy & respiratory calculations
Answer: t = 549 min
Cylinder duration: usable litres = (gauge pressure − safe residual) × cylinder factor, with the safe residual usually 200 psi. Cylinder factors in L/psi: D 0.16, E 0.28, H (and K) 3.14. Duration (min) = usable litres/flow (L/min). Round a duration down, never up, so the cylinder is changed in time. In bar-based systems, the gas volume is the water capacity (L) × the pressure (bar).
Usable litres
(1950 − 200)·3.14 = 5495 L
Duration
5495/10 = 549.5 min → t = 549 min
Answer
t = 549 min
That is about 9 h 09 min.
2.Oxygen therapy & respiratory calculations
Answer: Q = 6 L/min
Cylinder duration: usable litres = (gauge pressure − safe residual) × cylinder factor, with the safe residual usually 200 psi. Cylinder factors in L/psi: D 0.16, E 0.28, H (and K) 3.14. Duration (min) = usable litres/flow (L/min). Round a duration down, never up, so the cylinder is changed in time. In bar-based systems, the gas volume is the water capacity (L) × the pressure (bar).
Usable litres
(2200 − 200)·0.28 = 560 L
Highest flow
560/90 = 6.222 L/min → Q = 6 L/min
Answer
Q = 6 L/min
3.Arterial blood gas interpretation
Answer: fully compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.44: within 7.35–7.45
PaCO₂ 20 mmHg: low (35–45)
HCO₃⁻ 13 mmol/L: low (22–26)
Compensation
fully compensated
Answer
fully compensated
4.Arterial blood gas interpretation
Answer: PaCO₂ = 43.4 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
0.7·32 + 21 = 43.4 mmHg
Answer
PaCO₂ = 43.4 mmHg
The rise has a limit: PaCO₂ rarely goes above about 55 mmHg from compensation alone.
5.Clinical assessment scores
Answer: M = 5
Glasgow Coma Scale: add the best response in three areas. Eye opening E: 4 spontaneous, 3 to sound or speech, 2 to pressure, 1 none. Verbal V: 5 oriented, 4 confused, 3 inappropriate words, 2 incomprehensible sounds, 1 none. Motor M: 6 obeys commands, 5 localises, 4 normal flexion (withdraws), 3 abnormal flexion, 2 extension, 1 none. The total runs from 3 to 15. After a head injury, 13–15 is usually called mild, 9–12 moderate and 3–8 severe.
Motor score
M = 13 − 4 − 4 = 5
M5: moves a hand to the site of pressure (localises)
Answer
M = 5
6.Clinical assessment scores
Answer: medium
NEWS2 (National Early Warning Score 2, Royal College of Physicians 2017): score each of the seven parameters with the chart (respiration rate, SpO₂ on scale 1, air or supplemental oxygen, systolic blood pressure, pulse, consciousness on the ACVPU scale and temperature) and add the scores. Clinical risk: 0–4 low; a score of 3 in any single parameter low–medium; 5–6 medium; 7 or more high. A total of 5 or more needs an urgent response.
Score each parameter
RR 12/min → 0
SpO₂ 92% → 2
on oxygen → 2
SBP 136 mmHg → 0
HR 130/min → 2
alert (A) → 0
T 37.4 °C → 0
Total and red scores
NEWS2 = 0 + 2 + 2 + 0 + 2 + 0 + 0 = 6
No parameter scores 3.
Risk group
medium
Answer
medium
A total of 5 or more calls for an urgent clinical response.
7.Med-surg: cardiovascular & respiratory
Answer: C · Asthma control is poor and treatment needs review
Why this is the answer
Needing a reliever often, waking at night with symptoms or limiting activity indicates poorly controlled asthma. Inhaler technique, adherence and triggers should be checked and the regular preventer treatment stepped up.
Answer
C · Asthma control is poor and treatment needs review
8.Med-surg: cardiovascular & respiratory
Answer: D · Stop smoking and do not fly until a doctor confirms full resolution
Why this is the answer
Patients should not fly until the pneumothorax has resolved on X-ray, often with an extra waiting period. Diving is usually avoided permanently unless definitive surgery has been done. Smoking increases recurrence, which is common, so patients learn to seek help for new breathlessness or chest pain.
Answer
D · Stop smoking and do not fly until a doctor confirms full resolution