Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
falls 25, diagnosis 15, aid 15/30, IV 20, gait 10/20, mental status 15
NEWS2 risk
0–4 low; single 3 low–medium; 5–6 medium; ≥ 7 high
Mean arterial pressure
MAP = (SBP + 2·DBP)/3 = DBP + PP/3
Pulse pressure and shock index
PP = SBP − DBP, SI = HR/SBP
Body mass index
BMI = kg/m² = 703·lb/in²
Method
Find the score sheet that the question uses and its range (GCS 3–15, APGAR 0–10, Braden 6–23, Morse 0–125).
Score every item separately, matching the description to its level.
Add the item scores and check that the total lies inside the range.
Apply the cut-offs: for NEWS2 also look for any single parameter scoring 3.
For derived values use MAP = (SBP + 2·DBP)/3, PP = SBP − DBP, SI = HR/SBP and BMI = kg/m².
Med-surg: cardiovascular & respiratory
Method
Name the problem: pump failure, blocked artery, rhythm, clot, airway narrowing, infection or a device problem.
Check the danger signs first: hypoxia, hypotension, chest pain, new confusion, a cold pulseless limb.
Match the oxygen to the patient: 94–98% for most, 88–92% for those at risk of CO₂ retention.
Link each drug to its test and its risk: warfarin and INR, heparin and aPTT and platelets, diuretics and potassium.
Choose the safe first action, then escalate and reassess.
2Practice problems
1.Oxygen therapy & respiratory calculationsMedium
Practice exercise (made-up values, not clinical guidance). A patient has Hb 156 g/L, SaO₂ 92% and PaO₂ 63 mmHg (8.4 kPa). Find the arterial oxygen content CaO₂ = 1.34 × Hb (g/dL) × SaO₂ + 0.003 × PaO₂ (mmHg) in mL O₂/dL.
Hb 156 g/LSaO₂ 92%PaO₂ 63 mmHg (8.4 kPa)
CaO₂ = mL/dL
2.Oxygen therapy & respiratory calculationsHard
Practice exercise (made-up values, not clinical guidance). A ventilated man is 186 cm tall and weighs 93 kg. Lung-protective ventilation is set at 4 mL per kg of predicted body weight. Using PBW = 50 + 0.91 × (height cm − 152.4) kg, find the tidal volume VT to the nearest mL.
186 cm93 kg4 mL/kg
VT = mL
3.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.48, PaCO₂ 43 mmHg (5.7 kPa) and HCO₃⁻ 31 mmol/L. The primary disorder is metabolic alkalosis. How far is it compensated? Click your answer.
pH 7.48PaCO₂ 43 mmHg (5.7 kPa)HCO₃⁻ 31 mmol/L
1uncompensated
2partially compensated
3fully compensated
4.Arterial blood gas interpretationHard
Practice values: Na⁺ 143, Cl⁻ 113, HCO₃⁻ 12 mmol/L and albumin 22 g/L. Find the albumin-corrected anion gap AGc = AG + 0.25·(40 − albumin).
Practice exercise (made-up values, not clinical guidance). A practice patient is assessed with the Morse fall scale: history of falling in the last 3 months: yes; secondary diagnosis: no; ambulatory aid: holds on to furniture; IV therapy or saline lock: no; gait: impaired; mental status: knows own limits. Find the Morse total MFS.
0–125
MFS =
6.Clinical assessment scoresHard
Practice exercise (made-up values, not clinical guidance). A practice patient is assessed with the Braden scale: sensory perception: no impairment; moisture: occasionally moist; activity: chairfast; mobility: completely immobile; nutrition: excellent; friction and shear: potential problem. Use the bands 19–23 not at risk, 15–18 mild, 13–14 moderate, 10–12 high and 9 or below very high. Click the risk level.
1not at risk
2mild risk
3moderate risk
4high risk
5very high risk
7.Med-surg: cardiovascular & respiratoryMedium
The fluid in a chest drain has stopped swinging. What could this mean?
AThe drainage unit has started draining the abdomen
BThe lung has re-expanded, or the tube is kinked or blocked
CThe water level in the chamber is now too high to move
DA new pneumothorax has developed on the other side
8.Med-surg: cardiovascular & respiratoryHard
A patient who has had a total laryngectomy becomes breathless and needs oxygen. How should it be given?
AVia a mask or humidified device over the neck stoma
BVia nasal cannula at 2 L/min
CVia a standard face mask over the nose and mouth
DVia a non-rebreather mask over the mouth only
3Solutions
1.Oxygen therapy & respiratory calculations
Answer: CaO₂ = 19.42 mL/dL
Oxygen content and delivery: CaO₂ = 1.34 × Hb (g/dL) × SaO₂ + 0.003 × PaO₂ (mmHg), in mL O₂ per dL of blood, with SaO₂ as a fraction. Almost all oxygen is bound to haemoglobin; the dissolved part is small. Delivery DO₂ = CaO₂ × cardiac output (L/min) × 10 (mL/min), because 1 L = 10 dL; a normal resting adult value is about 1000 mL/min.
Hb in g/dL
156 g/L = 15.6 g/dL
Bound oxygen
1.34·15.6·0.92 = 19.23 mL/dL
Dissolved oxygen
0.003·63 = 0.189 mL/dL
Oxygen content
CaO₂ = 19.23 + 0.189 = 19.42 mL/dL
Answer
CaO₂ = 19.42 mL/dL
2.Oxygen therapy & respiratory calculations
Answer: VT = 322 mL
Ventilation: minute ventilation V̇E = tidal volume × respiratory rate (normal adult about 5–8 L/min). Alveolar ventilation V̇A = (tidal volume − dead space) × rate, because the air in the airways (about 150 mL in an adult) takes no part in gas exchange. Lung-protective ventilation uses about 6 mL per kg of predicted body weight (PBW): men 50 + 0.91 × (height in cm − 152.4) kg, women 45.5 + 0.91 × (height in cm − 152.4) kg (with inches: 2.3 per inch above 60 in).
Predicted body weight
PBW = 50 + 0.91·(186 − 152.4) = 80.58 kg
Tidal volume
VT = 4·80.58 = 322.3 ≈ 322 mL
Answer
VT = 322 mL
3.Arterial blood gas interpretation
Answer: uncompensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.48: alkalaemia (above 7.45)
PaCO₂ 43 mmHg: normal (35–45)
HCO₃⁻ 31 mmol/L: high (22–26)
Compensation
uncompensated
Answer
uncompensated
4.Arterial blood gas interpretation
Answer: AGc = 22.5 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 143 − (113 + 12) = 18
Correction for albumin
18 + 0.25·(40 − 22) = 22.5 mmol/L
Answer
AGc = 22.5 mmol/L
Above about 12 after correction: a high anion gap.
5.Clinical assessment scores
Answer: MFS = 75
Morse fall scale: six items. History of falling: no 0, yes 25. Secondary diagnosis: no 0, yes 15. Ambulatory aid: none, bed rest or nurse assistance 0; crutches, cane or walker 15; holding on to furniture 30. IV therapy or saline lock: no 0, yes 20. Gait: normal, bed rest or wheelchair 0; weak 10; impaired 20. Mental status: knows own limits 0; overestimates or forgets limits 15. The total runs from 0 to 125. Risk cut-offs differ between hospitals; a common set is 0–24 low, 25–44 moderate and 45 or more high.
Score each item
history of falling in the last 3 months: yes → 25
secondary diagnosis: no → 0
ambulatory aid: holds on to furniture → 30
IV therapy or saline lock: no → 0
gait: impaired → 20
mental status: knows own limits → 0
Add
Morse total = 25 + 0 + 30 + 0 + 20 + 0 = 75
Answer
MFS = 75
6.Clinical assessment scores
Answer: mild risk
Braden scale: six subscales for pressure-injury risk. Sensory perception, moisture, activity, mobility and nutrition score 1 to 4, from the worst level (1) to no problem (4); friction and shear scores 1 to 3. The total runs from 6 to 23, and a lower total means a higher risk. Common bands: 19–23 not at risk, 15–18 mild risk, 13–14 moderate risk, 10–12 high risk and 9 or below very high risk.
Score each subscale
sensory perception: no impairment → 4
moisture: occasionally moist → 3
activity: chairfast → 2
mobility: completely immobile → 1
nutrition: excellent → 4
friction and shear: potential problem → 2
Add
Braden total = 4 + 3 + 2 + 1 + 4 + 2 = 16
Risk level
16 → mild risk
Answer
mild risk
7.Med-surg: cardiovascular & respiratory
Answer: B · The lung has re-expanded, or the tube is kinked or blocked
Why this is the answer
Loss of swinging can occur when the lung fully re-expands and seals the tube, but also when the tube is kinked, clotted or the patient is lying on it. Assess the patient and the tubing, and report it.
Answer
B · The lung has re-expanded, or the tube is kinked or blocked
8.Med-surg: cardiovascular & respiratory
Answer: A · Via a mask or humidified device over the neck stoma
Why this is the answer
A total laryngectomy separates the trachea from the upper airway, so the patient breathes only through the neck stoma. Oxygen and any rescue breaths must be given via the stoma. These patients are "neck breathers" and often carry an alert card.
Answer
A · Via a mask or humidified device over the neck stoma