Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
falls 25, diagnosis 15, aid 15/30, IV 20, gait 10/20, mental status 15
NEWS2 risk
0–4 low; single 3 low–medium; 5–6 medium; ≥ 7 high
Mean arterial pressure
MAP = (SBP + 2·DBP)/3 = DBP + PP/3
Pulse pressure and shock index
PP = SBP − DBP, SI = HR/SBP
Body mass index
BMI = kg/m² = 703·lb/in²
Method
Find the score sheet that the question uses and its range (GCS 3–15, APGAR 0–10, Braden 6–23, Morse 0–125).
Score every item separately, matching the description to its level.
Add the item scores and check that the total lies inside the range.
Apply the cut-offs: for NEWS2 also look for any single parameter scoring 3.
For derived values use MAP = (SBP + 2·DBP)/3, PP = SBP − DBP, SI = HR/SBP and BMI = kg/m².
Med-surg: cardiovascular & respiratory
Method
Name the problem: pump failure, blocked artery, rhythm, clot, airway narrowing, infection or a device problem.
Check the danger signs first: hypoxia, hypotension, chest pain, new confusion, a cold pulseless limb.
Match the oxygen to the patient: 94–98% for most, 88–92% for those at risk of CO₂ retention.
Link each drug to its test and its risk: warfarin and INR, heparin and aPTT and platelets, diuretics and potassium.
Choose the safe first action, then escalate and reassess.
2Practice problems
1.Oxygen therapy & respiratory calculationsMedium
Practice exercise (made-up values, not clinical guidance). A patient has Hb 166 g/L, SaO₂ 96% and PaO₂ 81 mmHg (10.8 kPa). Find the arterial oxygen content CaO₂ = 1.34 × Hb (g/dL) × SaO₂ + 0.003 × PaO₂ (mmHg) in mL O₂/dL.
Hb 166 g/LSaO₂ 96%PaO₂ 81 mmHg (10.8 kPa)
CaO₂ = mL/dL
2.Oxygen therapy & respiratory calculationsHard
Practice exercise (made-up values, not clinical guidance). A cylinder with a water capacity of 3 L is filled to 69 bar and runs at 12 L/min. The gas volume is about the water capacity × the pressure. In this exercise the cylinder is changed at 20 bar. How many minutes t until it must be changed? Round down to a whole minute.
3 L69 bar12 L/min20 bar
t = min
3.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.50, PaCO₂ 49 mmHg (6.5 kPa) and HCO₃⁻ 37 mmol/L. The primary disorder is metabolic alkalosis. How far is it compensated? Click your answer.
pH 7.50PaCO₂ 49 mmHg (6.5 kPa)HCO₃⁻ 37 mmol/L
1uncompensated
2partially compensated
3fully compensated
4.Arterial blood gas interpretationHard
At sea level, a practice gas taken on 40% oxygen shows PaO₂ 53 mmHg (7.1 kPa) and PaCO₂ 56 mmHg (7.5 kPa). Use PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 to find the A–a gradient.
Practice exercise (made-up values, not clinical guidance). A practice patient after a head injury opens the eyes only to pressure (a painful stimulus), says inappropriate, random words and shows as the best motor response: moves a hand to the site of pressure (localises). Work out the GCS and classify the head injury by it. Click your answer.
1mild
2moderate
3severe
6.Clinical assessment scoresHard
Practice exercise (made-up values, not clinical guidance). At 5 minutes after birth, a practice newborn has pink skin all over, a heart rate of 155/min, a grimace when stimulated, some flexion of the arms and legs and good breathing with a strong cry. Score the APGAR and click how the score is interpreted.
1reassuring
2moderately abnormal
3low
7.Med-surg: cardiovascular & respiratoryMedium
After coronary artery bypass surgery through a median sternotomy, which instruction is usually given for the first several weeks?
ASleep only on the stomach to protect the wound
BLift the arms above the head often to stretch the chest
CAvoid heavy lifting and pushing up with the arms
DAvoid walking until the stitches are removed
8.Med-surg: cardiovascular & respiratoryHard
On day 2 after a surgical tracheostomy, the tube falls out. The patient is breathing but distressed. What should the nurse do first?
ACall for expert help and give oxygen to both the face and the stoma
BForce the tube back through the stoma immediately with firm pressure
CLeave the patient alone while fetching a new tube
DCover the stoma completely with a sealed dressing and wait for help
3Solutions
1.Oxygen therapy & respiratory calculations
Answer: CaO₂ = 21.6 mL/dL
Oxygen content and delivery: CaO₂ = 1.34 × Hb (g/dL) × SaO₂ + 0.003 × PaO₂ (mmHg), in mL O₂ per dL of blood, with SaO₂ as a fraction. Almost all oxygen is bound to haemoglobin; the dissolved part is small. Delivery DO₂ = CaO₂ × cardiac output (L/min) × 10 (mL/min), because 1 L = 10 dL; a normal resting adult value is about 1000 mL/min.
Hb in g/dL
166 g/L = 16.6 g/dL
Bound oxygen
1.34·16.6·0.96 = 21.35 mL/dL
Dissolved oxygen
0.003·81 = 0.243 mL/dL
Oxygen content
CaO₂ = 21.35 + 0.243 = 21.6 mL/dL
Answer
CaO₂ = 21.6 mL/dL
2.Oxygen therapy & respiratory calculations
Answer: t = 12 min
Cylinder duration: usable litres = (gauge pressure − safe residual) × cylinder factor, with the safe residual usually 200 psi. Cylinder factors in L/psi: D 0.16, E 0.28, H (and K) 3.14. Duration (min) = usable litres/flow (L/min). Round a duration down, never up, so the cylinder is changed in time. In bar-based systems, the gas volume is the water capacity (L) × the pressure (bar).
Usable gas
3·(69 − 20) = 147 L
Duration
147/12 = 12.25 min → t = 12 min
Answer
t = 12 min
3.Arterial blood gas interpretation
Answer: partially compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.50: alkalaemia (above 7.45)
PaCO₂ 49 mmHg: high (35–45)
HCO₃⁻ 37 mmol/L: high (22–26)
Compensation
Clinically, also check the expected compensation: for a metabolic alkalosis PaCO₂ ≈ 0.7·HCO₃⁻ + 21 = 44.9–48.9 mmHg, so the measured 49 mmHg points to an additional respiratory acidosis (a mixed disorder). The answer above is the ROME exam classification.
partially compensated
Answer
partially compensated
4.Arterial blood gas interpretation
Answer: A–a gradient = 162.2 mmHg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Alveolar oxygen
PAO₂ = 0.4·713 − 56/0.8 = 285.2 − 70 = 215.2 mmHg
Gradient
A–a = 215.2 − 53 = 162.2 mmHg
Answer
A–a gradient = 162.2 mmHg
5.Clinical assessment scores
Answer: moderate
Glasgow Coma Scale: add the best response in three areas. Eye opening E: 4 spontaneous, 3 to sound or speech, 2 to pressure, 1 none. Verbal V: 5 oriented, 4 confused, 3 inappropriate words, 2 incomprehensible sounds, 1 none. Motor M: 6 obeys commands, 5 localises, 4 normal flexion (withdraws), 3 abnormal flexion, 2 extension, 1 none. The total runs from 3 to 15. After a head injury, 13–15 is usually called mild, 9–12 moderate and 3–8 severe.
Score each area
E: opens the eyes only to pressure (a painful stimulus) → 2
V: says inappropriate, random words → 3
M: moves a hand to the site of pressure (localises) → 5
Add
GCS = 2 + 3 + 5 = 10
Severity
GCS 10 → moderate
Answer
moderate
6.Clinical assessment scores
Answer: reassuring
APGAR score: five signs, each scored 0, 1 or 2, checked at 1 and 5 minutes after birth. Appearance (colour): blue or pale 0, pink body with blue extremities 1, pink all over 2. Pulse: absent 0, below 100/min 1, 100/min or more 2. Grimace (reflex irritability): none 0, grimace 1, cry, cough or sneeze 2. Activity (tone): limp 0, some flexion 1, active movement 2. Respiration: absent 0, slow or irregular with a weak cry 1, good with a strong cry 2. A total of 7–10 is reassuring, 4–6 moderately abnormal and 0–3 low.
Score each sign
Appearance: pink skin all over → 2
Pulse: 155/min → 2
Grimace: a grimace when stimulated → 1
Activity: some flexion of the arms and legs → 1
Respiration: good breathing with a strong cry → 2
Add
APGAR = 2 + 2 + 1 + 1 + 2 = 8
Interpretation
8 → reassuring
Answer
reassuring
7.Med-surg: cardiovascular & respiratory
Answer: C · Avoid heavy lifting and pushing up with the arms
Why this is the answer
The sternum is wired and takes weeks to heal. Patients are advised to avoid heavy lifting, pulling and pushing with the arms, and to support the chest with a pillow when coughing. Walking is encouraged as part of cardiac rehabilitation.
Answer
C · Avoid heavy lifting and pushing up with the arms
8.Med-surg: cardiovascular & respiratory
Answer: A · Call for expert help and give oxygen to both the face and the stoma
Why this is the answer
In the first days after a tracheostomy, the tract is immature and the tube can easily be misplaced into the tissues. Emergency guidance is to call for an airway expert, apply oxygen to face and stoma and assess breathing. Reinsertion is done only by trained staff.
Answer
A · Call for expert help and give oxygen to both the face and the stoma