Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
falls 25, diagnosis 15, aid 15/30, IV 20, gait 10/20, mental status 15
NEWS2 risk
0–4 low; single 3 low–medium; 5–6 medium; ≥ 7 high
Mean arterial pressure
MAP = (SBP + 2·DBP)/3 = DBP + PP/3
Pulse pressure and shock index
PP = SBP − DBP, SI = HR/SBP
Body mass index
BMI = kg/m² = 703·lb/in²
Method
Find the score sheet that the question uses and its range (GCS 3–15, APGAR 0–10, Braden 6–23, Morse 0–125).
Score every item separately, matching the description to its level.
Add the item scores and check that the total lies inside the range.
Apply the cut-offs: for NEWS2 also look for any single parameter scoring 3.
For derived values use MAP = (SBP + 2·DBP)/3, PP = SBP − DBP, SI = HR/SBP and BMI = kg/m².
Med-surg: cardiovascular & respiratory
Method
Name the problem: pump failure, blocked artery, rhythm, clot, airway narrowing, infection or a device problem.
Check the danger signs first: hypoxia, hypotension, chest pain, new confusion, a cold pulseless limb.
Match the oxygen to the patient: 94–98% for most, 88–92% for those at risk of CO₂ retention.
Link each drug to its test and its risk: warfarin and INR, heparin and aPTT and platelets, diuretics and potassium.
Choose the safe first action, then escalate and reassess.
2Practice problems
1.Oxygen therapy & respiratory calculationsMedium
Practice exercise (made-up values, not clinical guidance). A size H oxygen cylinder (factor 3.14 L/psi) reads 1750 psi and runs at 15 L/min. Keeping a safe residual of 200 psi, how many minutes t will it last? Round down to a whole minute.
1750 psif = 3.14 L/psi15 L/min200 psi
t = min
2.Oxygen therapy & respiratory calculationsHard
Practice exercise (made-up values, not clinical guidance). A cylinder with a water capacity of 2 L is filled to 145 bar and runs at 6 L/min. The gas volume is about the water capacity × the pressure. In this exercise the cylinder is changed at 20 bar. How many minutes t until it must be changed? Round down to a whole minute.
2 L145 bar6 L/min20 bar
t = min
3.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.20, PaCO₂ 21 mmHg (2.8 kPa) and HCO₃⁻ 8 mmol/L. The primary disorder is metabolic acidosis. How far is it compensated? Click your answer.
pH 7.20PaCO₂ 21 mmHg (2.8 kPa)HCO₃⁻ 8 mmol/L
1uncompensated
2partially compensated
3fully compensated
4.Arterial blood gas interpretationHard
A practice gas shows a metabolic alkalosis with HCO₃⁻ 38 mmol/L. Use expected PaCO₂ = 0.7·HCO₃⁻ + 21 to find the expected PaCO₂.
HCO₃⁻ 38 mmol/L
PaCO₂ = mmHg
5.Clinical assessment scoresMedium
Practice exercise (made-up values, not clinical guidance). A practice patient is assessed with the Braden scale: sensory perception: slightly limited; moisture: constantly moist; activity: chairfast; mobility: completely immobile; nutrition: excellent; friction and shear: potential problem. Find the Braden total B.
6–23
B =
6.Clinical assessment scoresHard
Practice exercise (made-up values, not clinical guidance). The team aims for a mean arterial pressure of at least 65 mmHg. A patient’s systolic pressure is 125 mmHg. Using MAP = (SBP + 2·DBP)/3, what is the lowest diastolic pressure DBP that still gives a MAP of 65 mmHg?
MAP 65 mmHgSBP 125 mmHg
DBP = mmHg
7.Med-surg: cardiovascular & respiratoryMedium
A patient with peripheral arterial disease has leg pain at night. Which position may ease it?
AApplying a hot water bottle directly to the feet
BHanging the legs down over the side of the bed
CWrapping the legs in compression bandages
DRaising the legs on pillows above heart level
8.Med-surg: cardiovascular & respiratoryHard
A patient being treated for pulmonary TB repeatedly misses doses and stops when they feel better. Which strategy is most effective?
ADoubling the dose on the days the patient remembers to take it
BStopping treatment, as it is clearly not working for this patient
CSwitching to a single drug to make it easier
DDirectly observed therapy with support for barriers to adherence
3Solutions
1.Oxygen therapy & respiratory calculations
Answer: t = 324 min
Cylinder duration: usable litres = (gauge pressure − safe residual) × cylinder factor, with the safe residual usually 200 psi. Cylinder factors in L/psi: D 0.16, E 0.28, H (and K) 3.14. Duration (min) = usable litres/flow (L/min). Round a duration down, never up, so the cylinder is changed in time. In bar-based systems, the gas volume is the water capacity (L) × the pressure (bar).
Usable litres
(1750 − 200)·3.14 = 4867 L
Duration
4867/15 = 324.5 min → t = 324 min
Answer
t = 324 min
That is about 5 h 24 min.
2.Oxygen therapy & respiratory calculations
Answer: t = 41 min
Cylinder duration: usable litres = (gauge pressure − safe residual) × cylinder factor, with the safe residual usually 200 psi. Cylinder factors in L/psi: D 0.16, E 0.28, H (and K) 3.14. Duration (min) = usable litres/flow (L/min). Round a duration down, never up, so the cylinder is changed in time. In bar-based systems, the gas volume is the water capacity (L) × the pressure (bar).
Usable gas
2·(145 − 20) = 250 L
Duration
250/6 = 41.67 min → t = 41 min
Answer
t = 41 min
3.Arterial blood gas interpretation
Answer: partially compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.20: acidaemia (below 7.35)
PaCO₂ 21 mmHg: low (35–45)
HCO₃⁻ 8 mmol/L: low (22–26)
Compensation
partially compensated
Answer
partially compensated
4.Arterial blood gas interpretation
Answer: PaCO₂ = 47.6 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
0.7·38 + 21 = 47.6 mmHg
Answer
PaCO₂ = 47.6 mmHg
The rise has a limit: PaCO₂ rarely goes above about 55 mmHg from compensation alone.
5.Clinical assessment scores
Answer: B = 13
Braden scale: six subscales for pressure-injury risk. Sensory perception, moisture, activity, mobility and nutrition score 1 to 4, from the worst level (1) to no problem (4); friction and shear scores 1 to 3. The total runs from 6 to 23, and a lower total means a higher risk. Common bands: 19–23 not at risk, 15–18 mild risk, 13–14 moderate risk, 10–12 high risk and 9 or below very high risk.
Score each subscale
sensory perception: slightly limited → 3
moisture: constantly moist → 1
activity: chairfast → 2
mobility: completely immobile → 1
nutrition: excellent → 4
friction and shear: potential problem → 2
Add
Braden total = 3 + 1 + 2 + 1 + 4 + 2 = 13
Answer
B = 13
6.Clinical assessment scores
Answer: DBP = 35 mmHg
Blood pressure values: pulse pressure PP = SBP − DBP. Mean arterial pressure MAP ≈ (SBP + 2·DBP)/3 = DBP + PP/3, an estimate based on the heart spending about two thirds of each beat in diastole at a normal heart rate (less accurate when the heart rate is fast); a MAP of at least about 65 mmHg is a common target for organ perfusion. The shock index SI = heart rate/SBP is normally about 0.5–0.7; a value above about 1 is a warning sign of shock.
Rearrange
DBP = (3·MAP − SBP)/2
Substitute
DBP = (3·65 − 125)/2 = 70/2 = 35 mmHg
Answer
DBP = 35 mmHg
7.Med-surg: cardiovascular & respiratory
Answer: B · Hanging the legs down over the side of the bed
Why this is the answer
Ischaemic rest pain is often relieved by lowering the legs, which improves arterial flow by gravity. Elevation worsens ischaemia. Compression is contraindicated in significant arterial disease, and direct heat can burn insensitive, ischaemic skin.
Answer
B · Hanging the legs down over the side of the bed
8.Med-surg: cardiovascular & respiratory
Answer: D · Directly observed therapy with support for barriers to adherence
Why this is the answer
Directly observed therapy, where a health worker watches each dose, plus help with practical and social barriers, improves completion and reduces multidrug-resistant TB. Single-drug therapy or interrupted treatment breeds resistance.
Answer
D · Directly observed therapy with support for barriers to adherence