Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
falls 25, diagnosis 15, aid 15/30, IV 20, gait 10/20, mental status 15
NEWS2 risk
0–4 low; single 3 low–medium; 5–6 medium; ≥ 7 high
Mean arterial pressure
MAP = (SBP + 2·DBP)/3 = DBP + PP/3
Pulse pressure and shock index
PP = SBP − DBP, SI = HR/SBP
Body mass index
BMI = kg/m² = 703·lb/in²
Method
Find the score sheet that the question uses and its range (GCS 3–15, APGAR 0–10, Braden 6–23, Morse 0–125).
Score every item separately, matching the description to its level.
Add the item scores and check that the total lies inside the range.
Apply the cut-offs: for NEWS2 also look for any single parameter scoring 3.
For derived values use MAP = (SBP + 2·DBP)/3, PP = SBP − DBP, SI = HR/SBP and BMI = kg/m².
Med-surg: cardiovascular & respiratory
Method
Name the problem: pump failure, blocked artery, rhythm, clot, airway narrowing, infection or a device problem.
Check the danger signs first: hypoxia, hypotension, chest pain, new confusion, a cold pulseless limb.
Match the oxygen to the patient: 94–98% for most, 88–92% for those at risk of CO₂ retention.
Link each drug to its test and its risk: warfarin and INR, heparin and aPTT and platelets, diuretics and potassium.
Choose the safe first action, then escalate and reassess.
2Practice problems
1.Oxygen therapy & respiratory calculationsMedium
Practice exercise (made-up values, not clinical guidance). A size H oxygen cylinder (factor 3.14 L/psi) reads 1750 psi and runs at 12 L/min. Keeping a safe residual of 200 psi, how many minutes t will it last? Round down to a whole minute.
1750 psif = 3.14 L/psi12 L/min200 psi
t = min
2.Oxygen therapy & respiratory calculationsHard
Practice exercise (made-up values, not clinical guidance). A ventilated woman is 181 cm tall and weighs 122 kg. Lung-protective ventilation is set at 5 mL per kg of predicted body weight. Using PBW = 45.5 + 0.91 × (height cm − 152.4) kg, find the tidal volume VT to the nearest mL.
181 cm122 kg5 mL/kg
VT = mL
3.Arterial blood gas interpretationMedium
A practice gas shows PaCO₂ 77 mmHg (10.3 kPa). Use the rule that in chronic respiratory acidosis HCO₃⁻ rises by 3.5 mmol/L for every 10 mmHg that PaCO₂ is above 40, starting from HCO₃⁻ 24 mmol/L, to find the expected HCO₃⁻.
A practice gas shows a metabolic acidosis: pH 7.22, PaCO₂ 43 mmHg (5.7 kPa), HCO₃⁻ 17 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.22PaCO₂ 43 mmHg (5.7 kPa)HCO₃⁻ 17 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
5.Clinical assessment scoresMedium
Practice exercise (made-up values, not clinical guidance). A practice patient is assessed with the Braden scale: sensory perception: very limited; moisture: occasionally moist; activity: chairfast; mobility: very limited; nutrition: adequate; friction and shear: problem. Find the Braden total B.
6–23
B =
6.Clinical assessment scoresHard
Practice exercise (made-up values, not clinical guidance). An adult weighs 57 kg and is 194 cm tall. Calculate the BMI and click the WHO weight category.
57 kg194 cm
1underweight
2healthy weight
3overweight
4obesity class I
5obesity class II
6obesity class III
7.Med-surg: cardiovascular & respiratoryMedium
Rheumatic heart disease most often follows which infection?
AA group A streptococcal throat infection
BStaphylococcal infection of the skin
CA viral infection of the upper airway
DA fungal infection of the lungs
8.Med-surg: cardiovascular & respiratoryHard
The stump of a recent below-knee amputation suddenly bleeds heavily through the dressing. What should the nurse do first?
AEncourage the patient to walk on crutches to ease the pressure
BRemove all the dressings and wait for the bleeding to stop by itself
CApply a warm compress to the stump
DApply firm direct pressure and call for urgent surgical help
3Solutions
1.Oxygen therapy & respiratory calculations
Answer: t = 405 min
Cylinder duration: usable litres = (gauge pressure − safe residual) × cylinder factor, with the safe residual usually 200 psi. Cylinder factors in L/psi: D 0.16, E 0.28, H (and K) 3.14. Duration (min) = usable litres/flow (L/min). Round a duration down, never up, so the cylinder is changed in time. In bar-based systems, the gas volume is the water capacity (L) × the pressure (bar).
Usable litres
(1750 − 200)·3.14 = 4867 L
Duration
4867/12 = 405.6 min → t = 405 min
Answer
t = 405 min
That is about 6 h 45 min.
2.Oxygen therapy & respiratory calculations
Answer: VT = 358 mL
Ventilation: minute ventilation V̇E = tidal volume × respiratory rate (normal adult about 5–8 L/min). Alveolar ventilation V̇A = (tidal volume − dead space) × rate, because the air in the airways (about 150 mL in an adult) takes no part in gas exchange. Lung-protective ventilation uses about 6 mL per kg of predicted body weight (PBW): men 50 + 0.91 × (height in cm − 152.4) kg, women 45.5 + 0.91 × (height in cm − 152.4) kg (with inches: 2.3 per inch above 60 in).
Predicted body weight
PBW = 45.5 + 0.91·(181 − 152.4) = 71.53 kg
Tidal volume
VT = 5·71.53 = 357.6 ≈ 358 mL
Answer
VT = 358 mL
3.Arterial blood gas interpretation
Answer: HCO₃⁻ = 36.95 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Change in PaCO₂
|77 − 40| = 37 mmHg → 3.7 × 10 mmHg
Expected HCO₃⁻
HCO₃⁻ = 24 + 3.5·3.7 = 36.95 mmol/L
Answer
HCO₃⁻ = 36.95 mmol/L
4.Arterial blood gas interpretation
Answer: added respiratory acidosis
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·17 + 8 = 33.5 → 31.5–35.5 mmHg
Compare
measured: 43 mmHg → added respiratory acidosis
Answer
added respiratory acidosis
5.Clinical assessment scores
Answer: B = 13
Braden scale: six subscales for pressure-injury risk. Sensory perception, moisture, activity, mobility and nutrition score 1 to 4, from the worst level (1) to no problem (4); friction and shear scores 1 to 3. The total runs from 6 to 23, and a lower total means a higher risk. Common bands: 19–23 not at risk, 15–18 mild risk, 13–14 moderate risk, 10–12 high risk and 9 or below very high risk.
Score each subscale
sensory perception: very limited → 2
moisture: occasionally moist → 3
activity: chairfast → 2
mobility: very limited → 2
nutrition: adequate → 3
friction and shear: problem → 1
Add
Braden total = 2 + 3 + 2 + 2 + 3 + 1 = 13
Answer
B = 13
6.Clinical assessment scores
Answer: underweight
Body mass index: BMI = weight (kg)/height (m)², with the height converted to metres first. With pounds and inches, BMI = 703 × weight (lb)/height (in)². WHO adult categories: below 18.5 underweight, 18.5–24.9 healthy weight, 25.0–29.9 overweight, 30.0–34.9 obesity class I, 35.0–39.9 obesity class II and 40 or more obesity class III.
BMI
BMI = 57/1.94² = 15.15
Category
underweight
Answer
underweight
7.Med-surg: cardiovascular & respiratory
Answer: A · A group A streptococcal throat infection
Why this is the answer
Rheumatic fever is an autoimmune reaction weeks after group A streptococcal pharyngitis. It can permanently damage heart valves, most often the mitral valve. Prompt antibiotic treatment of strep throat prevents it.
Answer
A · A group A streptococcal throat infection
8.Med-surg: cardiovascular & respiratory
Answer: D · Apply firm direct pressure and call for urgent surgical help
Why this is the answer
Haemorrhage from a stump needs immediate direct pressure, elevation if appropriate, and urgent surgical help. A tourniquet should be available as policy directs. Vital signs are monitored for shock.
Answer
D · Apply firm direct pressure and call for urgent surgical help