1.Easy
When human muscle cells lack oxygen, pyruvate is converted into:
- AEthanol
- BAcetyl-CoA
- CGlucose
- DLactate
2.Easy
Which molecule brings amino acids to the ribosome during translation?
- ADNA polymerase
- BTransfer RNA (tRNA)
- CMessenger RNA (mRNA)
- DRibosomal RNA (rRNA)
3.Easy
What happens to a red blood cell placed in pure water?
- AIt stays the same size
- BIt swells and may burst
- CIt shrinks and shrivels
- DIt divides into two cells
4.Medium
What are aquaporins?
- AEnzymes that split water into hydrogen and oxygen in membranes
- BChannel proteins that let water cross membranes quickly
- CReceptors for water-soluble hormones
- DPumps that move sodium out of cells
5.Medium
Which cell junction lets ions and small molecules pass directly between neighbouring cells?
- AAdherens junction
- BGap junction
- CTight junction
- DDesmosome
6.Medium
Which cell junction seals neighbouring epithelial cells together and stops fluid leaking between them?
- ATight junction
- BHemidesmosome
- CDesmosome
- DGap junction
7.Hard
In the Meselson–Stahl experiment, bacteria grown in ¹⁵N were moved to ¹⁴N. After one round of replication all DNA formed one band of intermediate density. Which model did this rule out?
- ABoth semi-conservative and dispersive models
- BThe conservative model
- CThe semi-conservative model
- DThe dispersive model
8.Hard
Knudson's "two-hit" hypothesis, based on retinoblastoma, explains that tumour suppressor genes:
- AUsually need both alleles to be inactivated before a tumour develops
- BAre always inherited in mutated form from both the mother and the father
- CCause cancer when one allele is overactive
- DAre only found in children
Answer key
- 1. D · Lactate
- 2. B · Transfer RNA (tRNA)
- 3. B · It swells and may burst
- 4. B · Channel proteins that let water cross membranes quickly
- 5. B · Gap junction
- 6. A · Tight junction
- 7. B · The conservative model
- 8. A · Usually need both alleles to be inactivated before a tumour develops
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