1.Easy
Which part of the cytoskeleton forms the mitotic spindle?
- AActin filaments
- BMicrotubules
- CIntermediate filaments
- DCollagen fibres
2.Easy
What is a mutation?
- AA change in the DNA base sequence
- BThe splitting of a chromosome during mitosis
- CThe normal copying of DNA
- DA change in the shape of the cell
3.Easy
Which base is found in RNA instead of thymine?
- AGuanine
- BCytosine
- CUracil
- DAdenine
4.Medium
What separates during anaphase I of meiosis?
- ASister chromatids
- BCentromeres of each chromatid
- CHomologous chromosomes
- DWhole nuclei
5.Medium
How do large proteins such as transcription factors enter the nucleus?
- AThey are made inside the nucleus by nuclear ribosomes, so they never enter
- BThrough nuclear pore complexes, guided by a nuclear localisation signal
- CBy exocytosis from the endoplasmic reticulum
- DBy diffusing freely through the nuclear membrane lipids
6.Medium
Transcription produces:
- ADNA from DNA
- BmRNA from a DNA template
- CDNA from RNA
- DProtein from mRNA
7.Hard
The endosymbiotic theory is supported by the fact that mitochondria:
- AContain chlorophyll
- BHave no membranes
- CHave their own circular DNA and 70S-like ribosomes
- DAre made in the nucleus
8.Hard
How can one human gene produce several different proteins?
- ABy using a different genetic code in each tissue
- BBy alternative splicing of its pre-mRNA
- CBy copying the gene into different chromosomes
- DBy reading the gene in all three frames at once
Answer key
- 1. B · Microtubules
- 2. A · A change in the DNA base sequence
- 3. C · Uracil
- 4. C · Homologous chromosomes
- 5. B · Through nuclear pore complexes, guided by a nuclear localisation signal
- 6. B · mRNA from a DNA template
- 7. C · Have their own circular DNA and 70S-like ribosomes
- 8. B · By alternative splicing of its pre-mRNA
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