1.Easy
Which base is found in RNA instead of thymine?
- AGuanine
- BCytosine
- CUracil
- DAdenine
2.Easy
What is diffusion?
- AMovement of water only across a membrane
- BNet movement of particles from high to low concentration
- CMovement of particles against their concentration gradient using ATP
- DEngulfing of particles by the cell membrane
3.Easy
What is the main function of lysosomes?
- AProducing ATP by respiration
- BMaking proteins for export and packaging them into secretory vesicles
- CBreaking down worn-out parts and engulfed material with enzymes
- DStoring the cell's DNA
4.Medium
How do large proteins such as transcription factors enter the nucleus?
- AThrough nuclear pore complexes, guided by a nuclear localisation signal
- BBy diffusing freely through the nuclear membrane lipids
- CThey are made inside the nucleus by nuclear ribosomes, so they never enter
- DBy exocytosis from the endoplasmic reticulum
5.Medium
What directly drives ATP synthase to make ATP in mitochondria?
- AProtons flowing back into the matrix down their gradient
- BOxygen diffusing into the matrix
- CGlucose binding to ATP synthase
- DElectrons from NADH flowing directly through ATP synthase
6.Medium
What role does cholesterol play in animal cell membranes?
- AIt forms channels for ions
- BIt helps keep membrane fluidity stable across temperatures
- CIt is the main carrier of glucose
- DIt makes the membrane completely rigid at every temperature
7.Hard
Non-disjunction during meiosis can result in:
- ACrossing over
- BIdentical twins
- CGametes with an abnormal number of chromosomes, such as in Down syndrome
- DMitochondrial DNA mutations only, which are passed on through the egg cytoplasm
8.Hard
Tumour suppressor genes such as p53 normally:
- AMake cells immortal
- BProduce growth factors
- CStop the cell cycle or trigger apoptosis when DNA is damaged
- DSpeed up cell division so that damaged cells are quickly replaced
Answer key
- 1. C · Uracil
- 2. B · Net movement of particles from high to low concentration
- 3. C · Breaking down worn-out parts and engulfed material with enzymes
- 4. A · Through nuclear pore complexes, guided by a nuclear localisation signal
- 5. A · Protons flowing back into the matrix down their gradient
- 6. B · It helps keep membrane fluidity stable across temperatures
- 7. C · Gametes with an abnormal number of chromosomes, such as in Down syndrome
- 8. C · Stop the cell cycle or trigger apoptosis when DNA is damaged
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