1.Easy
The cell membrane is mainly made of:
- AStarch
- BA phospholipid bilayer with proteins
- CDNA
- DCellulose
2.Easy
Which base is found in RNA instead of thymine?
- AAdenine
- BCytosine
- CGuanine
- DUracil
3.Easy
What is cytokinesis?
- AThe division of the cytoplasm into two daughter cells
- BThe breakdown of the nuclear envelope
- CThe pairing of homologous chromosomes
- DThe copying of DNA before division
4.Medium
Cyclin-dependent kinases (CDKs) that drive the cell cycle become active when they bind to:
- AHistones
- BTubulins
- CRibosomes
- DCyclins
5.Medium
How do steroid hormones such as cortisol mainly act on their target cells?
- AThey activate adenylyl cyclase from outside the cell
- BThey bind a membrane receptor and open ion channels, changing the cell's membrane potential
- CThey are taken up by phagocytosis and digested
- DThey cross the membrane and bind intracellular receptors that change gene transcription
6.Medium
A competitive inhibitor binds the active site of an enzyme. What can overcome its effect?
- ARaising the inhibitor concentration
- BLowering the temperature to 0 °C
- CRemoving the enzyme's cofactor
- DRaising the substrate concentration
7.Hard
Knudson's "two-hit" hypothesis, based on retinoblastoma, explains that tumour suppressor genes:
- AAre only found in children
- BCause cancer when one allele is overactive
- CAre always inherited in mutated form from both the mother and the father
- DUsually need both alleles to be inactivated before a tumour develops
8.Hard
Non-disjunction during meiosis can result in:
- AIdentical twins
- BMitochondrial DNA mutations only, which are passed on through the egg cytoplasm
- CCrossing over
- DGametes with an abnormal number of chromosomes, such as in Down syndrome
Answer key
- 1. B · A phospholipid bilayer with proteins
- 2. D · Uracil
- 3. A · The division of the cytoplasm into two daughter cells
- 4. D · Cyclins
- 5. D · They cross the membrane and bind intracellular receptors that change gene transcription
- 6. D · Raising the substrate concentration
- 7. D · Usually need both alleles to be inactivated before a tumour develops
- 8. D · Gametes with an abnormal number of chromosomes, such as in Down syndrome
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