Practice exercise (made-up values, not clinical guidance). A new test was compared with the reference standard in a study (see the 2 × 2 table). Find the negative predictive value NPV as a percentage. Round to one decimal place.
Evidence-based practice statistics worksheet with answers
Practice exercise (made-up values, not clinical guidance). A new test was compared with the reference standard in a study (see the 2 × 2 table). Find the specificity Sp as a percentage. Round to one decimal place.
Practice exercise (made-up values, not clinical guidance). A case-control study compares 250 patients with a disease (cases) and 310 people without it (controls). The table shows how many in each group were exposed to a risk factor. Find the odds ratio OR for the exposure. Round to two decimal places.
Practice exercise (made-up values, not clinical guidance). In a cohort, groups of people were followed for different lengths of time (see the table: number of people and years of follow-up for each). During follow-up, 119 new cases occurred. Find the incidence rate IR per 1000 person-years. Round to one decimal place.
Practice exercise (made-up values, not clinical guidance). A patient has a pre-test probability of 60% for a disease. A test with sensitivity 89% and specificity 90% comes back negative. Find the post-test probability p′ of the disease as a percentage. Round to one decimal place.
Practice exercise (made-up values, not clinical guidance). 10 000 people are screened with a test of sensitivity 96% and specificity 78%. The prevalence of the disease is 12%. How many true-positive results TP are expected?
Answer key
- 1. NPV = 89 %
- 2. Sp = 65 %
- 3. OR = 0.4
- 4. IR = 43.3 per 1000 person-years
- 5. p′ = 15.5 %
- 6. TP = 1152
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