Practice exercise (made-up values, not clinical guidance). A new test was compared with the reference standard in a study (see the 2 × 2 table). Find the positive predictive value PPV as a percentage. Round to one decimal place.
Evidence-based practice statistics worksheet with answers
Practice exercise (made-up values, not clinical guidance). A town has 30 000 inhabitants. At the start of a year, 699 of them have a chronic disease. During the year, 163 more people are newly diagnosed (assume nobody moves away or dies). Find the cumulative incidence CI over the year per 1000 people at risk. Round to one decimal place.
Practice exercise (made-up values, not clinical guidance). A case-control study compares 210 patients with a disease (cases) and 740 people without it (controls). The table shows how many in each group were exposed to a risk factor. Find the odds ratio OR for the exposure. Round to two decimal places.
Practice exercise (made-up values, not clinical guidance). In a cohort, groups of people were followed for different lengths of time (see the table: number of people and years of follow-up for each). During follow-up, 71 new cases occurred. Find the incidence rate IR per 1000 person-years. Round to one decimal place.
Practice exercise (made-up values, not clinical guidance). A patient has a pre-test probability of 60% for a disease. A test with sensitivity 78% and specificity 61% comes back positive. Find the post-test probability p′ of the disease as a percentage. Round to one decimal place.
Practice exercise (made-up values, not clinical guidance). A screening test has a sensitivity of 75% and a specificity of 81%. It is used in a population where the prevalence is 2%. Find the positive predictive value PPV as a percentage. Round to one decimal place.
Answer key
- 1. PPV = 79.7 %
- 2. CI = 5.6 per 1000
- 3. OR = 0.4
- 4. IR = 43.3 per 1000 person-years
- 5. p′ = 75 %
- 6. PPV = 7.5 %
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