Evidence-based practice statistics worksheet with answers

Free printable Evidence-based practice statistics worksheet: 6 problems from easy to exam level, with an answer key. Print it or save it as a PDF.

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Name: ____________________   Date: ____________

1.Easy
testdisease presentdisease absenttotalpositive134297431abnegative86763849cdtotal22010601280

Practice exercise (made-up values, not clinical guidance). A new test was compared with the reference standard in a study (see the 2 × 2 table). Find the specificity Sp as a percentage. Round to one decimal place.

a = 134b = 297c = 86d = 763
Sp = %
2.Easy
testdisease presentdisease absenttotalpositive193503696abnegative879771064cdtotal28014801760

Practice exercise (made-up values, not clinical guidance). A new test was compared with the reference standard in a study (see the 2 × 2 table). Find the positive predictive value PPV as a percentage. Round to one decimal place.

a = 193b = 503c = 87d = 977
PPV = %
3.Medium
eventno eventtotaltreatment71349420abcontrol176454630cd

Practice exercise (made-up values, not clinical guidance). In a randomised trial, 420 patients received a new treatment and 630 received the control treatment. The table shows how many in each group had the outcome (an unwanted event such as a stroke). Find the number needed to treat NNT to prevent one event. Round up to a whole number of patients.

treatment: 71/420control: 176/630
NNT =
4.Medium
Se83%Sp80%LR+ = ?

Practice exercise (made-up values, not clinical guidance). A test has a sensitivity of 83% and a specificity of 80%. Find the positive likelihood ratio LR+. Round to two decimal places.

Se = 83%Sp = 80%
LR+ =
5.Hard
control25%treatment?

Practice exercise (made-up values, not clinical guidance). Without a drug, 25% of patients have a certain side effect during a year. The drug raises this risk with a relative risk of RR = 1.91. Find the number needed to harm NNH: how many patients must take the drug for a year for one extra patient to have the side effect? Round up to a whole number of patients.

control 25%RR = 1.91
NNH =
6.Hard
testdisease presentdisease absenttotalpositivenegative?total10 000

Practice exercise (made-up values, not clinical guidance). 10 000 people are screened with a test of sensitivity 92% and specificity 76%. The prevalence of the disease is 13%. How many people with the disease are missed by the test (false negatives, FN)?

N = 10 000p = 13%Se = 92%Sp = 76%
FN =

Answer key

  1. 1. Sp = 72 %
  2. 2. PPV = 27.7 %
  3. 3. NNT = 10
  4. 4. LR+ = 4.15
  5. 5. NNH = 5
  6. 6. FN = 104

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