Practice exercise (made-up values, not clinical guidance). A new test was compared with the reference standard in a study (see the 2 × 2 table). Find the specificity Sp as a percentage. Round to one decimal place.
Evidence-based practice statistics worksheet with answers
Practice exercise (made-up values, not clinical guidance). A town has 9500 inhabitants. At the start of a year, 53 of them have a chronic disease. During the year, 84 more people are newly diagnosed (assume nobody moves away or dies). Find the point prevalence P at the start of the year per 1000 inhabitants. Round to one decimal place.
Practice exercise (made-up values, not clinical guidance). In a randomised trial, 980 patients received a new treatment and 680 received the control treatment. The table shows how many in each group had the outcome (an unwanted event such as a stroke). Find the relative risk RR of the event with treatment. Round to two decimal places.
Practice exercise (made-up values, not clinical guidance). In a cohort, groups of people were followed for different lengths of time (see the table: number of people and years of follow-up for each). During follow-up, 163 new cases occurred. Find the incidence rate IR per 1000 person-years. Round to one decimal place.
Practice exercise (made-up values, not clinical guidance). A treatment reduces the risk of an event by 36% in relative terms (RRR = 36%). In a patient group the risk without treatment (CER) is 11% over five years. Find the number needed to treat NNT for five years to prevent one event. Round up to a whole number of patients.
Practice exercise (made-up values, not clinical guidance). A screening test has a sensitivity of 90% and a specificity of 90%. It is used in a population where the prevalence is 1%. Find the positive predictive value PPV as a percentage. Round to one decimal place.
Answer key
- 1. Sp = 64 %
- 2. P = 5.6 per 1000
- 3. RR = 0.71
- 4. IR = 49.7 per 1000 person-years
- 5. NNT = 26
- 6. PPV = 8.3 %
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