Evidence-based practice statistics worksheet with answers

Free printable Evidence-based practice statistics worksheet: 6 problems from easy to exam level, with an answer key. Print it or save it as a PDF.

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Name: ____________________   Date: ____________

1.Easy
testdisease presentdisease absenttotalpositive306280586abnegative5415901644cdtotal36018702230

Practice exercise (made-up values, not clinical guidance). A new test was compared with the reference standard in a study (see the 2 × 2 table). Find the specificity Sp as a percentage. Round to one decimal place.

a = 306b = 280c = 54d = 1590
Sp = %
2.Easy
testdisease presentdisease absenttotalpositive352136488abnegative18204222cdtotal370340710

Practice exercise (made-up values, not clinical guidance). A new test was compared with the reference standard in a study (see the 2 × 2 table). Find the sensitivity Se as a percentage. Round to one decimal place.

a = 352b = 136c = 18d = 204
Se = %
3.Medium
Se84%Sp97%LR− = ?

Practice exercise (made-up values, not clinical guidance). A test has a sensitivity of 84% and a specificity of 97%. Find the negative likelihood ratio LR−. Round to two decimal places.

Se = 84%Sp = 97%
LR− =
4.Medium
eventno eventtotaltreatment101319420abcontrol115845960cd

Practice exercise (made-up values, not clinical guidance). In a randomised trial, 420 patients received a new treatment and 960 received the control treatment. The table shows how many in each group had a side effect. Find the number needed to harm NNH: how many patients must be treated for one extra patient to have the side effect? Round up to a whole number of patients.

treatment: 101/420control: 115/960
NNH =
5.Hard
pre-test15%post-test?p′LR−

Practice exercise (made-up values, not clinical guidance). A patient has a pre-test probability of 15% for a disease. A test with sensitivity 97% and specificity 81% comes back negative. Find the post-test probability p′ of the disease as a percentage. Round to one decimal place.

pre-test 15%Se = 97%Sp = 81%negative
p′ = %
6.Hard
testdisease presentdisease absenttotalpositive?negativetotal10 000

Practice exercise (made-up values, not clinical guidance). 10 000 people are screened with a test of sensitivity 86% and specificity 81%. The prevalence of the disease is 2%. How many true-positive results TP are expected?

N = 10 000p = 2%Se = 86%Sp = 81%
TP =

Answer key

  1. 1. Sp = 85 %
  2. 2. Se = 95.1 %
  3. 3. LR− = 0.16
  4. 4. NNH = 9
  5. 5. p′ = 0.6 %
  6. 6. TP = 172

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