Practice exercise (made-up values, not clinical guidance). A new test was compared with the reference standard in a study (see the 2 × 2 table). Find the negative predictive value NPV as a percentage. Round to one decimal place.
Evidence-based practice statistics worksheet with answers
Practice exercise (made-up values, not clinical guidance). A new test was compared with the reference standard in a study (see the 2 × 2 table). Find the sensitivity Se as a percentage. Round to one decimal place.
Practice exercise (made-up values, not clinical guidance). In a randomised trial, 650 patients received a new treatment and 870 received the control treatment. The table shows how many in each group had the outcome (an unwanted event such as a stroke). Find the relative risk RR of the event with treatment. Round to two decimal places.
Practice exercise (made-up values, not clinical guidance). In a cohort study, exposed people contributed 2100 person-years with 118 new cases, and unexposed people 5100 person-years with 71 new cases. Find the incidence rate ratio IRR (exposed versus unexposed). Round to two decimal places.
Practice exercise (made-up values, not clinical guidance). A treatment reduces the risk of an event by 10% in relative terms (RRR = 10%). In a patient group the risk without treatment (CER) is 9% over five years. Find the number needed to treat NNT for five years to prevent one event. Round up to a whole number of patients.
Practice exercise (made-up values, not clinical guidance). A patient has a pre-test probability of 25% for a disease. A test with sensitivity 66% and specificity 74% comes back positive. Find the post-test probability p′ of the disease as a percentage. Round to one decimal place.
Answer key
- 1. NPV = 87.5 %
- 2. Se = 62.2 %
- 3. RR = 0.4
- 4. IRR = 4.04
- 5. NNT = 112
- 6. p′ = 45.8 %
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