Evidence-based practice statistics worksheet with answers

Free printable Evidence-based practice statistics worksheet: 6 problems from easy to exam level, with an answer key. Print it or save it as a PDF.

For teachers: free to print, copy and use in class. Every new worksheet has new values and its own answer key. A link to ExamProblems on your course page is appreciated.

Name: ____________________   Date: ____________

1.Easy
testdisease presentdisease absenttotalpositive8780167abnegative43300343cdtotal130380510

Practice exercise (made-up values, not clinical guidance). A new test was compared with the reference standard in a study (see the 2 × 2 table). Find the negative predictive value NPV as a percentage. Round to one decimal place.

a = 87b = 80c = 43d = 300
NPV = %
2.Easy
testdisease presentdisease absenttotalpositive14342185abnegative87218305cdtotal230260490

Practice exercise (made-up values, not clinical guidance). A new test was compared with the reference standard in a study (see the 2 × 2 table). Find the sensitivity Se as a percentage. Round to one decimal place.

a = 143b = 42c = 87d = 218
Se = %
3.Medium
eventno eventtotaltreatment104546650abcontrol348522870cd

Practice exercise (made-up values, not clinical guidance). In a randomised trial, 650 patients received a new treatment and 870 received the control treatment. The table shows how many in each group had the outcome (an unwanted event such as a stroke). Find the relative risk RR of the event with treatment. Round to two decimal places.

treatment: 104/650control: 348/870
RR =
4.Medium
casesperson-yearsexposed1182100not exposed715100

Practice exercise (made-up values, not clinical guidance). In a cohort study, exposed people contributed 2100 person-years with 118 new cases, and unexposed people 5100 person-years with 71 new cases. Find the incidence rate ratio IRR (exposed versus unexposed). Round to two decimal places.

exposed: 118/2100 PYnot exposed: 71/5100 PY
IRR =
5.Hard
CER9%EER?RRR 10%

Practice exercise (made-up values, not clinical guidance). A treatment reduces the risk of an event by 10% in relative terms (RRR = 10%). In a patient group the risk without treatment (CER) is 9% over five years. Find the number needed to treat NNT for five years to prevent one event. Round up to a whole number of patients.

RRR = 10%CER = 9%
NNT =
6.Hard
pre-test25%post-test?p′LR+

Practice exercise (made-up values, not clinical guidance). A patient has a pre-test probability of 25% for a disease. A test with sensitivity 66% and specificity 74% comes back positive. Find the post-test probability p′ of the disease as a percentage. Round to one decimal place.

pre-test 25%Se = 66%Sp = 74%positive
p′ = %

Answer key

  1. 1. NPV = 87.5 %
  2. 2. Se = 62.2 %
  3. 3. RR = 0.4
  4. 4. IRR = 4.04
  5. 5. NNT = 112
  6. 6. p′ = 45.8 %

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