Evidence-based practice statistics worksheet with answers

Free printable Evidence-based practice statistics worksheet: 6 problems from easy to exam level, with an answer key. Print it or save it as a PDF.

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Name: ____________________   Date: ____________

1.Easy
01 yearN = 14 000cases: 312new cases: 135CI = ?

Practice exercise (made-up values, not clinical guidance). A town has 14 000 inhabitants. At the start of a year, 312 of them have a chronic disease. During the year, 135 more people are newly diagnosed (assume nobody moves away or dies). Find the cumulative incidence CI over the year per 1000 people at risk. Round to one decimal place.

N = 14 000existing cases = 312new cases = 135
CI = per 1000
2.Easy
testdisease presentdisease absenttotalpositive318418736abnegative5215721624cdtotal37019902360

Practice exercise (made-up values, not clinical guidance). A new test was compared with the reference standard in a study (see the 2 × 2 table). Find the negative predictive value NPV as a percentage. Round to one decimal place.

a = 318b = 418c = 52d = 1572
NPV = %
3.Medium
Se90%Sp86%LR− = ?

Practice exercise (made-up values, not clinical guidance). A test has a sensitivity of 90% and a specificity of 86%. Find the negative likelihood ratio LR−. Round to two decimal places.

Se = 90%Sp = 86%
LR− =
4.Medium
peopleyears160022500335701.5new cases146

Practice exercise (made-up values, not clinical guidance). In a cohort, groups of people were followed for different lengths of time (see the table: number of people and years of follow-up for each). During follow-up, 146 new cases occurred. Find the incidence rate IR per 1000 person-years. Round to one decimal place.

600 × 2 years500 × 3 years570 × 1.5 years146 new cases
IR = per 1000 person-years
5.Hard
pre-test20%post-test?p′LR−

Practice exercise (made-up values, not clinical guidance). A patient has a pre-test probability of 20% for a disease. A test with sensitivity 83% and specificity 81% comes back negative. Find the post-test probability p′ of the disease as a percentage. Round to one decimal place.

pre-test 20%Se = 83%Sp = 81%negative
p′ = %
6.Hard
testdisease presentdisease absenttotalpositive?negativetotal10 000

Practice exercise (made-up values, not clinical guidance). 10 000 people are screened with a test of sensitivity 74% and specificity 77%. The prevalence of the disease is 5%. How many true-positive results TP are expected?

N = 10 000p = 5%Se = 74%Sp = 77%
TP =

Answer key

  1. 1. CI = 9.9 per 1000
  2. 2. NPV = 96.8 %
  3. 3. LR− = 0.12
  4. 4. IR = 41.1 per 1000 person-years
  5. 5. p′ = 5 %
  6. 6. TP = 370

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