1.Easy
Why is serum creatinine a better marker of kidney function than BUN?
- AIt is made by the liver, so it rises in every kind of illness
- BIt is less affected by diet, hydration and bleeding in the gut
- CIt is not filtered by the kidneys, so its level stays very stable
- DIt is affected mainly by protein intake, which is easy to control
2.Easy
What does the specificity of a diagnostic test describe?
- AThe cost of the test compared with other tests
- BThe total number of people who take the test each year
- CThe proportion of people with the disease who test positive
- DThe proportion of people without the disease who test negative
3.Easy
A laboratory flags a result as high using its own reference range, but the value is inside the range in your textbook. Which range should you use for this patient?
- AThe widest range that you can find in any source
- BThe reference range of the laboratory that ran the test
- CThe textbook range, because textbooks are the national standard
- DThe range used at the hospital where you trained
4.Medium
A patient had a right mastectomy with removal of axillary lymph nodes. Where is the best place to draw blood?
- AThe right arm
- BEither arm equally
- CThe left arm
- DThe right hand
5.Medium
Why is a baseline platelet count taken before starting heparin therapy?
- ABecause heparin increases the platelet count to dangerous levels
- BSo that the INR can be calculated from the platelet count later
- CBecause heparin is given at a dose based on the platelet count
- DSo a later fall from heparin-induced thrombocytopenia is detected
6.Medium
A patient takes valproate (valproic acid) for epilepsy. Which tests are monitored regularly?
- AThyroid function and serum calcium
- BTroponin and B-type natriuretic peptide
- CSerum lithium and urine specific gravity
- DLiver function tests and platelet count
7.Hard
A patient's creatinine was 0.9 mg/dL (80 µmol/L) on admission and is 1.3 mg/dL (115 µmol/L) 36 hours later. Using the common KDIGO criteria, what does this show?
- ANo kidney injury, because the creatinine is still within the normal range
- BChronic kidney disease, because creatinine has risen above baseline
- CA laboratory error, because creatinine cannot change within 2 days
- DAcute kidney injury, because it rose by at least 0.3 mg/dL within 48 hours
8.Hard
A young man has a swollen knee after minor trauma. His aPTT is prolonged, but his PT/INR and platelet count are normal. Which condition fits best?
- AImmune thrombocytopenia (ITP)
- BHemophilia A (factor VIII deficiency)
- CVitamin K deficiency from poor diet
- DDisseminated intravascular coagulation
Answer key
- 1. B · It is less affected by diet, hydration and bleeding in the gut
- 2. D · The proportion of people without the disease who test negative
- 3. B · The reference range of the laboratory that ran the test
- 4. C · The left arm
- 5. D · So a later fall from heparin-induced thrombocytopenia is detected
- 6. D · Liver function tests and platelet count
- 7. D · Acute kidney injury, because it rose by at least 0.3 mg/dL within 48 hours
- 8. B · Hemophilia A (factor VIII deficiency)
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