1.Easy
Lactate is mainly produced when cells:
- ABreak down fat completely with oxygen
- BBreak down protein in the liver for energy
- CStore glucose as glycogen in the muscles
- DBreak down glucose without enough oxygen
2.Easy
What does the specificity of a diagnostic test describe?
- AThe proportion of people without the disease who test negative
- BThe total number of people who take the test each year
- CThe cost of the test compared with other tests
- DThe proportion of people with the disease who test positive
3.Easy
Which blood test is usually the first test used to screen thyroid function?
- AThyroid-stimulating hormone (TSH)
- BHemoglobin A1c (HbA1c)
- CSerum calcium
- DSerum cortisol
4.Medium
A patient with hepatic encephalopathy is receiving lactulose. Which finding best shows that the treatment is effective?
- ASix to eight watery stools a day with dizziness
- BTwo to three soft stools a day and clearer thinking
- CNo bowel movement for 2 days and calm sleep
- DA rising serum ammonia with a slower flapping tremor
5.Medium
Why do patients with chronic kidney disease often have anemia?
- AHigh potassium in kidney disease breaks down red cells
- BThe damaged kidneys filter out and destroy red blood cells
- CUremic toxins make the bone marrow produce white cells instead of red cells
- DThe kidneys make less erythropoietin, which drives red cell production
6.Medium
A patient with iron-deficiency anemia started oral iron. Which result is usually the earliest sign that treatment is working?
- AA fall in the mean cell volume (MCV)
- BA rise in the reticulocyte count
- CA rise in the platelet count
- DA fall in the white cell count
7.Hard
A patient on a heparin infusion has a platelet count that falls from 260 to 110 × 10³/µL on day 7. Which action is most appropriate?
- AContinue the infusion and increase the rate as per protocol
- BTake no action, because the count is still just above 100 × 10³/µL
- CReport it at once: heparin-induced thrombocytopenia is possible
- DGive a platelet transfusion and continue the heparin
8.Hard
A patient with heart failure takes lisinopril, spironolactone and a potassium supplement. Today the potassium is 6.0 mEq/L. What is the most likely explanation?
- APotassium supplements have no effect on the serum level
- BSpironolactone causes potassium loss
- CLisinopril lowers potassium
- DSeveral medicines that raise potassium are being taken together
Answer key
- 1. D · Break down glucose without enough oxygen
- 2. A · The proportion of people without the disease who test negative
- 3. A · Thyroid-stimulating hormone (TSH)
- 4. B · Two to three soft stools a day and clearer thinking
- 5. D · The kidneys make less erythropoietin, which drives red cell production
- 6. B · A rise in the reticulocyte count
- 7. C · Report it at once: heparin-induced thrombocytopenia is possible
- 8. D · Several medicines that raise potassium are being taken together
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