1.Easy
What is a typical reference range for serum osmolality?
- AAbout 400–500 mOsm/kg
- BAbout 135–145 mOsm/kg
- CAbout 275–295 mOsm/kg
- DAbout 50–100 mOsm/kg
2.Easy
Below about which blood glucose level is hypoglycemia usually defined and treated in a person with diabetes?
- A100 mg/dL (5.6 mmol/L)
- B70 mg/dL (3.9 mmol/L)
- C126 mg/dL (7.0 mmol/L)
- D40 mg/dL (2.2 mmol/L)
3.Easy
Using American Diabetes Association (ADA) criteria, a fasting plasma glucose of 100–125 mg/dL (5.6–6.9 mmol/L) is classed as:
- AType 1 diabetes mellitus
- BNormal fasting glucose for an adult
- CMild hypoglycemia (low glucose)
- DPrediabetes (impaired fasting glucose)
4.Medium
A patient's potassium is unexpectedly 5.8 mEq/L. The sample was taken after the tourniquet was on for several minutes while the patient pumped their fist. What is the best interpretation?
- AFist pumping lowers potassium, so the true level is even higher
- BTourniquet time affects only the glucose result, not the potassium
- CThe result confirms true hyperkalemia and needs no further checking
- DThe result may be falsely high and should be repeated with better technique
5.Medium
A patient who is breathless during a transfusion has hypotension, fever and bilateral lung infiltrates, with no signs of fluid overload. Which complication is most likely?
- ATransfusion-related acute lung injury (TRALI)
- BTransfusion-associated circulatory overload
- CA mild febrile nonhemolytic reaction
- DA simple allergic reaction with hives
6.Medium
A patient with type 1 diabetes has the flu, is eating little and has a glucose of 290 mg/dL (16.1 mmol/L). Which advice is correct?
- AKeep taking insulin and check blood or urine ketones
- BWait 3 days before checking the glucose again
- CDrink only water and avoid all carbohydrate foods
- DStop all insulin until you are eating normally again
7.Hard
A patient on warfarin with a stable INR of 2.4 starts a course of an antibiotic such as ciprofloxacin. A week later the INR is 4.6. What is the most likely explanation?
- AA drug interaction that increases the effect of warfarin
- BThe patient has eaten more vitamin K–rich food
- CA laboratory error is the only possible explanation
- DThe antibiotic has cured the patient’s need for anticoagulation
8.Hard
A patient started methimazole for hyperthyroidism 6 weeks ago and now has a fever and a severe sore throat. Which action is most important?
- AGive the next dose and suggest warm salt-water gargles for comfort
- BHold the drug and arrange an urgent white cell and neutrophil count
- CAdvise the patient to continue the drug and drink more fluid
- DCheck the TSH and double the dose if it is still low
Answer key
- 1. C · About 275–295 mOsm/kg
- 2. B · 70 mg/dL (3.9 mmol/L)
- 3. D · Prediabetes (impaired fasting glucose)
- 4. D · The result may be falsely high and should be repeated with better technique
- 5. A · Transfusion-related acute lung injury (TRALI)
- 6. A · Keep taking insulin and check blood or urine ketones
- 7. A · A drug interaction that increases the effect of warfarin
- 8. B · Hold the drug and arrange an urgent white cell and neutrophil count
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