1.Easy
A patient on warfarin asks what an INR of 2.0 means. Which explanation is best?
- AYour blood takes about twice as long as normal to clot
- BYou have twice the normal number of platelets
- CYour warfarin dose is twice what it should be
- DYour blood clots about twice as fast as is normal
2.Easy
A laboratory reports that a blood sample is "hemolyzed." What does this mean?
- ARed cells in the sample have broken open
- BThe sample contains too many platelets
- CThe sample has a very low hemoglobin
- DThe sample was taken from an artery
3.Easy
Which liver test is especially sensitive to heavy alcohol use?
- ASerum creatinine and BUN
- BGamma-glutamyl transferase (GGT)
- CSerum lipase (pancreatic enzyme)
- DCardiac troponin I or T
4.Medium
A test has very high sensitivity for a disease. What does a negative result mean?
- AThe result cannot be used, because sensitivity is high
- BThe patient must have a different disease instead
- CThe disease is certain, so treatment should begin
- DThe disease is unlikely, so it helps rule it out
5.Medium
A breathless patient in the emergency department has a BNP below 100 pg/mL. What does this suggest?
- ASevere heart failure is certainly the cause of the problem
- BThe patient has had a myocardial infarction in the past day
- CHeart failure is an unlikely cause of the breathlessness
- DThe kidneys are failing and the patient needs dialysis
6.Medium
A patient with schizophrenia is starting clozapine. Which laboratory value must be monitored regularly?
- AAbsolute neutrophil count
- BSerum lithium level
- CInternational normalized ratio
- DSerum amylase
7.Hard
A patient with a round face, central weight gain and purple stretch marks has a glucose of 210 mg/dL (11.7 mmol/L) and a potassium of 3.1 mEq/L. Which condition fits best?
- ACushing syndrome
- BHypothyroidism
- CDiabetes insipidus
- DAdrenal insufficiency
8.Hard
A patient with acute pancreatitis has a rising BUN, a falling calcium and a glucose of 250 mg/dL (13.9 mmol/L) over the first 48 hours. What do these results suggest?
- AAn unrelated new kidney stone
- BIncreasingly severe pancreatitis
- CA resolving, mild pancreatitis
- DA lab error from lipemic samples
Answer key
- 1. A · Your blood takes about twice as long as normal to clot
- 2. A · Red cells in the sample have broken open
- 3. B · Gamma-glutamyl transferase (GGT)
- 4. D · The disease is unlikely, so it helps rule it out
- 5. C · Heart failure is an unlikely cause of the breathlessness
- 6. A · Absolute neutrophil count
- 7. A · Cushing syndrome
- 8. B · Increasingly severe pancreatitis
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