1.Easy
Which group of symptoms is typical of hypothyroidism?
- AGreat thirst and passing large volumes of urine
- BHeat intolerance, weight loss, a fine tremor and palpitations
- CCold intolerance, tiredness, weight gain and constipation
- DDiarrhoea, anxiety, sweating and bulging eyes
2.Easy
How do sulfonylureas such as gliclazide lower blood glucose?
- AThey make the pancreas release more insulin
- BThey make the kidneys pass more glucose
- CThey replace insulin that the body lacks
- DThey slow down the absorption of food
3.Easy
Why do many patients with chronic kidney disease develop anaemia?
- AThe kidneys make less erythropoietin
- BThe kidneys break down red blood cells
- CBlood is lost in the urine every day
- DDialysis removes iron from the blood
4.Medium
A patient with migraine takes painkillers or triptans on most days and now has a headache almost every day. What is the likely problem?
- AA brain tumour, which is almost certain
- BAn allergy to the painkillers
- CNormal progress of migraine
- DMedication overuse headache
5.Medium
The day after a thyroidectomy, a patient reports tingling around the mouth and in the fingers. Why might this happen?
- AThe anaesthetic has caused an allergic reaction
- BThe parathyroid glands may have been damaged, lowering calcium
- CThe patient is breathing too slowly after the operation
- DThe thyroid hormone level has risen too high after surgery
6.Medium
A patient's potassium stays low despite replacement. Which other level should be checked?
- AAmylase
- BMagnesium
- CFerritin
- DBilirubin
7.Hard
A patient with a brain tumour on high-dose dexamethasone has a capillary glucose of 16 mmol/L (288 mg/dL). They have no history of diabetes. What is the best explanation?
- ANormal for this patient, so no action is needed
- BA sign that the brain tumour has now spread to the pancreas
- CA lab error, because steroids lower blood glucose
- DSteroid-induced hyperglycaemia, which needs monitoring and treatment
8.Hard
A patient with type 1 diabetes is nil by mouth before surgery tomorrow. Which plan is safest?
- AGive the usual meal-time insulin, even though no meals will be eaten
- BContinue some insulin (basal or a variable-rate IV infusion) with glucose checks
- CStop all insulin until the patient is eating and drinking normally again
- DGive insulin only if the urine ketones become strongly positive overnight
Answer key
- 1. C · Cold intolerance, tiredness, weight gain and constipation
- 2. A · They make the pancreas release more insulin
- 3. A · The kidneys make less erythropoietin
- 4. D · Medication overuse headache
- 5. B · The parathyroid glands may have been damaged, lowering calcium
- 6. B · Magnesium
- 7. D · Steroid-induced hyperglycaemia, which needs monitoring and treatment
- 8. B · Continue some insulin (basal or a variable-rate IV infusion) with glucose checks
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