1.Easy
Why are viruses called obligate intracellular parasites?
- AThey can only replicate inside a living host cell
- BThey only live inside the intestine
- CThey always kill the host cell immediately
- DThey can only be seen inside a cell under a microscope
2.Easy
What is agar used for in a microbiology laboratory?
- ATo stain bacteria purple
- BTo kill bacteria on surfaces
- CTo make culture media solid
- DTo dissolve bacterial cell walls
3.Easy
Which is part of the body's first line of defence against infection?
- AIntact skin
- BCytotoxic T cells
- CMemory B cells
- DAntibodies
4.Medium
What is endotoxin?
- AA toxin produced only inside human cells
- BA protein toxin secreted by Gram-positive bacteria into the surrounding tissue
- CThe lipopolysaccharide in the outer membrane of Gram-negative bacteria
- DA toxin made by fungi in damp buildings
5.Medium
In the lysogenic cycle of a bacteriophage, what happens to the phage DNA?
- AIt is integrated into the bacterial chromosome as a prophage
- BIt is immediately used to make new phages that burst the cell
- CIt is destroyed by the bacterium
- DIt leaves the cell through the pilus
6.Medium
Which vaccine contains live attenuated (weakened) viruses?
- AHepatitis B vaccine
- BTetanus vaccine
- CMMR (measles, mumps, rubella)
- DInactivated influenza injection
7.Hard
After eating home-canned vegetables, a patient develops double vision, difficulty swallowing and a descending flaccid paralysis. What is the most likely cause?
- AA viral infection of the motor neurons
- BEndotoxin from Gram-negative bacteria
- CBotulinum toxin, which blocks acetylcholine release
- DTetanus toxin, which blocks inhibitory neurotransmitters
8.Hard
A healthcare worker's blood test is positive for anti-HBs (hepatitis B surface antibody) and negative for HBsAg and anti-HBc. What does this most likely mean?
- APast natural infection that has cleared
- BCurrent acute hepatitis B infection
- CImmunity from hepatitis B vaccination
- DChronic hepatitis B infection
Answer key
- 1. A · They can only replicate inside a living host cell
- 2. C · To make culture media solid
- 3. A · Intact skin
- 4. C · The lipopolysaccharide in the outer membrane of Gram-negative bacteria
- 5. A · It is integrated into the bacterial chromosome as a prophage
- 6. C · MMR (measles, mumps, rubella)
- 7. C · Botulinum toxin, which blocks acetylcholine release
- 8. C · Immunity from hepatitis B vaccination
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