1.Easy
The HPV vaccine mainly protects against:
- AHIV infection
- BHepatitis B and liver cancer
- CCervical and other cancers caused by human papillomavirus
- DHerpes simplex infection
2.Easy
Lyme disease is transmitted to humans by:
- ACoughing and sneezing
- BTick bites
- CContaminated water
- DMosquito bites
3.Easy
What is the most effective single measure to prevent the spread of infection in hospitals?
- AHand hygiene
- BWearing a face mask at all times
- CGiving every patient antibiotics
- DKeeping windows closed
4.Medium
MRSA is resistant to methicillin because it has:
- AA polysaccharide capsule that blocks the entry of all beta-lactams
- BAn altered penicillin-binding protein (PBP2a)
- CAn efflux pump for every antibiotic
- DNo cell wall at all
5.Medium
In the lysogenic cycle of a bacteriophage, what happens to the phage DNA?
- AIt is immediately used to make new phages that burst the cell
- BIt is integrated into the bacterial chromosome as a prophage
- CIt is destroyed by the bacterium
- DIt leaves the cell through the pilus
6.Medium
Toxoplasma gondii is a risk in pregnancy. Which advice reduces exposure?
- AAvoid cleaning cat litter and avoid undercooked meat
- BAvoid contact with dogs
- CAvoid swimming pools and all other public bathing areas
- DAvoid all fruit and vegetables
7.Hard
A child develops bloody diarrhoea after eating an undercooked burger, then a week later has kidney failure, anaemia and a low platelet count. Which organism is most likely?
- ARotavirus
- BClostridium perfringens
- CShiga toxin-producing E. coli such as O157:H7
- DStaphylococcus aureus
8.Hard
Why must a negative-sense RNA virus such as influenza carry its own RNA-dependent RNA polymerase into the host cell?
- AHost ribosomes cannot read any viral genes
- BThe polymerase protects the virus from antibodies
- CHost cells cannot make mRNA from an RNA template
- DThe polymerase is needed to integrate the genome into host DNA
Answer key
- 1. C · Cervical and other cancers caused by human papillomavirus
- 2. B · Tick bites
- 3. A · Hand hygiene
- 4. B · An altered penicillin-binding protein (PBP2a)
- 5. B · It is integrated into the bacterial chromosome as a prophage
- 6. A · Avoid cleaning cat litter and avoid undercooked meat
- 7. C · Shiga toxin-producing E. coli such as O157:H7
- 8. C · Host cells cannot make mRNA from an RNA template
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