Pharmacology worksheet with answers

How is pernicious anaemia usually treated?

1. AWith folic acid alone
2. BWith blood transfusions every month
3. CWith vitamin B12 injections, usually for life
4. DWith oral iron tablets for three months, then stopping

Which drug reverses the effect of heparin?

1. AVitamin K
2. BNaloxone
3. CFlumazenil
4. DProtamine sulfate

In Addison's disease, fludrocortisone is given to replace which hormone?

1. AAldosterone
2. BThyroxine
3. CCortisol
4. DAdrenaline

Which blood test is commonly used to monitor a continuous infusion of unfractionated heparin?

1. ASerum potassium
2. BActivated partial thromboplastin time (aPTT)
3. CINR (international normalised ratio, prothrombin time)
4. DHaemoglobin A1c

Warfarin works by:

1. AActivating antithrombin
2. BBlocking platelet aggregation through irreversible inhibition of COX-1
3. CDirectly inhibiting thrombin
4. DBlocking the vitamin K-dependent synthesis of clotting factors

What is a loading dose used for?

1. ATo reach the target plasma concentration quickly
2. BTo test for allergic reactions
3. CTo slow down the absorption of the drug
4. DTo reduce side effects at the start of treatment

A patient on digoxin is started on amiodarone. What change should the nurse expect?

1. ADigoxin levels rise, so the digoxin dose is often reduced
2. BDigoxin levels fall sharply, so the digoxin dose is doubled
3. CNo interaction is expected
4. DAmiodarone levels fall to zero

Why is intravenous insulin given with glucose in severe hyperkalaemia?

1. AInsulin increases potassium excretion by the kidney
2. BInsulin protects the heart muscle directly from potassium
3. CGlucose binds potassium in the blood
4. DInsulin moves potassium from the blood into cells