1.Easy
Permethrin is used to treat:
- AScabies and head lice
- BFungal nail infections
- CPsoriasis
- DAcne
2.Easy
Which drug can be used in beta blocker overdose because it raises heart rate through a non-adrenergic pathway?
- AFlumazenil
- BNaloxone
- CInsulin
- DGlucagon
3.Easy
How does rasagiline help in Parkinson's disease?
- AIt blocks dopamine receptors in the brain
- BIt blocks acetylcholine receptors in the gut
- CIt is converted directly into dopamine inside brain neurones
- DIt inhibits MAO-B, so brain dopamine is broken down more slowly
4.Medium
A patient is starting doxazosin, an alpha-1 blocker. What should the nurse advise about the first dose?
- ATake it at bedtime, because it can cause dizziness and fainting
- BExpect a short rise in blood pressure after the dose
- CTake it only if the urine is darker than usual
- DTake it in the morning with a cup of strong coffee to stay alert
5.Medium
Which patient should usually not use the combined oral contraceptive pill?
- AA 30-year-old non-smoker with no medical problems
- BA 25-year-old woman with heavy periods
- CA 22-year-old non-smoker with acne
- DA 38-year-old woman who smokes 20 cigarettes a day
6.Medium
Apixaban and rivaroxaban are anticoagulants that directly inhibit:
- AFactor Xa
- BThrombin
- CVitamin K epoxide reductase
- DThe platelet P2Y12 receptor
7.Hard
A patient with severe chronic hyponatraemia receives hypertonic saline. Why is the rate of correction strictly limited?
- ARaising sodium too fast can cause osmotic demyelination in the brain
- BFast correction causes immediate kidney failure
- CHypertonic saline is toxic to the liver at high rates
- DRaising sodium too fast causes severe hypokalaemia and cardiac arrest
8.Hard
A drug is ordered at 5 micrograms/kg/min for an 80 kg patient. The infusion contains 1,600 micrograms per mL. What rate in mL/h is needed?
- A25 mL/h
- B150 mL/h
- C15 mL/h
- D4 mL/h
Answer key
- 1. A · Scabies and head lice
- 2. D · Glucagon
- 3. D · It inhibits MAO-B, so brain dopamine is broken down more slowly
- 4. A · Take it at bedtime, because it can cause dizziness and fainting
- 5. D · A 38-year-old woman who smokes 20 cigarettes a day
- 6. A · Factor Xa
- 7. A · Raising sodium too fast can cause osmotic demyelination in the brain
- 8. C · 15 mL/h
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