1.Easy
A fentanyl patch applied to the skin is an example of which route?
- ASubcutaneous
- BSublingual
- CTransdermal
- DIntradermal
2.Easy
Which long-term side effect of phenytoin makes good oral hygiene especially important?
- ABlue-grey discoloration of the teeth and gums
- BLoss of taste
- COvergrowth of the gums (gingival hyperplasia)
- DExcess saliva production
3.Easy
Vitamin D supplements support bone health mainly by:
- AStimulating osteoclasts to break down bone
- BIncreasing calcium absorption from the gut
- CIncreasing calcium loss in the urine
- DReplacing collagen in bone
4.Medium
Methylergometrine (methylergonovine) is prescribed for postpartum bleeding. Which finding would make the nurse withhold it and check with the prescriber?
- ATemperature of 37.2 °C (99 °F)
- BHeart rate of 88 per minute
- CBlood pressure of 160/105 mmHg
- DHaemoglobin slightly below normal
5.Medium
What does the clearance of a drug describe?
- AThe fraction of the dose that is absorbed
- BThe time needed for the drug to disappear completely from the plasma
- CThe amount of drug removed by one dialysis session
- DThe volume of plasma cleared of the drug per unit of time
6.Medium
Which technique is correct when giving subcutaneous enoxaparin from a prefilled syringe?
- AExpel the air bubble from the syringe first, then inject into the deltoid muscle
- BMassage the site well for one minute after the injection
- CInject into a vein on the back of the hand
- DInject into the abdomen away from the navel and do not rub the site afterwards
7.Hard
A patient on simvastatin is prescribed gemfibrozil. What is the main concern?
- ASevere hypoglycaemia
- BA sharp rise in LDL cholesterol and triglycerides
- CA much higher risk of myopathy and rhabdomyolysis
- DLoss of all lipid-lowering effect
8.Hard
The thalidomide disaster of the late 1950s and early 1960s is best known for which effect, and what did it lead to?
- ALiver failure in adults; the ban of all sedatives
- BDeafness in children; the end of animal testing
- CSevere limb defects in babies; stricter drug testing and regulation
- DHeart attacks in older adults; the start of generic medicines
Answer key
- 1. C · Transdermal
- 2. C · Overgrowth of the gums (gingival hyperplasia)
- 3. B · Increasing calcium absorption from the gut
- 4. C · Blood pressure of 160/105 mmHg
- 5. D · The volume of plasma cleared of the drug per unit of time
- 6. D · Inject into the abdomen away from the navel and do not rub the site afterwards
- 7. C · A much higher risk of myopathy and rhabdomyolysis
- 8. C · Severe limb defects in babies; stricter drug testing and regulation
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