1.Easy
Which of these drugs has a narrow therapeutic index?
- ALoratadine
- BLithium
- COmeprazole
- DAmoxicillin
2.Easy
How is pernicious anaemia usually treated?
- AWith blood transfusions every month
- BWith folic acid alone
- CWith oral iron tablets for three months, then stopping
- DWith vitamin B12 injections, usually for life
3.Easy
How does activated charcoal work in poisoning?
- AIt binds (adsorbs) the poison in the gut so less is absorbed
- BIt neutralises acids in the blood
- CIt makes the patient vomit the poison before it is absorbed
- DIt speeds up liver metabolism of the poison
4.Medium
After naloxone reverses an opioid overdose, why must the patient be watched closely?
- ANaloxone itself causes respiratory depression at high doses
- BNaloxone makes the opioid stay longer in the body
- CNaloxone may wear off before the opioid does, so breathing can slow again
- DNaloxone often causes severe low blood glucose a few hours after the dose
5.Medium
Which group of effects would the nurse expect after a dose of an anticholinergic drug such as atropine?
- ADiarrhoea, frequent urination and sweating
- BBronchial secretions, wheeze and tearing of the eyes
- CHeavy salivation, slow heart rate and small pupils
- DDry mouth, faster heart rate and dilated pupils
6.Medium
A prescriber gives a verbal medication order in an emergency. What should the nurse do?
- ARemember it and write it in the chart at the end of the shift
- BGive the drug without recording the order
- CWrite it down and read it back to the prescriber to confirm
- DAsk another nurse to remember the order
7.Hard
For a drug with first-order elimination, doubling the dose (without changing the interval) will:
- ADouble the steady-state level but not change the time to reach steady state
- BDouble the half-life
- CLeave the steady-state level unchanged but halve the time needed to reach it
- DHalve the time to reach steady state
8.Hard
Before starting rituximab, patients are tested for hepatitis B. Why?
- ARituximab can reactivate hepatitis B and cause liver failure
- BHepatitis B infection makes rituximab completely ineffective
- CRituximab is a vaccine against hepatitis B
- DRituximab is made from the hepatitis B virus
Answer key
- 1. B · Lithium
- 2. D · With vitamin B12 injections, usually for life
- 3. A · It binds (adsorbs) the poison in the gut so less is absorbed
- 4. C · Naloxone may wear off before the opioid does, so breathing can slow again
- 5. D · Dry mouth, faster heart rate and dilated pupils
- 6. C · Write it down and read it back to the prescriber to confirm
- 7. A · Double the steady-state level but not change the time to reach steady state
- 8. A · Rituximab can reactivate hepatitis B and cause liver failure
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