1.Easy
Where is a sublingual tablet placed?
- AIn the stomach, swallowed with water
- BUnder the tongue
- COn top of the tongue, then chewed
- DBetween the cheek and the gum
2.Easy
Which of these drugs has a narrow therapeutic index?
- ALithium
- BOmeprazole
- CLoratadine
- DAmoxicillin
3.Easy
Which description fits insulin glargine?
- AAn oral tablet that makes the pancreas release insulin
- BAn intermediate-acting cloudy insulin with a clear peak
- CA rapid-acting insulin given with each meal
- DA long-acting basal insulin with no marked peak
4.Medium
How long does it take, approximately, for a drug given at regular intervals to reach a steady state?
- AIt depends only on the dose size
- B10 half-lives
- C4 to 5 half-lives
- D1 half-life
5.Medium
A patient has severe kidney impairment. A drug is mainly excreted unchanged in the urine. What is the usual adjustment?
- AReduce the dose or lengthen the dosing interval
- BGive the drug orally instead of intravenously
- CIncrease the dose to make up for poor absorption
- DNo change is needed, because the liver takes over
6.Medium
A patient takes regular paracetamol (acetaminophen) at home. Which teaching point best prevents accidental overdose?
- ACheck cold and flu remedies, as many also contain paracetamol
- BTake paracetamol with alcohol to improve absorption
- CUse paracetamol only on an empty stomach
- DTake an extra dose if the first one does not work within 10 minutes
7.Hard
A patient starting sertraline is taught about the drug. Which statement shows a need for further teaching?
- A"I may have some nausea at first."
- B"It may take a few weeks to feel the full effect."
- C"I will tell someone if I have thoughts of harming myself."
- D"If I feel better after a week, I can stop taking it."
8.Hard
A patient is switched from oral to intravenous morphine. Why is the IV dose lower than the oral dose?
- AOral morphine has a large first-pass effect, so less reaches the blood
- BIV morphine is excreted much more slowly by the kidney than oral morphine
- CThe oral route causes tolerance faster than the IV route
- DIV morphine is a stronger chemical form of the drug
Answer key
- 1. B · Under the tongue
- 2. A · Lithium
- 3. D · A long-acting basal insulin with no marked peak
- 4. C · 4 to 5 half-lives
- 5. A · Reduce the dose or lengthen the dosing interval
- 6. A · Check cold and flu remedies, as many also contain paracetamol
- 7. D · "If I feel better after a week, I can stop taking it."
- 8. A · Oral morphine has a large first-pass effect, so less reaches the blood
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