Pharmacology worksheet with answers

Which plasma protein binds most acidic drugs, such as warfarin?

1. AAlbumin
2. BInsulin
3. CFibrinogen
4. DHaemoglobin

Sertraline, an antidepressant, increases the level of which neurotransmitter in the synapse?

1. ADopamine
2. BGABA
3. CSerotonin
4. DAcetylcholine

What is a prodrug?

1. AA drug that is given before surgery
2. BA drug that has passed all clinical trials
3. CA drug that is inactive until the body converts it into its active form
4. DA drug that prevents or reverses the effect of another drug in the body

Which rule applies to intravenous potassium chloride?

1. AIt is mixed into blood products to save time
2. BIt is given as a rapid IV push to correct low levels quickly
3. CIt must be diluted and given as an infusion, never as an IV push
4. DIt may be given intramuscularly if there is no IV access

A patient uses two different eye drops at the same time of day. What should the nurse advise?

1. AMix the drops in one bottle first
2. BPut both drops in at exactly the same moment
3. CWait at least 5 minutes between the two drops
4. DUse only one of them each day

A man takes finasteride. What should be explained about handling the tablets?

1. AThe tablets must be stored in the fridge
2. BPregnant women should not handle crushed or broken tablets
3. CAnyone can handle the tablets, as they contain no active drug
4. DThe tablets must be crushed before swallowing

Why is glibenclamide (glyburide) generally avoided in older adults?

1. AIt causes high blood glucose in older adults
2. BIt is not absorbed in people over 65
3. CIt causes severe weight loss and muscle wasting in older people
4. DIt is long-acting and can cause prolonged, severe hypoglycaemia

A drug has a volume of distribution of 40 L and complete bioavailability. Which loading dose gives a target plasma concentration of 2 mg/L?

1. A20 mg
2. B160 mg
3. C42 mg
4. D80 mg