1.Easy
Finasteride is used in benign prostatic hyperplasia because it:
- AInhibits 5-alpha reductase and slowly shrinks the prostate
- BRelaxes smooth muscle in the prostate within hours of the first dose
- CKills bacteria in the prostate
- DIncreases testosterone production
2.Easy
What does "bioavailability" describe?
- AHow quickly a drug is excreted
- BThe fraction of a dose that reaches the systemic circulation unchanged
- CThe fraction of a dose that is bound to plasma proteins in the circulation
- DHow strongly a drug binds to its receptor
3.Easy
Timolol eye drops are used mainly to treat:
- ADry eyes
- BGlaucoma
- CBacterial conjunctivitis
- DCataracts
4.Medium
What does the clearance of a drug describe?
- AThe volume of plasma cleared of the drug per unit of time
- BThe time needed for the drug to disappear completely from the plasma
- CThe fraction of the dose that is absorbed
- DThe amount of drug removed by one dialysis session
5.Medium
Which blood test is used to monitor warfarin therapy?
- ASerum albumin
- BPlatelet count
- CActivated partial thromboplastin time (aPTT)
- DINR (prothrombin time)
6.Medium
Besides lithium levels, which blood tests are monitored in long-term lithium treatment?
- AINR and fibrinogen
- BKidney function and thyroid function
- CLiver enzymes, serum amylase and lipase
- DTroponin and CK-MB
7.Hard
A patient starting sertraline is taught about the drug. Which statement shows a need for further teaching?
- A"I may have some nausea at first."
- B"It may take a few weeks to feel the full effect."
- C"If I feel better after a week, I can stop taking it."
- D"I will tell someone if I have thoughts of harming myself."
8.Hard
On admission, a patient's home medicine list includes warfarin for atrial fibrillation, but warfarin is not on the admission orders. What should the nurse do?
- AClarify the omission with the prescriber (medication reconciliation)
- BGive the patient's own warfarin brought from home without an order
- CTell the patient to stop warfarin permanently
- DAssume the omission is intended and do nothing
Answer key
- 1. A · Inhibits 5-alpha reductase and slowly shrinks the prostate
- 2. B · The fraction of a dose that reaches the systemic circulation unchanged
- 3. B · Glaucoma
- 4. A · The volume of plasma cleared of the drug per unit of time
- 5. D · INR (prothrombin time)
- 6. B · Kidney function and thyroid function
- 7. C · "If I feel better after a week, I can stop taking it."
- 8. A · Clarify the omission with the prescriber (medication reconciliation)
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