1.Easy
Why is low-dose aspirin given to some people with heart disease?
- ATo slow the heart rate
- BTo reduce platelet aggregation and prevent clots
- CTo lower blood cholesterol levels and stabilise plaques
- DTo relieve chest pain immediately
2.Easy
What does "bacteriostatic" mean?
- AThe drug kills viruses as well as bacteria
- BThe drug stops bacteria multiplying without killing them directly
- CThe drug prevents the patient's immune response
- DThe drug kills bacteria directly by breaking down their cell wall
3.Easy
Why are corticosteroids such as betamethasone given to a woman at risk of preterm birth?
- ATo prevent infection in the mother
- BTo stop contractions completely
- CTo lower the mother's blood glucose
- DTo speed up fetal lung maturity
4.Medium
Warfarin works by:
- ADirectly inhibiting thrombin
- BBlocking the vitamin K-dependent synthesis of clotting factors
- CActivating antithrombin
- DBlocking platelet aggregation through irreversible inhibition of COX-1
5.Medium
Intravenous vancomycin is commonly used to treat infections caused by:
- APseudomonas aeruginosa
- BEscherichia coli
- CCandida albicans
- DMRSA
6.Medium
Why should NSAIDs be used with caution in some people with asthma?
- AThey block the anti-inflammatory effect of inhaled corticosteroids
- BThey increase the clearance of salbutamol
- CThey cause mucus plugs by drying the airways
- DThey can trigger bronchospasm in aspirin-sensitive asthma
7.Hard
Which statement correctly contrasts donepezil and memantine in Alzheimer's disease?
- ADonepezil blocks NMDA receptors; memantine inhibits acetylcholinesterase
- BBoth drugs remove amyloid plaques from the brain
- CDonepezil inhibits cholinesterase; memantine blocks NMDA receptors
- DBoth drugs are dopamine agonists that differ only in their half-lives
8.Hard
Gentamicin is combined with high-dose intravenous furosemide. Which risk is especially increased?
- ALiver failure
- BDamage to hearing
- CHypoglycaemia
- DBleeding
Answer key
- 1. B · To reduce platelet aggregation and prevent clots
- 2. B · The drug stops bacteria multiplying without killing them directly
- 3. D · To speed up fetal lung maturity
- 4. B · Blocking the vitamin K-dependent synthesis of clotting factors
- 5. D · MRSA
- 6. D · They can trigger bronchospasm in aspirin-sensitive asthma
- 7. C · Donepezil inhibits cholinesterase; memantine blocks NMDA receptors
- 8. B · Damage to hearing
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