1.Easy
Which organ excretes most water-soluble drugs and their metabolites?
- ALiver
- BLung
- CSkin
- DKidney
2.Easy
Vitamin D supplements support bone health mainly by:
- AIncreasing calcium loss in the urine
- BStimulating osteoclasts to break down bone
- CIncreasing calcium absorption from the gut
- DReplacing collagen in bone
3.Easy
Benzodiazepines such as diazepam work by enhancing the effect of which neurotransmitter?
- AGABA
- BGlutamate
- CSerotonin
- DNoradrenaline
4.Medium
A nurse has a needlestick injury from a patient with HIV. When should post-exposure prophylaxis start?
- AOnly after the nurse's HIV test turns positive
- BAs soon as possible, and within 72 hours at the latest
- CAfter one week, when the risk of infection is clearer
- DOnly if the patient's viral load is above a set level
5.Medium
During adult cardiac arrest, how often is IV adrenaline (epinephrine) usually repeated?
- AEvery 15–20 minutes
- BOnce only, at the start
- CEvery 3–5 minutes
- DEvery 30 seconds
6.Medium
Patients on older MAO inhibitors are warned about foods rich in tyramine. What can happen?
- ASudden kidney failure
- BA hypertensive crisis
- CAn allergic rash
- DSevere hypoglycaemia
7.Hard
A patient on stable warfarin is prescribed a course of metronidazole. What is the likely effect, and what should the nurse expect?
- AMetronidazole replaces warfarin, so warfarin is stopped
- BThe INR falls, so the risk of clotting increases
- CThe INR stays the same, as these drugs do not interact
- DThe INR rises, so closer INR monitoring is needed
8.Hard
A patient receives high-dose IV aciclovir for herpes encephalitis. Which nursing action reduces the main risk to the kidneys?
- AKeep the patient well hydrated and give the infusion slowly
- BGive a loop diuretic before each dose
- CGive the infusion as a rapid push
- DRestrict oral and IV fluids to prevent brain swelling
Answer key
- 1. D · Kidney
- 2. C · Increasing calcium absorption from the gut
- 3. A · GABA
- 4. B · As soon as possible, and within 72 hours at the latest
- 5. C · Every 3–5 minutes
- 6. B · A hypertensive crisis
- 7. D · The INR rises, so closer INR monitoring is needed
- 8. A · Keep the patient well hydrated and give the infusion slowly
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