Pharmacology worksheet with answers

Free printable Pharmacology worksheet: 8 problems from easy to exam level, with an answer key. Print it or save it as a PDF.

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1.Easy

Which of these is a typical phase II (conjugation) reaction in drug metabolism?

  1. AOxidation
  2. BHydrolysis
  3. CReduction
  4. DGlucuronidation
2.Easy

Why is methadone used to treat opioid use disorder?

  1. AIt is a long-acting opioid that prevents withdrawal and craving
  2. BIt causes vomiting if other opioids are used
  3. CIt is a pure opioid antagonist that blocks all opioid effects
  4. DIt cures the liver damage caused by opioids
3.Easy

Disulfiram is used in alcohol use disorder because it:

  1. ACures liver damage caused by alcohol
  2. BRemoves alcohol from the blood faster
  3. CReplaces alcohol at its receptors in the brain
  4. DCauses an unpleasant reaction if alcohol is drunk
4.Medium

Which teaching about antiepileptic drugs is most important?

  1. AStop the drug when you have had no seizures for one whole week
  2. BTake a double dose if you feel a seizure coming
  3. CAlcohol has no effect on seizure control
  4. DDo not stop the drug suddenly, as this can trigger severe seizures
5.Medium

A patient with a fentanyl patch is given home-care advice. Which instruction is correct?

  1. AThrow used patches loose into the household bin with the packaging
  2. BCut the patch in half if the pain is mild
  3. CAvoid heating pads, hot baths and saunas over or near the patch
  4. DApply each new patch over the same skin area
6.Medium

A patient with difficulty swallowing is prescribed several tablets. Which one should not be crushed?

  1. AA plain paracetamol tablet
  2. BA modified-release (extended-release) tablet
  3. CA plain aspirin dispersible tablet
  4. DA tablet that the pharmacist says may be crushed
7.Hard

A woman with epilepsy who takes an antiepileptic drug plans to become pregnant. Which advice is standard?

  1. AAvoid folic acid because it lowers drug levels
  2. BNo change is needed, as antiepileptics carry no risk in pregnancy
  3. CTake folic acid before conception and seek specialist review of her medication
  4. DStop all antiepileptic drugs straight away as soon as she stops contraception
8.Hard

Why is vincristine labelled "for intravenous use only – fatal if given by other routes"?

  1. AAccidental intrathecal injection causes fatal ascending neurotoxicity
  2. BOral vincristine causes immediate anaphylaxis
  3. CSubcutaneous injection makes the drug inactive
  4. DIntramuscular injection causes severe and prolonged hypoglycaemia

Answer key

  1. 1. D · Glucuronidation
  2. 2. A · It is a long-acting opioid that prevents withdrawal and craving
  3. 3. D · Causes an unpleasant reaction if alcohol is drunk
  4. 4. D · Do not stop the drug suddenly, as this can trigger severe seizures
  5. 5. C · Avoid heating pads, hot baths and saunas over or near the patch
  6. 6. B · A modified-release (extended-release) tablet
  7. 7. C · Take folic acid before conception and seek specialist review of her medication
  8. 8. A · Accidental intrathecal injection causes fatal ascending neurotoxicity

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