1.Easy
Lithium is used mainly to treat which condition?
- ABipolar disorder
- BAttention deficit hyperactivity disorder
- CGeneralised anxiety disorder
- DSchizophrenia with no mood symptoms
2.Easy
Mesalazine (mesalamine) is used mainly to treat:
- AGallstones
- BPeptic ulcer
- CUlcerative colitis
- DIrritable bowel syndrome with constipation
3.Easy
Which herbal product is commonly taken for sleep and can add to the effect of sedatives?
- ACranberry
- BPeppermint
- CValerian
- DGinger
4.Medium
A patient takes theophylline for COPD. Which advice is most important?
- ADrink plenty of grapefruit juice each morning to improve absorption
- BAvoid potassium-rich foods such as bananas
- CLimit coffee, tea and cola, because caffeine adds to the side effects
- DTake extra doses when short of breath
5.Medium
Which advice helps reduce the most common side effect of varenicline?
- ATake double doses in the first week
- BTake it after food with a full glass of water
- CTake it with alcohol to reduce nausea
- DTake it on an empty stomach at bedtime with a little milk
6.Medium
Which blood test is used to monitor warfarin therapy?
- ASerum albumin
- BINR (prothrombin time)
- CActivated partial thromboplastin time (aPTT)
- DPlatelet count
7.Hard
A patient receiving frequent salbutamol (albuterol) nebulisers develops a fine tremor and a heart rate of 120 per minute. What is the best explanation?
- AThe patient is allergic to salbutamol and needs adrenaline
- BSalbutamol blocks muscarinic receptors in the heart
- CSalbutamol causes high potassium, which speeds the heart and causes muscle twitching
- DAt high doses it also stimulates beta receptors in skeletal muscle and the heart
8.Hard
A malnourished patient with low serum albumin shows nystagmus and unsteady gait. Her total phenytoin level is within range. What is the most likely explanation?
- AThe total level is high, but the laboratory is wrong
- BLow albumin speeds up phenytoin metabolism
- CLow albumin makes phenytoin bind more tightly, so the drug is less active
- DMore phenytoin is unbound when albumin is low, so free levels rise
Answer key
- 1. A · Bipolar disorder
- 2. C · Ulcerative colitis
- 3. C · Valerian
- 4. C · Limit coffee, tea and cola, because caffeine adds to the side effects
- 5. B · Take it after food with a full glass of water
- 6. B · INR (prothrombin time)
- 7. D · At high doses it also stimulates beta receptors in skeletal muscle and the heart
- 8. D · More phenytoin is unbound when albumin is low, so free levels rise
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