感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 34 道练习题,完整解答附在最后。
Why should a patient wash and dry their hands before a fingerprick glucose test?
During a handover the nurse notices a colleague is sharing patient details loudly in a busy corridor. What should the nurse do?
A colleague has drawn up a medication and asks the nurse to give it to her patient. What should the nurse do?
A patient with pulmonary tuberculosis has been on treatment. Which findings usually allow airborne isolation to end?
哪种定时给药的药物时间要求最严格?
After handover on a medical unit, which patient should the nurse see first?
Which is the correct technique for using a metered-dose inhaler without a spacer?
A patient has a single hot, swollen, very painful knee and a fever. Why is urgent joint aspiration important?
A patient takes low-dose methotrexate weekly for rheumatoid arthritis. Which laboratory tests are monitored regularly?
A patient has eaten very little for 2 weeks and has received broad-spectrum antibiotics. The INR is now 2.3 without warfarin, and the platelets are normal. What is the most likely cause?
Which blood test is commonly used to monitor a continuous infusion of unfractionated heparin?
A patient on weekly methotrexate is prescribed trimethoprim for a urinary infection. What is the main risk?
Why are patients with mitral stenosis at high risk of atrial fibrillation?
在严重哮喘发作期间,一名患者的 PaCO₂ 从偏低升至正常,同时看起来精疲力竭。这意味着什么?
Why is once-daily prednisolone usually taken in the morning with food?
一名服用丙戊酸盐的癫痫女性说她正计划怀孕。哪种回应最恰当?
Which finding suggests a deep tissue pressure injury?
一名使用阿片类药物 PCA 的患者经面罩吸氧。SpO₂ 97%,呼吸频率 11 次/分,但现在很难唤醒。护士应得出什么结论?
Which statement about the lactational amenorrhoea method (LAM) is correct?
A woman at 8 weeks takes valproate for epilepsy. She asks whether she should stop it. Which response is best?
Which sign shows that a baby is ready to start solid foods?
Several family members, including the children, have had headaches, nausea and drowsiness all winter. They feel better when away from home. What should the nurse suspect?
An 80-year-old man often talks about his life and his achievements. According to Erikson, which task is he working on?
A man whose wife died a month ago is rude and angry with the nurses about small things. What is the best understanding of his behaviour?
练习题(虚构数值,不作为临床指导)。 一位患者的体温为 38.2 °C。用 °F = °C × 9/5 + 32 把它换算为华氏度T。取到一位小数。
练习题(虚构数值,不作为临床指导)。 一张处方写着口服混悬液½ tsp,每 12 小时一次,共 14 天。混悬液每瓶 50 mL。按1 tsp = 5 mL,必须提供多少整瓶N才能完成疗程?
某患者体重 22 kg。医嘱剂量为每天 2 mg/kg,分 4 次等量给药。每次给多少毫克 D?
你需要用 25%(w/v)储备液配制 500 mL 2.5%(w/v)溶液。 你需要多少容量的储备液 V₁?
医嘱要求在 10 小时内输入 1000 mL。8 小时后你发现袋中还剩 240 mL,而输液仍须按时完成。 必须把泵重新设定为多少 mL/h 的速率 R?
一袋中含有 1 g 药物,溶于 250 mL。医嘱为每分钟 4 mg。泵速 R 应设为多少 mL/h?
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 8 小时班次中的出入量。静脉输液在整个班次中按所示速率输注。求液体平衡 B = 入量 − 出量,以 mL 计(答案为负表示净丢失)。 冰屑按其体积的一半计。
练习题(虚构数值,不作为临床指导)。 一袋 500 mL 的液体于 12:45 开始用输液泵以 125 mL/h 输注。到 13:45 时袋中还剩多少 mL V?
练习题(虚构数值,不作为临床指导)。 用 Morse 跌倒评分评估一位练习患者:过去 3 个月内的跌倒史: 是; 次要诊断: 否; 行走辅助: 拐杖、手杖或助行器; 静脉输液或封管: 否; 步态: 受损; 精神状态: 了解自身局限。求 Morse 总分MFS。
练习题(虚构数值,不作为临床指导)。 一名成人体重 81 kg,身高 162 cm。计算 BMI 并点击 WHO 体重分类。
答案: C · Sugar on the skin can give a falsely high reading
Traces of food or drink on the finger can raise the reading. Washing with water and drying fully gives an accurate result; alcohol wipes can also affect some meters.
答案: A · Suggest moving the handover to a private place
Information shared for care must still be protected from people who do not need it. Moving to a private area or speaking quietly at the bedside protects patient confidentiality.
答案: C · Decline, and give only medications that the nurse prepared or checked personally
Nurses give only medicines they prepared themselves or verified fully, because they are accountable for what they give. A drug prepared by someone else may be wrong in ways the nurse cannot see.
答案: B · Three negative sputum smears, clinical improvement and continued therapy
Airborne precautions usually continue until the patient is on effective therapy, is improving clinically and has three negative sputum smears for acid-fast bacilli, according to policy.
答案: B · 随已送到的早餐托盘一起给予的速效胰岛素
速效胰岛素随餐给药;给得晚或不进食可导致血糖过高或过低。其他每日用药稍晚一点给予也无妨。
答案: D · New atrial fibrillation, heart rate 150/min, blood pressure 86/50 mmHg, dizzy
Rapid atrial fibrillation with hypotension and dizziness means the heart is not pumping enough blood; the patient is unstable. The other patients are within target or have predictable needs.
答案: D · Breathe out, then breathe in slowly and deeply while pressing the canister, then hold
The patient breathes out, seals the lips around the mouthpiece, starts breathing in slowly, presses the canister and continues a deep breath, then holds it for about 10 seconds. Spacers make coordination easier.
答案: B · To rule out septic arthritis, which can rapidly destroy the joint
Septic arthritis can destroy cartilage within days. Aspiration allows microscopy and culture, and helps distinguish infection from crystal arthritis such as gout.
答案: A · Complete blood count, liver tests and kidney function
Methotrexate can cause bone marrow suppression, liver toxicity and, as it is cleared by the kidneys, toxicity when kidney function falls. The CBC, liver tests and creatinine are checked regularly, and folic acid is usually given to reduce adverse effects.核对依据: Methotrexate · StatPearls (NCBI Bookshelf) (2024)
答案: A · Vitamin K deficiency
Vitamin K comes from the diet and from gut bacteria. Poor intake plus antibiotics can cause vitamin K deficiency, which lowers factors II, VII, IX and X and prolongs the PT/INR. Vitamin K replacement corrects it.核对依据: Vitamin K Deficiency in Neonates and Adults (StatPearls) · StatPearls (NCBI Bookshelf) (2026); Prothrombin time (PT) · MedlinePlus (NIH) (2025)
答案: C · Activated partial thromboplastin time (aPTT)
Unfractionated heparin is often monitored with the aPTT, and the infusion rate is adjusted according to a protocol. Low-molecular-weight heparins usually do not need routine aPTT checks.
答案: C · Bone marrow suppression, because both drugs inhibit folate metabolism
Trimethoprim and methotrexate both inhibit dihydrofolate reductase, and trimethoprim also reduces methotrexate excretion. The combination can cause severe pancytopenia, so another antibiotic is chosen.
答案: D · The left atrium enlarges as it pushes blood through the narrow valve
A narrowed mitral valve raises pressure in the left atrium, which dilates. A stretched atrium is prone to atrial fibrillation, and blood stasis there carries a high risk of clots and stroke. Anticoagulation is therefore essential in mitral stenosis with AF.
答案: C · 患者正在疲劳,随后可能发生呼吸衰竭
发作早期,过度通气会使 PaCO₂ 降低。呼吸困难且正在疲劳的患者 PaCO₂ 正常或升高,意味着通气功能衰竭,是危及生命的特征。需要紧急的高级医师和重症监护评估。
答案: C · To match the natural cortisol rhythm and protect the stomach
Morning dosing mimics the normal early-morning cortisol peak, causes less adrenal suppression and less sleep disturbance. Taking it with food reduces gastric irritation.
答案: D · 建议不要突然停药,并尽快进行专科评估
丙戊酸盐具有高度致畸性(神经管缺陷和神经发育问题),在可能怀孕者中的使用受到严格限制。然而,突然停用抗癫痫药物有发生癫痫持续状态的风险。需要紧急的专科评估以规划更安全的替代方案,并补充叶酸。
答案: A · Intact skin that is purple or maroon over a bony area
A deep tissue injury appears as persistent purple, maroon or dark discolouration, or a blood-filled blister, from pressure and shear on underlying tissue. It may quickly turn into a deep wound.
答案: A · 很可能是阿片类药物中毒;氧气可能掩盖了通气不足
补充氧气可使 SpO₂ 保持正常,而 CO₂ 却因通气不足而升高。镇静加深是阿片类药物中毒的早期征象。护士应停止 PCA,刺激患者,呼叫援助并遵循纳洛酮方案,密切监测呼吸频率、深度和镇静程度。
答案: B · It needs full breastfeeding, no periods and a baby under 6 months
LAM is effective only if the mother is fully or nearly fully breastfeeding day and night, her periods have not returned and the baby is under 6 months. Ovulation can occur before the first period.
答案: B · Do not stop it suddenly; arrange urgent specialist review
Valproate is strongly teratogenic, but stopping antiepileptics suddenly can cause seizures that harm mother and fetus. She needs urgent specialist review to change treatment safely, ideally before conception.
答案: C · Sits with support, holds the head steady and shows interest in food
Readiness for solids, usually around 6 months, includes good head control, sitting with support, interest in food and loss of the tongue-thrust reflex. Night waking and teething are not signs of readiness.
答案: B · Carbon monoxide poisoning
Carbon monoxide from faulty heaters or boilers causes headache, nausea, dizziness and drowsiness that improve away from the source. Pulse oximetry can look falsely normal. Treatment is removal from the source and high-flow oxygen; the appliance must be checked.
答案: A · Integrity versus despair
In later life, the task is to look back and find meaning in one's life. Reminiscence supports a sense of integrity; failure leads to regret and despair.
答案: A · His anger may be part of grief, displaced onto staff, so she should not take it personally
Anger is a common part of grief and may be directed at staff who are safer targets. The nurse responds calmly, sets limits if needed and invites him to talk about his loss.
答案: T = 100.8 °F
温度:°C = (°F − 32) × 5/9,°F = °C × 9/5 + 32。从 °F 换算时先减 32 再乘,从 °C 换算时先乘再加 32。快速核对:37 °C 为 98.6 °F,每 1 °C 相当于 1.8 °F。
答案: N = 2
量纲分析:先写出已知量,再乘以写成分数形式的换算系数(例如 60 min/1 h 或 1 mg/1000 mcg),使每个不需要的单位在分子和分母各出现一次并相互约去。只剩下所求单位时再计算。使用题目给出的等量关系,只对最终答案取整。
答案: D = 11 mg
剂量计算:给药量等于医嘱剂量除以现有药物的规格,再乘以该规格对应的量:给药量 = (医嘱剂量/储备规格) × 储备体积。始终统一单位(先把 g 换成 mg,mg 换成 mcg),并检查答案是否合理。
答案: V₁ = 50 mL
Solution strengths: a percentage strength is grams per 100 mL, so 1% = 1 g/100 mL = 10 mg/mL. A ratio strength 1:1000 means 1 g in 1000 mL = 1 mg/mL; 1:10 000 is 0.1 mg/mL. For a dilution the amount of drug stays the same: C₁·V₁ = C₂·V₂.
答案: R = 120 mL/h
Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.
许多医院允许在不重开医嘱的情况下进行不超过 25% 的此类调整;请查阅本院规定。
答案: R = 60 mL/h
Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).
答案: B = 115 mL
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
为正:摄入的液体多于排出的液体。
答案: V = 375 mL
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: MFS = 60
Morse 跌倒评分:六个条目。跌倒史:否 0 分,是 25 分。次要诊断:否 0 分,是 15 分。行走辅助:无、卧床休息或护士协助 0 分;拐杖、手杖或助行器 15 分;扶着家具 30 分。静脉输液或封管:否 0 分,是 20 分。步态:正常、卧床休息或轮椅 0 分;虚弱 10 分;受损 20 分。精神状态:了解自身局限 0 分;高估或忘记自身局限 15 分。总分为 0 至 125。各医院的风险分界值不同;常用的一套是 0–24 低风险,25–44 中度风险,45 及以上为高风险。
答案: 肥胖 I 级
体质指数:BMI = 体重(kg)/身高(m)²,身高要先换算为米。使用磅和英寸时,BMI = 703 × 体重(lb)/身高(in)²。WHO 成人分类:低于 18.5 为体重过轻,18.5–24.9 为健康体重,25.0–29.9 为超重,30.0–34.9 为肥胖 I 级,35.0–39.9 为肥胖 II 级,40 及以上为肥胖 III 级。
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